Detalhe da pesquisa
1.
A gossypol derivative effectively protects against Zika and dengue virus infection without toxicity.
BMC Biol
; 20(1): 143, 2022 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35706035
2.
Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Int J Mol Sci
; 23(24)2022 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36555641
3.
Design, synthesis, and antiviral activity of a series of CD4-mimetic small-molecule HIV-1 entry inhibitors.
Bioorg Med Chem
; 32: 116000, 2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33461144
4.
α-Helix-Mimetic Foldamers for Targeting HIV-1 TAR RNA.
Chemistry
; 25(30): 7265-7269, 2019 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-30825250
5.
Targeting HIV-TB coinfection by developing novel piperidin-4-substituted imines: Design, synthesis, in vitro and in silico studies.
Arch Pharm (Weinheim)
; 352(6): e1800358, 2019 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-31066103
6.
Antiviral Activity of Dual-acting Hydrocarbon-stapled Peptides against HIV-1 Predominantly Circulating in China.
Biomed Environ Sci
; 30(6): 398-406, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-28705263
7.
Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity.
Bioorg Med Chem
; 24(22): 5988-6003, 2016 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27707628
8.
Synthesis, antiviral activity and resistance of a novel small molecule HIV-1 entry inhibitor.
Bioorg Med Chem
; 23(24): 7618-28, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26602829
9.
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc Natl Acad Sci U S A
; 109(15): 5663-8, 2012 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22451932
10.
Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.
Antimicrob Agents Chemother
; 58(9): 5478-91, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25001301
11.
Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development.
J Virol
; 87(17): 9939-42, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23824801
12.
Design of antiviral stapled peptides containing a biphenyl cross-linker.
Bioorg Med Chem Lett
; 24(7): 1748-51, 2014 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24613163
13.
Dual-acting stapled peptides target both HIV-1 entry and assembly.
Retrovirology
; 10: 136, 2013 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24237936
14.
Expansion of the Kell blood group system: two new high-prevalence antigens and two novel K0 (Kellnull ) phenotypes.
Transfusion
; 53(11 Suppl 2): 2887-91, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23968329
15.
Molecular basis of two novel and related high-prevalence antigens in the Kell blood group system, KUCI and KANT, and their serologic and spatial association with K11 and KETI.
Transfusion
; 53(11 Suppl 2): 2872-81, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23560718
16.
Discovery of Highly Potent Small Molecule Pan-Coronavirus Fusion Inhibitors.
Viruses
; 15(4)2023 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37112982
17.
Comparative Pharmacokinetics of a Dual Inhibitor of HIV-1, NBD-14189, in Rats and Dogs with a Proof-of-Concept Evaluation of Antiviral Potency in SCID-hu Mouse Model.
Viruses
; 14(10)2022 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36298823
18.
Design, Synthesis, and Antiviral Activity of the Thiazole Positional Isomers of a Potent HIV-1 Entry Inhibitor NBD-14270.
ChemMedChem
; 17(22): e202200344, 2022 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36097139
19.
Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain.
Retrovirology
; 8: 28, 2011 May 03.
Artigo
Inglês
| MEDLINE | ID: mdl-21539734
20.
Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41.
Bioorg Med Chem Lett
; 21(22): 6895-8, 2011 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21978673