Detalhe da pesquisa
1.
The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion.
J Biol Chem
; 294(42): 15257-15270, 2019 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31431503
2.
5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts.
BMC Cancer
; 20(1): 1090, 2020 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33176741
3.
An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis.
Haematologica
; 102(1): 79-84, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27686378
4.
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia.
Nat Cancer
; 2024 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38637657
5.
Bone marrow stromal cells reduce low-dose cytarabine-induced differentiation of acute myeloid leukemia.
Front Pharmacol
; 14: 1258151, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37954840
6.
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Nat Commun
; 14(1): 2132, 2023 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37059720
7.
C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia.
Cancer Discov
; 13(7): 1720-1747, 2023 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37012202
8.
Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis.
Sci Rep
; 12(1): 11344, 2022 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35790845
9.
All-trans retinoic acid induces differentiation in primary acute myeloid leukemia blasts carrying an inversion of chromosome 16.
Int J Hematol
; 115(1): 43-53, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-34546543
10.
The Role of Metabolism in the Development of Personalized Therapies in Acute Myeloid Leukemia.
Front Oncol
; 11: 665291, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34094959
11.
AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review.
Cells
; 10(5)2021 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34064363
12.
The Role of AMPK/mTOR Modulators in the Therapy of Acute Myeloid Leukemia.
Curr Med Chem
; 26(12): 2208-2229, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-29345570
13.
Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts.
Hemasphere
; 8(1): e28, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38434525
14.
5-Aminoimidazole-4-carboxamide ribonucleoside-induced autophagy flux during differentiation of monocytic leukemia cells.
Cell Death Discov
; 3: 17066, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28975042
15.
Inositol pyrophosphates modulate cell cycle independently of alteration in telomere length.
Adv Biol Regul
; 60: 22-28, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26446451
16.
The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation.
Int J Hematol
; 102(1): 12-24, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25758096
17.
5-Aminoimidazole-4-carboxamide ribonucleoside induces differentiation of acute myeloid leukemia cells.
Leuk Lymphoma
; 55(10): 2375-83, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24359245
18.
Combined inhibition of PI3K and mTOR exerts synergistic antiproliferative effect, but diminishes differentiative properties of rapamycin in acute myeloid leukemia cells.
Pathol Oncol Res
; 17(3): 645-56, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21336564