Ischemic preconditioning increases spinal excitability and voluntary activation during maximal plantar flexion contractions in men.

The enigmatic benefits of acute limb ischemic preconditioning (IP) in enhancing muscle force and exercise performance have intrigued researchers. This study sought to unravel the underlying mechanisms, focusing on increased neural drive and the role of spinal excitability while excluding peripheral factors. Soleus Hoffmann (H)-reflex /M-wave recruitment curves and unpotentiated supramaximal responses were recorded before and after IP or a low-pressure control intervention. Subsequently, the twitch interpolation technique was applied during maximal voluntary contractions to assess conventional parameters of neural output. Following IP, there was an increase in both maximum normalized force and voluntary activation (VA) for the plantar flexor group, with negligible peripheral alterations. Greater benefits were observed in participants with lower VA levels. Despite greater H-reflex gains, soleus volitional (V)-wave and sEMG amplitudes remained unchanged. In conclusion, IP improves muscle force via enhanced neural drive to the muscles. This effect appears associated, at least in part, to reduced presynaptic inhibition and/or increased motoneuron excitability. Furthermore, the magnitude of the benefit is inversely proportional to the skeletal muscle's functional reserve, making it particularly noticeable in under-recruited muscles. These findings have implications for the strategic application of the IP procedure across diverse populations.

Effects of high-intensity interval training and resistance training on physiological parameters and performance of well-trained runners: A randomized controlled trial.

This study aimed to verify the effects of 4 weeks of high-intensity interval training (HIIT), heavy (HRT) and explosive (ERT) resistance training on aerobic, anaerobic and neuromuscular parameters and performance of well-trained runners. Twenty-six male athletes were divided into HIIT (n = 10), HRT (n = 7) and ERT (n = 9) groups. Maximal oxygen uptake (VO2max) and the corresponding velocity (vVO2max), anaerobic threshold (AT), running economy (RE), oxygen uptake kinetics, lower-body strength (1RM) and power (CMJ), and the 1500m and 5000m time-trial (TT) were determined. Improvements were observed in vVO2max (mean difference (Δ): 2.6%; effect size (ES): 0.63) with HIIT, while AT was incresead in ERT (Δ: 4.3%; ES: 0.73) and HRT (Δ: 6.9%; ES: 0.72) groups. The CMJ performance was increased in ERT (Δ: 13.8%; ES: 1.03), HRT (Δ: 6.9%; ES: 0.55) and HIIT (Δ: 5.4%; ES: 0.34), whereas 1RM increase in HRT (Δ: 38.1%; ES: 1.21) and ERT (Δ: 49.2%; ES: 0.96) groups. HIIT improved the 1500m (Δ: -2.3%; ES: -0.62) and both HRT (Δ: -1.6%; ES: -0.32) and ERT (Δ: -1.7%; ES: -0.31) the 5000m TT. Despite performance adaptations were dependent on the training characteristics, both RT and HIIT model constitute an alternative for training periodization.

Agreement Between Maximal Lactate Steady State and Critical Power in Different Sports: A Systematic Review and Bayesian's Meta-Regression.

ABSTRACT: Borszcz, FK, de Aguiar, RA, Costa, VP, Denadai, BS, and de Lucas, RD. Agreement between maximal lactate steady state and critical power in different sports: A systematic review and Bayesian's meta-regression. J Strength Cond Res 38(6): e320-e339, 2024-This study aimed to systematically review the literature and perform a meta-regression to determine the level of agreement between maximal lactate steady state (MLSS) and critical power (CP). Considered eligible to include were peer-reviewed and "gray literature" studies in English, Spanish, and Portuguese languages in cyclical exercises. The last search was made on March 24, 2022, on PubMed, ScienceDirect, SciELO, and Google Scholar. The study's quality was evaluated using 4 criteria adapted from the COSMIN tool. The level of agreement was examined by 2 separate meta-regressions modeled under Bayesian's methods, the first for the mean differences and the second for the SD of differences. The searches yielded 455 studies, of which 36 studies were included. Quality scale revealed detailed methods and small samples used and that some studies lacked inclusion/exclusion criteria reporting. For MLSS and CP comparison, likely (i.e., coefficients with high probabilities) covariates that change the mean difference were the MLSS time frame and delta criteria of blood lactate concentration, MLSS number and duration of pauses, CP longest predictive trial duration, CP type of predictive trials, CP model fitting parameters, and exercise modality. Covariates for SD of the differences were the subject's maximal oxygen uptake, CP's longest predictive trial duration, and exercise modality. Traditional MLSS protocol and CP from 2- to 15-minute trials do not reflect equivalent exercise intensity levels; the proximity between MLSS and CP measures can differ depending on test design, and both MLSS and CP have inherent limitations. Therefore, comparisons between them should always consider these aspects.

Energy metabolism and muscle activation heterogeneity explain V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ slow component and muscle fatigue of cycling at different intensities.

NEW FINDINGS: What is the central question of this study? What are the physiological mechanisms underlying muscle fatigue and the increase in the O2 cost per unit of work during high-intensity exercise? What is the main finding and its importance? Muscle fatigue happens before, and does not explain, the V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ slow component ( V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ ), but they share the same origin. Muscle activation heterogeneity is associated with muscle fatigue and V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ . Knowing this may improve training prescriptions for healthy people leading to improved public health outcomes. ABSTRACT: This study aimed to explain the V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ slow component ( V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ ) and muscle fatigue during cycling at different intensities. The muscle fatigue of 16 participants was determined through maximal isokinetic effort lasting 3 s during constant work rate bouts of moderate (MOD), heavy (HVY) and very heavy intensity (VHI) exercise. Breath-by-breath V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ , near-infrared spectroscopy signals and EMG activity were analysed (thigh muscles). V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ was higher during VHI exercise (∼70% vs. ∼28% of V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ reserve in HVY). The deoxygenated haemoglobin final value during VHI exercise was higher than during HVY and MOD exercise (∼90% of HHb physiological normalization, vs. ∼82% HVY and ∼45% MOD). The muscle fatigue was greater after VHI exercise (∼22% vs. HVY ∼5%). There was no muscle fatigue after MOD exercise. The greatest magnitude of muscle fatigue occurred within 2 min (VHI ∼17%; HVY ∼9%), after which it stabilized. No significant relationship between V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ and muscle force production was observed. The τ of muscle V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ was significantly related (R2  = 0.47) with torque decrease for VHI. Type I and II muscle fibre recruitment mainly in the rectus femoris moderately explained the muscle fatigue (R2  = 0.30 and 0.31, respectively) and the V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ (R2  = 0.39 and 0.27, respectively). The V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ is also partially explained by blood lactate accumulation (R2  = 0.42). In conclusion muscle fatigue and O2 cost seem to share the same physiological cause linked with a decrease in the muscle V ̇ O 2 ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ and a change in lactate accumulation. Muscle fatigue and V ̇ O 2 sc ${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ are associated with muscle activation heterogeneity and metabolism of different muscles activated during cycling.

External Loads of Elite Soccer Referees: A Systematic Review with meta-analysis.

The objective of the present study was to describe the total and fragmented external loads, at different intensities, of soccer referees in European and South American competitions during official matches through a systematic review and meta-analysis of cross-sectional studies. A systematic review was conducted in April, 2020. In all, 32 studies were included, incorporating 578 referees evaluated in 3170 games through video analysis or a global positioning system. Regarding external loads, it was observed that the total average distance covered by the referees was 10,461.74 m, with running speeds predominantly below 13 km.h-1. The total distance covered by the referees in the European competitions was higher and more intense than that of the referees in the South American tournaments, being 11,187.02 m and 9319.61 m, respectively. We suggest that referees' training can be organized according to the distances found at different intensities, in which low-intensity races can be performed below 13 km.h-1 with distances of approximately 4500 m, while high-intensity training can be developed with speeds from 18 to 24 km.h-1 for approximately 800 m. In addition, planning must consider the competition characteristics.

A novel treadmill protocol for uphill running assessment: the incline incremental running test (IIRT).

This study aimed to compare the maximal and submaximal aerobic parameters between two incremental running tests, one being horizontal and the other an incline-based test, namely the incline incremental running test (IIRT). Twenty endurance-trained trail runners completed two incremental treadmill tests, until exhaustion. The first test was performed using an incline of 1%, with speed increments. Then, the IIRT was performed with the speed set at 50% of the peak speed obtained during the previous test, and the incline was incremented. Cardiorespiratory measurements and blood lactate concentration ([La]) were assessed. The mean peak workload from the horizontal test was 17.6 ± 1.4 km.h-1 and peak workload from IIRT was 17.3 ± 1.3% of incline. The VO2peak and [La]peak were not significantly different between the protocols. However, the HRpeak was significantly lower at IIRT. In conclusion, most of the maximal and submaximal aerobic indices showed no differences between the incremental tests analysed. The exceptions were the HRpeak and HR at the lactate turnpoints, that were lower, and the peak O2 pulse that was greater for the IIRT. Taken together, these data support the validity of the IIRT as a specific test for the physiological assessment of runners involved with uphill performances.

W' reconstitution rate at different intensities above critical torque: the role of muscle size and maximal strength.

NEW FINDINGS: What is the central question of this study? Do muscle size, maximal force and exercise intensity influence the recovery time constant for the finite impulse above critical torque (τIET' )? What is the main finding and its importance? Muscle size and maximal strength have different influences on the parameters of the hyperbolic torque-time to task failure relationship. Greater muscle size and maximal strength, as well as exercise at an intensity of 60% MVC, prolong τIET' during intermittent isometric exercise. ABSTRACT: Muscle perfusion and O2 delivery limitations through muscle force generation appear to play a major role in defining the hyperbolic torque-time to task failure (Tlim ) relationship. Therefore, we aimed to determine the influence of muscle size and maximal strength on the recovery time constant for the finite impulse above critical torque (τIET' ). Ten men participated in the study and performed intermittent isometric tests until task-failure (Tlim ) for the knee-extensors (KE) (35% and 60% maximal voluntary contraction (MVC)) and plantar flexors (PF) (60% MVC). The τIET' was determined for each of these Tlim tests using the IET'BAL model. The IET' (9738 ± 3080 vs. 2959 ± 1289 N m s) and end-test torque (ET)(84.5 ± 7.1 vs. 74.3 ± 12.7 N m) were significantly lower for PF compared to KE (P < 0.05). Exercise tolerance (Tlim ) was significantly longer for PF (239 ± 81 s) than KE (150 ± 55 s) at 60% MVC, and significantly longer for KE at 35% MVC (641 ± 158 s) than 60% MVC. The τIET' was significantly faster at 35% MVC (641 ± 177 s) than 60% MVC (1840 ± 354 s) for KE, both of which were significantly slower than PF at 60% MVC (317 ± 102 s). This study showed that τIET' during intermittent isometric exercise is slower with greater muscle size and maximal strength.

Moving forward with backward pedaling: a review on eccentric cycling.

PURPOSE: There is a profound gap in the understanding of the eccentric cycling intensity continuum, which prevents accurate exercise prescription based on desired physiological responses. This may underestimate the applicability of eccentric cycling for different training purposes. Thus, we aimed to summarize recent research findings and screen for possible new approaches in the prescription and investigation of eccentric cycling. METHOD: A search for the most relevant and state-of-the-art literature on eccentric cycling was conducted on the PubMed database. Literature from reference lists was also included when relevant. RESULTS: Transversal studies present comparisons between physiological responses to eccentric and concentric cycling, performed at the same absolute power output or metabolic load. Longitudinal studies evaluate responses to eccentric cycling training by comparing them with concentric cycling and resistance training outcomes. Only one study investigated maximal eccentric cycling capacity and there are no investigations on physiological thresholds and/or exercise intensity domains during eccentric cycling. No study investigated different protocols of eccentric cycling training and the chronic effects of different load configurations. CONCLUSION: Describing physiological responses to eccentric cycling based on its maximal exercise capacity may be a better way to understand it. The available evidence indicates that clinical populations may benefit from improvements in aerobic power/capacity, exercise tolerance, strength and muscle mass, while healthy and trained individuals may require different eccentric cycling training approaches to benefit from similar improvements. There is limited evidence regarding the mechanisms of acute physiological and chronic adaptive responses to eccentric cycling.

Creatine supplementation attenuates the rate of fatigue development during intermittent isometric exercise performed above end-test torque.

NEW FINDINGS: What is the central question of this study? Does creatine supplementation augment the total torque impulse accumulated above end-test torque (IET) during severe-intensity knee-extensor exercise by attenuating the rate of decrease in peak potentiated twitch torque (PT)? What is the main finding and its importance? Creatine augmented the IET and attenuated the rate of decrease in both voluntary activation and PT during severe-intensity exercise. The IET was related to the rate of decrease in PT. These findings reveal an important role for the rates of neuromuscular fatigue development as key determinants of exercise tolerance within the severe domain. ABSTRACT: This study investigated the effect of creatine supplementation on exercise tolerance, total torque impulse accumulated above end-test torque (total IET) and neuromuscular fatigue development of the knee extensors during severe-intensity intermittent isometric exercise. Sixteen men were randomly allocated into Creatine (n = 8, 20 g day-1 for 5 days) or Placebo (n = 8) groups and performed knee-extensor maximal voluntary contraction (MVC) testing, all-out testing to determine end-test torque (ET) and the finite torque impulse accumulated above end-test torque (IET'), and three submaximal tests at ET + 10%: (i) time to task failure without supplementation (Baseline); (ii) time to task failure after creatine or placebo supplementation; and (iii) time matched to Baseline after creatine (Creatine-Isotime) or placebo (Placebo-Isotime) supplementation. Creatine supplementation significantly increased the time to task failure (Baseline = 572 ± 144 s versus Creatine = 833 ± 221 s) and total IET (Baseline = 5761 ± 1710  N m s versus Creatine = 7878 ± 1903 N m s), but there were no significant differences within the Placebo group. The percentage change pre- to postexercise in MVC, voluntary activation, peak potentiated twitch torque and integrated EMG during MVC were not significantly different between Baseline and Creatine but were all significantly attenuated in Creatine-Isotime compared with Baseline. There were no significant differences in these variables within the placebo group. The total IET was significantly correlated with the rates of change in potentiated twitch torque peak (r = 0.83-0.87) and rate of torque development (r = -0.83 to -0.87) for the submaximal tests to task failure. These findings reveal an important role for the rates of neuromuscular fatigue development as key determinants of exercise tolerance during severe-intensity intermittent isometric exercise.

Effects of resistance training on impulse above end-test torque and muscle fatigue.

NEW FINDINGS: What is the central question of this study? What role do neuromuscular fatigue mechanisms play in resistance training-induced adaptations of the impulse above end-test torque (IET) after the training period? What is the main finding and its importance? IET and global and peripheral fatigue were increased after a short period of resistance training. Thus, resistance training-induced adaptations in neuromuscular fatigue seem to contribute to enhanced IET after the training period. ABSTRACT: Short-term resistance training has a positive influence on the curvature constant of the power-duration relationship (W'). The physiological mechanism of W' enhancement after resistance training is unclear. This study aimed to determine whether one-leg maximal isometric resistance training influences (1) impulse above end-test torque (IET; an analogue of W') during a 5 min all-out isometric test; and (2) exercise tolerance (limit of tolerance, Tlim) and neuromuscular fatigue during severe exercise (i.e. above end-test torque; ET). Sixteen healthy active males participated in a 3-week unilateral knee extensor resistance-training programme, and 10 matched subjects participated as controls. The subjects were instructed to ramp up to 100% of maximal voluntary contraction (MVC) over 1 s, hold it for 3 s, and relax. Each repetition had a 2 s interval (10) and each set, a 2 min interval (3). MVC (18.6%) and muscle thickness (12.8%) were significantly improved after training. Significantly greater global (i.e. reduced MVC, 43.2 ± 13.5% vs. 58.9 ± 6.9%) and peripheral (51.7 ± 13.6% vs. 57.3 ± 15.3%) fatigue, IET (26%) and Tlim (92%) were obtained after resistance training. Moreover, both global (r = 0.57, P < 0.05) and peripheral fatigue (r = 0.55, P < 0.05) accrued during severe exercise were associated with IET. However, echo intensity, which reflects muscle quality, ET and central fatigue remained unchanged throughout the training period. No significant changes in the control group for any variable were observed. Resistance training-induced adaptations in muscle size and neuromuscular fatigue seem to contribute to enhanced IET and Tlim after the training period.

Rate of utilization of a given fraction of W' (the curvature constant of the power-duration relationship) does not affect fatigue during severe-intensity exercise.

NEW FINDINGS: What is the central question of this study? Does the rate of utilization of W' (the curvature constant of the power-duration relationship) affect fatigue during severe-intensity exercise? What is the main finding and its importance? The magnitude of fatigue after two severe-intensity exercises designed to deplete the same fraction of W' (70%) at two different rates of utilization (fast versus slow) was similar after both exercises. Moreover, the magnitude of fatigue was related to critical power (CP), supporting the contention that CP is a key determinant in fatigue development during high-intensity exercise. Thus, the CP model is a suitable approach to investigate fatigue mechanisms during high-intensity exercise. The depletion of W' (the curvature constant of the power-duration relationship) seems to contribute to fatigue during severe-intensity exercise. Therefore, the aim of this study was to determine the effect of a fast versus a slow rate of utilization of W' on the occurrence of fatigue within the severe-intensity domain. Fifteen healthy male subjects performed tests to determine the critical power, W' and peak torque in the control condition (TCON ) and immediately after two fatiguing work rates (THREE and TEN) set to deplete 70% W' in either 3 (TTHREE ) or 10 min (TTEN ). The TTHREE and TTEN were significantly reduced (F = 19.68, P = 0.01) in comparison to TCON . However, the magnitude of reduction in peak torque (TTHREE  = -19.8 ± 10.1% versus TTEN  = -16.8 ± 13.3%) was the same in the two fatiguing exercises (t = -0.76, P = 0.46). There was a significant inverse relationship between the critical power and the reduction in peak torque during both THREE (r = -0.49, P = 0.03) and TEN (r = -0.62, P = 0.02). In contrast, the W' was not significantly correlated with the reduction in peak torque during both THREE (r = -0.14, P = 0.33) and TEN (r = -0.30, P = 0.10). Thus, fatigue following severe-intensity exercises performed at different rates of utilization of W' was similar when the same work was done above the critical power (i.e. same amount of W' used).

The effect of prior exercise intensity on oxygen uptake kinetics during high-intensity running exercise in trained subjects.

PURPOSE: The aim of this study was to compare the effects of two different kinds of prior exercise protocols [continuous exercise (CE) versus intermittent repeated sprint (IRS)] on oxygen uptake (VO2) kinetics parameters during high-intensity running. METHODS: Thirteen male amateur futsal players (age 22.8 ± 6.1 years; mass 76.0 ± 10.2 kg; height 178.7 ± 6.6 cm; VO2max 58.1 ± 4.5 mL kg(-1) min(-1)) performed a maximal incremental running test for the determination of the gas exchange threshold (GET) and maximal VO2 (VO2max). On two different days, the subjects completed a 6-min bout of high-intensity running (50 % ∆) on a treadmill that was 6-min after (1) an identical bout of high-intensity exercise (from control to CE), and (2) a protocol of IRS (6 × 40 m). RESULT: We found significant differences between CE and IRS for the blood lactate concentration ([La]; 6.1 versus 10.7 mmol L(-1), respectively), VO2 baseline (0.74 versus 0.93 L min(-1), respectively) and the heart rate (HR; 102 versus 124 bpm, respectively) before the onset of high-intensity exercise. However, both prior CE and prior IRS significantly increased the absolute primary VO2 amplitude (3.77 and 3.79 L min(-1), respectively, versus control 3.54 L min(-1)), reduced the amplitude of the VO2 slow component (0.26 and 0.21 L min(-1), respectively, versus control 0.50 L min(-1)), and decreased the mean response time (MRT; 28.9 and 28.0 s, respectively, versus control 36.9 s) during subsequent bouts. CONCLUSION: This study showed that different protocols and intensities of prior exercise trigger similar effects on VO2 kinetics during high-intensity running.

Isokinetic eccentric resistance training prevents loss in mechanical muscle function after running.

The aim of the study was to verify whether 8 weeks of resistance training employing maximal isokinetic eccentric (IERT) knee extensor actions would reduce the acute force loss observed after high-intensity treadmill running exercise. It was hypothesized that specific IERT would induce protective effects against muscle fatigue and ultrastructural damages, preventing or reducing the loss in mechanical muscle function after running. Subjects were tested before and after IERT protocol for maximal isometric, concentric and eccentric isokinetic knee extensor strength (60° and 180° s(-1)). In a second session, subjects performed treadmill running (~35 min) and the previously mentioned measurements were repeated immediately after running. Subsequently, subjects were randomized to training (n = 12) consisting of 24 sessions of maximal IERT knee extensors actions at 180° s(-1), or served as controls (n = 8). The effects of acute running-induced fatigue and training on isokinetic and isometric peak torque, and rate of force development (RFD) were investigated. Before IERT, running-induced eccentric torque loss at 180° s(-1) was -8 %, and RFD loss was -11 %. Longitudinal IERT led to reduced or absent acute running-induced losses in maximal IERT torque at 180° s(-1) (+2 %), being significantly reduced compared to before IERT (p < 0.05), however, RFD loss remained at -11 % (p > 0.05). In conclusion, IERT yields a reduced strength loss after high-intensity running workouts, which may suggest a protective effect against fatigue and/or morphological damages. However, IERT may not avoid reductions in explosive muscle actions. In turn, this may allow more intense training sessions to be performed, facilitating the adaptive response to running training.

Exercise-induced muscle damage and running economy in humans.

Running economy (RE), defined as the energy demand for a given velocity of submaximal running, has been identified as a critical factor of overall distance running performance. Plyometric and resistance trainings, performed during a relatively short period of time (~15-30 days), have been successfully used to improve RE in trained athletes. However, these exercise types, particularly when they are unaccustomed activities for the individuals, may cause delayed onset muscle soreness, swelling, and reduced muscle strength. Some studies have demonstrated that exercise-induced muscle damage has a negative impact on endurance running performance. Specifically, the muscular damage induced by an acute bout of downhill running has been shown to reduce RE during subsequent moderate and high-intensity exercise (>65% VO2max). However, strength exercise (i.e., jumps, isoinertial and isokinetic eccentric exercises) seems to impair RE only for subsequent high-intensity exercise (~90% VO2max). Finally, a single session of resistance exercise or downhill running (i.e., repeated bout effect) attenuates changes in indirect markers of muscle damage and blunts changes in RE.

Does creatine supplementation affect recovery speed of impulse above critical torque?

We previously reported that creatine supplementation improved intermittent isometric exercise performance by augmenting the total impulse performed above end-test torque (total IET'). However, our previous analyses did not enable mechanistic assessments. The objective of this study was to determine if creatine supplementation affected the IET' speed of recovery. To achieve this objective, we retrospectively analyzed our data using the IET' balance model to determine the time constant for the recovery of IET' (τIET'). Sixteen men were randomly allocated into creatine (N = 8) or placebo (N = 8) groups. Prior to supplementation, participants performed quadriceps all-out exercise to determine end-test torque (ET) and IET'. Participants then performed quadriceps exercise at ET + 10% until task-failure before supplementation (Baseline), until task-failure after supplementation (Creatine or Placebo), and until the Baseline time after supplementation (Creatine- or Placebo-Isotime). τIET' was faster than Baseline for Creatine (669 ± 98 vs 470 ± 66 s), but not Placebo (792 ± 166 vs 786 ± 161 s). The creatine-induced change in τIET' was inversely correlated with the creatine-induced changes in both the rate of peripheral fatigue development and time to task-failure. τIET' was inversely correlated with total IET' and ET in all conditions, but creatine supplementation shifted this relationship such that τIET' was faster for a given ET. Creatine supplementation, therefore, sped the recovery of IET' during intermittent isometric exercise, which was inversely related to the improvement in exercise performance. These findings support that the improvement in exercise performance after creatine supplementation was, at least in part, specific to effects on the physiological mechanisms that determine the IET' speed of recovery.HIGHLIGHTSSixteen healthy participants were randomly allocated to creatine supplementation or placebo groups.Creatine supplementation accelerated the time constant for the recovery of IET' (τIET').The time constant for the recovery of IET' (τIET') was inversely related to both the rate of peripheral fatigue development and the time to task failure.

Effects of Loaded Plyometric Exercise on Post-Activation Performance Enhancement of Countermovement Jump in Sedentary Men.

Purpose: Explosive performance is increased right after performing loaded resistance exercise, which is known as post-activation performance enhancement (PAPE). Method: We investigated the effects of a plyometric exercise (PLYO) consisting of five sets of six drop-jumps from a 52-cm platform with a load corresponding to 20% body mass on changes in countermovement jump (CMJ) height in sedentary young men. Eleven young nonresistance trained men (19.6 ± 1.8 y, 69 ± 9 kg, 1.76 ± 0.08 m) who showed more than 4% increase in CMJ height at 4 min after five back squats with five-repetition maximum load participated in the study. Their responses to the back squat exercise were examined before (baseline) and 15 minutes, 24 and 48 hours post-PLYO. Exercise-induced muscle damage markers (maximal voluntary contraction torque [MVC], and quadriceps muscle soreness) were assessed at baseline, 15 minutes, 24 and 48 hours following PLYO. Results: MVC torque decreased (p < .05) at 15 minutes post-PLYO (-15.1 ± 9.7%) but returned to the baseline at 24 hours post-PLYO. Muscle soreness developed (p < .05) at 48 hours (21.0 ± 20.3 mm) after PLYO, indicating minor muscle damage. CMJ height increased (p < .05) after the five squats at baseline (7.6 ± 3.8%) indicating PAPE, but no such increase was found at 15 minutes, 24 and 48 hours after PLYO. However, CMJ height before the squat exercise was greater (p < .05) at 24 (5.9 ± 7.0%) and 48 hours post-PLYO (9.1 ± 8.5%) than the baseline. Conclusions: These results showed that PAPE disappeared after PLYO that induced minor muscle damage, but CMJ height increased at 24-48 hours in the recovery from PLYO exhibiting a priming effect.

Chronic Adaptations to Eccentric Cycling Training: A Systematic Review and Meta-Analysis.

This study aimed to investigate the effects of eccentric cycling (ECCCYC) training on performance, physiological, and morphological parameters in comparison to concentric cycling (CONCYC) training. Searches were conducted using PubMed, Embase, and ScienceDirect. Studies comparing the effect of ECCCYC and CONCYC training regimens on performance, physiological, and/or morphological parameters were included. Bayesian multilevel meta-analysis models were used to estimate the population's mean difference between chronic responses from ECCCYC and CONCYC training protocols. Group levels and meta-regression were used to evaluate the specific effects of subjects and study characteristics. Fourteen studies were included in this review. The meta-analyses showed that ECCCYC training was more effective in increasing knee extensor strength, vastus lateralis fiber cross-sectional area, and six-minute walking distance compared to CONCYC. Moreover, ECCCYC was as effective as CONCYC in decreasing body fat percentage. CONCYC was more effective in increasing V˙O2max and peak power output attained during concentric incremental tests. However, group-level analyses revealed that ECCCYC was more effective than CONCYC in improving V˙O2max in patients with cardiopulmonary diseases. ECCCYC is a viable modality for exercise interventions aiming to improve parameters of muscle strength, hypertrophy, functional capacity, aerobic power, and body composition, with more advantages than CONCYC training in improving neuromuscular variables.

Post-activation performance enhancement does not occur following a large hand-paddles and parachute-resisted warm-up routine in collegiate swimmers.

Our aim was to investigate if using a warm-up routine that included parachute-resisted sprints with large hand-paddles improves 50 m freestyle performance in trained collegiate swimmers. Twelve swimmers (23.9 ± 2.2 years, 179 ± 7 cm, 77.1 ± 10.6 kg) participated in the study and completed two 50-m freestyle races, each preceded by a different warm-up routine, either control (CON) or experimental (EXP). The warm-up routines consisted of 500 m of swimming at self-selected speed, followed by four 10 s sprints with 1 min rest intervals. During EXP, sprints were performed using large hand-paddles and a swimming parachute, while during CON, sprints were performed freely. Performance and technique were assessed during the 50 m freestyle races. We found no significant differences in 25- and 50 m performance times (CON: 12.6 ± 0.8 vs. EXP: 12.5 ± 0.8 s, ES = 0.125; and CON: 26.8 ± 1.6 vs. EXP: 26.7 ± 1.7 s, ES = 0.06, respectively) between the two conditions. Mean stroke length (CON: 2.04 ± 0.21 vs. EXP: 2.02 ± 0.22 m·cycle-1, ES = 0.09), stroke frequency (CON: 55.4 ± 5.3 vs. EXP: 56.3 ± 5.2 cycles s-1, ES = 0.17), and propulsive time (CON: 0.62 ± 0.07 vs. EXP: 0.61 ± 0.06 s, ES = 0.15) were also not different between conditions. It is possible that the CON warm-up routine induced the priming effects that lead to PAPE, or that the EXP warm-up routine primed the athletes further but also induced greater fatigue, resulting in no significant effects on swimming performance. Our findings suggest that parachute-resisted sprints with hand-paddles during warm-up do not enhance 50 m freestyle swimming performance in trained collegiate swimmers. Coaches and practitioners should consider exploring different warm-up protocols to identify what works best for their athletes.