Assuntos
Impressões Digitais de DNA/métodos , Frequência do Gene/genética , Repetições de Microssatélites/genética , Polimorfismo Genético , População Branca/genética , Alelos , Manchas de Sangue , Feminino , Genes Dominantes/genética , Marcadores Genéticos/genética , Genética Populacional , Humanos , Masculino , Polônia , Reação em Cadeia da Polimerase/métodos , Valores de ReferênciaRESUMO
Allele and haplotype frequencies of nine Y-chromosome STR loci were determined from a sample of 508 unrelated males from north Poland. Three samples containing insertion polymorphism DYS19 (duplication) and DYS385I/II (triplications) were observed.
Assuntos
Cromossomos Humanos Y , Frequência do Gene , Genética Populacional , Haplótipos , Sequências de Repetição em Tandem , Impressões Digitais de DNA/métodos , Humanos , Masculino , Polônia , Polimorfismo GenéticoRESUMO
This paper describes the polymorphism of a YCAII locus in a Polish population sample of 189 males. In an analyzed population sample 6 of 11 alleles identified to date were found (www.ystr.org). The most frequent allele was 19 with a frequency of 0.4343. The calculated gene diversity value for YCAII locus is 0.62 and possesses a rather moderate discrimination power for loci analyzed in our population to date. Comparison of homogeneity distribution of YCAII alleles between different populations was analyzed. Very significant statistical differences (p<0.0000) were observed between our population and Italian, German, Lithuanian, Latvian and Estonian populations. No statistical differences were observed between the Polish and Slovenian population sample (p=0.40).
Assuntos
Cromossomos Humanos Y/genética , Polimorfismo Genético , Sequências de Repetição em Tandem/genética , Adulto , Impressões Digitais de DNA/métodos , Medicina Legal , Frequência do Gene , Marcadores Genéticos , Genética Populacional , Humanos , Masculino , Polônia/epidemiologiaRESUMO
This paper describes the polymorphism of a new locus DYS439 in a Polish population sample of 198 males. To correctly type DYS439 alleles, a sequenced allelic ladder was constructed. In an analyzed population sample 6 of 7 alleles identified to date were found (17, 19-23). The most frequent allele was 19 with a frequency of 0.4343. Calculated gene diversity value for DYS439 locus is 0.70 and is one of the highest for Y-STR loci analyzed in our population to date. Moreover a comparison of homogeneity distribution of DYS 439 alleles between different populations was analyzed. Very significant statistical differences (p < 0.0000) were observed between our population and four European population samples (Italy, Portugal and Spain).
Assuntos
Cromossomos Humanos Y/genética , Impressões Digitais de DNA/métodos , Polimorfismo Genético , Sequências de Repetição em Tandem/genética , Adulto , Alelos , Genética Populacional , Humanos , Itália , Masculino , Polônia , Portugal , EspanhaRESUMO
This paper describes polymorphism of a new locus DYS438 in a Polish population sample of 249 males. In an analyzed population sample 5 of 9 alleles, to date identified, were found (6-14). The most frequent allele was 11 with a frequency of 0.5502. In our population bimodal frequency distribution of DYS438 alleles contrary to the other European populations was not observed. The calculated gene diversity value for DYS438 locus is 0.53 and is higher than observed for DYS391, DYS3891, DYS392 i DYS393 and lower than observed for DYS385I/II, DYS19, DYS389II, DYS439 i DYS390 Y-STR loci analyzed to date in our population. Moreover comparison of homogeneity distribution of DYS438 alleles between different populations was analyzed. Very significant statistical differences (p < 0.0000) were observed between our population and three other European population samples (Italy, Portugal, Spain and Denmark).