Detalhe da pesquisa
1.
Evaluation of in vitro antiviral activity of SARS-CoV-2 Mpro inhibitor pomotrelvir and cross-resistance to nirmatrelvir resistance substitutions.
Antimicrob Agents Chemother
; 67(11): e0084023, 2023 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37800975
2.
An mRNA Vaccine against SARS-CoV-2 - Preliminary Report.
N Engl J Med
; 383(20): 1920-1931, 2020 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32663912
3.
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults.
N Engl J Med
; 383(25): 2427-2438, 2020 12 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32991794
4.
Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness.
J Virol
; 96(16): e0084122, 2022 08 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35924922
5.
The coronavirus proofreading exoribonuclease mediates extensive viral recombination.
PLoS Pathog
; 17(1): e1009226, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33465137
6.
Reovirus RNA recombination is sequence directed and generates internally deleted defective genome segments during passage.
J Virol
; 95(8)2021 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33472930
7.
Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit.
J Infect Dis
; 224(Supplement_1): S1-S21, 2021 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34111271
8.
Fitness Barriers Limit Reversion of a Proofreading-Deficient Coronavirus.
J Virol
; 93(20)2019 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31341046
9.
Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance.
J Virol
; 93(24)2019 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31578288
10.
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc Natl Acad Sci U S A
; 114(35): E7348-E7357, 2017 08 29.
Artigo
Inglês
| MEDLINE | ID: mdl-28807998
11.
Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination.
N Engl J Med
; 384(1): 80-82, 2021 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33270381
12.
Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity.
J Virol
; 92(1)2018 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29046453
13.
Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J Virol
; 92(10)2018 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29514901
14.
Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
J Virol
; 90(16): 7248-7256, 2016 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27252528
15.
Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.
J Virol
; 90(16): 7415-7428, 2016 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27279608
16.
Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.
J Virol
; 90(21): 9683-9692, 2016 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27535047
17.
Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
J Biol Chem
; 290(32): 19403-22, 2015 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26055715
18.
Mutations across murine hepatitis virus nsp4 alter virus fitness and membrane modifications.
J Virol
; 89(4): 2080-9, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25473044
19.
Serotonin Receptor Agonist 5-Nonyloxytryptamine Alters the Kinetics of Reovirus Cell Entry.
J Virol
; 89(17): 8701-12, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26109733
20.
Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.
J Virol
; 89(12): 6418-26, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25855750