Detalhe da pesquisa
1.
TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.
Mol Cell
; 81(7): 1411-1424.e7, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33567268
2.
Development of STING degrader with double covalent ligands.
Bioorg Med Chem Lett
; 102: 129677, 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38408510
3.
Photo-regulated PROTACs: A novel tool for temporal control of targeted protein degradation.
Bioorg Med Chem Lett
; 107: 129778, 2024 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38702019
4.
Expansion of targeted degradation by Gilteritinib-Warheaded PROTACs to ALK fusion proteins.
Bioorg Chem
; 145: 107204, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38377822
5.
Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction.
Chem Pharm Bull (Tokyo)
; 72(5): 471-474, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38749738
6.
Rational Design of Amphipathic Antimicrobial Peptides with Alternating L-/D-Amino Acids That Form Helical Structures.
Chem Pharm Bull (Tokyo)
; 72(2): 149-154, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38296556
7.
In Silico Prediction of N-Nitrosamine Formation Pathways of Pharmaceutical Products.
Chem Pharm Bull (Tokyo)
; 72(2): 166-172, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38296559
8.
Structural Optimization of Decoy Oligonucleotide-Based PROTAC That Degrades the Estrogen Receptor.
Bioconjug Chem
; 34(10): 1780-1788, 2023 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37736001
9.
Synthesis and properties of PNA containing a dicationic nucleobase based on N4-benzoylated cytosine.
Bioorg Med Chem Lett
; 88: 129287, 2023 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37094725
10.
In silico optimization of peptides that inhibit Wnt/ß-catenin signaling.
Bioorg Med Chem
; 84: 117264, 2023 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37003158
11.
CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles.
Bioorg Med Chem
; 84: 117259, 2023 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37018877
12.
Development of decoy oligonucleotide-warheaded chimeric molecules targeting STAT3.
Bioorg Med Chem
; 95: 117507, 2023 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37922656
13.
Development of versatile solid-phase methods for syntheses of PROTACs with diverse E3 ligands.
Bioorg Med Chem
; 86: 117293, 2023 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37126968
14.
Advanced Solid-State NMR Analysis of Two Crystal Forms of Ranitidine Hydrochloride: Detection of 1H-14N Intra-/Intermolecular Correlations.
Chem Pharm Bull (Tokyo)
; 71(1): 58-63, 2023 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36288936
15.
Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers.
Int J Mol Sci
; 24(14)2023 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37511527
16.
Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity.
Bioconjug Chem
; 33(7): 1311-1318, 2022 07 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35737901
17.
Copper-Catalyzed Asymmetric Oxidative Desymmetrization of 2-Substituted 1,2,3-Triols.
J Org Chem
; 87(9): 6479-6491, 2022 May 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35468286
18.
Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates.
Pharm Res
; 39(1): 89-103, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-34961908
19.
Development of delivery carriers for plasmid DNA by conjugation of a helical template to oligoarginine.
Bioorg Med Chem
; 72: 116997, 2022 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36088811
20.
Development of a penetratin-conjugated stapled peptide that inhibits Wnt/ß-catenin signaling.
Bioorg Med Chem
; 73: 117021, 2022 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36198218