Detalhe da pesquisa
1.
Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection.
PLoS Pathog
; 18(1): e1010227, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35041705
2.
Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.
Proc Natl Acad Sci U S A
; 118(1)2021 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33443167
3.
Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal.
PLoS Genet
; 15(3): e1007948, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30870413
4.
Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease.
J Neurosci
; 37(14): 3776-3788, 2017 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28275164
5.
Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice.
Blood
; 128(5): 721-31, 2016 08 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27252233
6.
Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion.
Blood
; 125(3): 427-37, 2015 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25336631
7.
Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.
Blood
; 126(15): 1844-55, 2015 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-26286849
8.
Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense.
Blood
; 126(17): 2047-58, 2015 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-26228483
9.
Early detection of thrombin activity in neuroinflammatory disease.
Ann Neurol
; 75(2): 303-8, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24740641
10.
Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia.
Blood
; 121(10): 1783-94, 2013 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23299312
11.
Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMß2 leukocyte integrin receptor.
Hum Mol Genet
; 21(9): 1989-2004, 2012 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22381526
12.
Platelet TGF-ß1 contributions to plasma TGF-ß1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload.
Blood
; 119(4): 1064-74, 2012 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22134166
13.
The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease.
J Exp Med
; 204(3): 571-82, 2007 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-17339406
14.
The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A.
Blood
; 117(23): 6326-37, 2011 Jun 09.
Artigo
Inglês
| MEDLINE | ID: mdl-21436072
15.
Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain.
Blood
; 118(10): 2889-95, 2011 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-21788337
16.
Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence.
J Biol Chem
; 286(11): 9865-74, 2011 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-21247890
17.
Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo.
Blood
; 116(24): 5191-9, 2010 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-20876456
18.
Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage.
J Neurosci
; 30(17): 5843-54, 2010 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-20427645
19.
Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis.
Kidney Int
; 80(10): 1035-44, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21734641
20.
Reduced thrombin generation increases host susceptibility to group A streptococcal infection.
Blood
; 113(6): 1358-64, 2009 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-19056689