Detalhe da pesquisa
1.
Hydrophobic moment drives penetration of bacterial membranes by transmembrane peptides.
J Biol Chem
; 299(11): 105266, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37734555
2.
The Human Mutation K237_V238del in a Putative Lipid Binding Motif within the V-ATPase a2 Isoform Suggests a Molecular Mechanism Underlying Cutis Laxa.
Int J Mol Sci
; 25(4)2024 Feb 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38396846
3.
Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association.
Int J Mol Sci
; 24(5)2023 Mar 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36902293
4.
Transmembrane peptide effects on bacterial membrane integrity and organization.
Biophys J
; 121(17): 3253-3262, 2022 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35923102
5.
Enhanced proteolytic resistance of cationic antimicrobial peptides through lysine side chain analogs and cyclization.
Biochem Biophys Res Commun
; 612: 105-109, 2022 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35512459
6.
Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides.
Biochemistry
; 60(34): 2586-2592, 2021 08 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34423969
7.
CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor.
J Biol Chem
; 295(7): 1985-1991, 2020 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31882543
8.
Structure of the EmrE multidrug transporter and its use for inhibitor peptide design.
Proc Natl Acad Sci U S A
; 115(34): E7932-E7941, 2018 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30082384
9.
Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB.
Proc Natl Acad Sci U S A
; 115(7): 1505-1510, 2018 02 13.
Artigo
Inglês
| MEDLINE | ID: mdl-29378946
10.
Peptide-Based Approach to Inhibition of the Multidrug Resistance Efflux Pump AcrB.
Biochemistry
; 59(41): 3973-3981, 2020 10 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33026802
11.
Peptide-Based Efflux Pump Inhibitors of the Small Multidrug Resistance Protein from Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 63(9)2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31209007
12.
Structural effects of extracellular loop mutations in CFTR helical hairpins.
Biochim Biophys Acta Biomembr
; 1860(5): 1092-1098, 2018 May.
Artigo
Inglês
| MEDLINE | ID: mdl-29307731
13.
Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides.
Bioorg Med Chem
; 26(6): 1189-1196, 2018 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29275987
14.
Therapeutic design of peptide modulators of protein-protein interactions in membranes.
Biochim Biophys Acta Biomembr
; 1859(4): 577-585, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-27580024
15.
Modulating Transmembrane α-Helix Interactions through pH-Sensitive Boundary Residues.
Biochemistry
; 55(31): 4306-15, 2016 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27434090
16.
Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.
Biochemistry
; 55(40): 5772-5779, 2016 Oct 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27620701
17.
Efflux by small multidrug resistance proteins is inhibited by membrane-interactive helix-stapled peptides.
J Biol Chem
; 290(3): 1752-9, 2015 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25425644
18.
Structural impact of proline mutations in the loop region of an ancestral membrane protein.
Biopolymers
; 106(1): 37-42, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26566586
19.
Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts.
Proc Natl Acad Sci U S A
; 110(39): 15668-73, 2013 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-24019476
20.
Protection or Destruction: The LL-37/HNP1 Cooperativity Switch.
Biophys J
; 119(12): 2370-2371, 2020 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33271082