Influence of stimuli emotional features and typicality on memory performance: insights from a virtual reality context.

The present study tested the influence of stimuli emotional valence, emotional arousal, and typicality on memory recollection in three groups of participants exposed to the same environment through different modalities: in vivo exposure (i.e., real-life), 3D virtual reality (i.e., VR), and 2D pictures. Context-related free-recall, recognition accuracy, and recognition confidence were analyzed. The results showed that memory performance was best in the real-life modality, and participants in the VR and 2D pictures modalities performed comparably. Interesting effects of stimuli emotional valence and typicality emerged: in the VR and 2D pictures modalities, positive items were better recalled than negative items; typicality was relevant only in the real-life modality, with less common objects within the explored setting (i.e., an office) recalled more often. Furthermore, recognition accuracy and confidence were significantly higher in the real-life modality than in the VR and 2D pictures modalities. Further research is needed to support the creation of VR environments that are sufficiently comparable to real-life contexts in order to obtain higher ecological validity in studies of cognitive performance. In particular, the impact of stimuli typicality and emotional valence in VR contexts should be investigated to gain insight into how these features might improve memory recall in virtual scenarios.

Age-related differences on temporal source memory by using dynamic stimuli: the effects of POV and emotional valence.

Previous studies have highlighted that temporal source memory can be influenced by factors such as the individual's age and the emotional valence of the event to be remembered. In this study, we investigated how the different points of view (POVs) from which an event is presented could interact with the relationship between age-related differences and emotional valence on temporal source memory. One hundred and forty-one younger adults (aged 18-30) and 90 older adults (aged 65-74) were presented with a series of emotional videos shot from different POVs (first vs. third-person) in three sessions. In the fourth session, participants were asked to indicate in which session (1, 2, or 3) they viewed each video. The results indicated that the first-person POV amplified the effects of the emotional valence on temporal source memory. Only in this experimental condition, older adults "pushed away" negative stimuli by perceiving them as more distant in time, and "kept closer" positive stimuli by perceiving them as more recent. In comparison, younger adults "kept closer" positive stimuli. These findings add to the existing literature on the positivity effect on temporal source memory and highlighted the importance of considering the POV in relation to the emotional valence.

Time reproduction, bisection and doubling: a novel paradigm to investigate the effect of the internal clock on time estimation.

Time perception is not always veridical, but it can be modulated by changes in internal and external context. The most-acknowledged theory in this regard hypothesises the existence of an internal clock allowing us to subjectively estimate time intervals. The aim of the present study is to investigate the possible effect of such an internal clock, measured as the ability to reproduce a target duration, in the mental manipulation of time: 63 healthy participants were asked to Bisect and to Double reference time intervals, besides Reproducing them. Moreover, to investigate whether time processing might be predicted by individual differences, handedness, anxiety, and personality traits were also assessed by means of standardized questionnaires. Results show that participants correctly Reproduce time intervals (internal clock), but they overestimate time intervals during Bisection and underestimate them during Doubling. We explain this unexpected pattern of results as a kind of aftereffect, due to the short-term retention (adaptation) to the subjective representation of shorter (Bisection) vs longer (Doubling) intervals, respectively. Moreover, hierarchic regression models reveal that some personality traits can predict Bisection accuracy, but they clearly show that the best predictor for both Bisection and Doubling is the accuracy in Reproducing time intervals, confirming the fundamental role of the internal clock in time estimation. We conclude that time estimation is a unique skill, mostly independent from inter-individual differences, and the new paradigms introduced here (bisection vs doubling) reveal that the correct functioning of the internal clock also explains the ability to mentally manipulate the time.

The effect of aging and emotions on time processing.

BACKGROUND: Time perception is an automatic process that can be influenced by intrinsic and extrinsic factors. AIMS: This study aimed to investigate the effect of age and emotions on the ability to keep track of short suprasecond intervals. METHODS: Younger adults (N = 108, age range: 18-35) and older adults (N = 51, age range: 65-87) were asked to reproduce, bisect, or double the duration of facial stimuli randomly presented for 1500, 3000, and 4500 ms. The experiment included facial stimuli with positive, negative, or neutral expressions. RESULTS: The participants across age correctly reproduced intervals but overestimated and underestimated them when asked to bisect and double the intervals, respectively. Overall, when faces were presented with a positive or negative expression, an overestimation of time intervals emerged compared to faces with neutral expressions. Emotions had a greater effect on older adults, who showed a greater overestimation of positive facial expressions and an underestimation of sad, but not angry, facial expressions. DISCUSSION: The results provide evidence that time perception is influenced by age and emotions, with older adults showing a greater effect of emotions on time processing. CONCLUSION: The study suggests an interaction among time processing, age, and emotions, highlighting an automatic relationship among these domains, often considered independent.

How emotions induced by reading influence sleep quality in young and older adults.

OBJECTIVES: This study examined whether emotions induced by reading before sleep influence sleep quality in young and older adults. METHOD: Sixty older adults (64-75 years) and 60 young adults (18-35 years) were randomly assigned to three conditions: positive reading, neutral reading, and control. The reading groups read a short story at bedtime, whereas the control group kept its routine. Participants completed measures of affective states, subjective sleep parameters, and self-reported sleep quality related to emotions over 7 consecutive days. RESULTS: Older adults reported much longer sleep latency and lower sleep efficiency than young adults. In both reading conditions, older adults reported reduced sleep latencies compared to the control group. In the positive reading condition, older adults reported an increased sleep duration compared to younger adults and the other conditions. Young and older adults in the positive condition showed better self-reported sleep quality than those in the neutral conditions, regardless of age. CONCLUSIONS: Reading at bedtime appears to reduce older adults' time to fall asleep and increase their sleep duration. Positive emotions induced by reading short stories at bedtime seem to be a sleep-promoting factor that improves bedtime and wake time in young and older adults.

Phase-dependent local brain states determine the impact of image-guided transcranial magnetic stimulation on motor network electroencephalographic synchronization.

Recent studies have synchronized transcranial magnetic stimulation (TMS) application with pre-defined brain oscillatory phases showing how brain response to perturbation depends on the brain state. However, none have investigated whether phase-dependent TMS can possibly modulate connectivity with homologous distant brain regions belonging to the same network. In the framework of network-targeted TMS, we investigated whether stimulation delivered at a specific phase of ongoing brain oscillations might favour stronger cortico-cortical (c-c) synchronization of distant network nodes connected to the stimulation target. Neuronavigated TMS pulses were delivered over the primary motor cortex (M1) during ongoing electroencephalography recording in 24 healthy individuals over two repeated sessions 1 month apart. Stimulation effects were analysed considering whether the TMS pulse was delivered at the time of a positive (peak) or negative (trough) phase of µ-frequency oscillation, which determines c-c synchrony within homologous areas of the sensorimotor network. Diffusion weighted imaging was used to study c-c connectivity within the sensorimotor network and identify contralateral regions connected with the stimulation spot. Depending on when during the µ-activity the TMS-pulse was applied (peak or trough), its impact on inter-hemispheric network synchrony varied significantly. Higher M1-M1 phase-lock synchronization after the TMS-pulse (0-200 ms) in the µ-frequency band was found for trough compared to peak stimulation trials in both study visits. Phase-dependent TMS delivery might be crucial not only to amplify local effects but also to increase the magnitude and reliability of the response to the external perturbation, with implications for interventions aimed at engaging more distributed functional brain networks. KEY POINTS: Synchronized transcranial magnetic stimulation (TMS) pulses with pre-defined brain oscillatory phases allow evaluation of the impact of brain states on TMS effects. TMS pulses over M1 at the negative peak of the µ-frequency band induce higher phase-lock synchronization with interconnected contralateral homologous regions. Cortico-cortical synchronization changes are linearly predicted by the fibre density and cross-section of the white matter tract that connects the two brain regions. Phase-dependent TMS delivery might be crucial not only to amplify local effects but also to increase the magnitude and reliability of within-network synchronization.

"When did you see it?" The effect of emotional valence on temporal source memory in aging.

Previous studies consistently showed age-related differences in temporal judgment and temporal memory. Importantly, emotional valence plays a crucial role in older adults' information processing. In this study, we examined the effects of emotions at the intersection between time and memory, analysing age-related differences in a temporal source memory task. Twenty-five younger adults (age range 18-35), 25 old adults (age range 65-74), and 25 old-old adults (age range 75-84) saw a series of emotional pictures in three sessions separated by a one-day rest period. In the fourth session, participants were asked to indicate in which session (1, 2, or 3) they saw each picture. Results showed that old-old adults tended to collocate negative pictures distant in time, while positive stimuli were remembered as more recent than real, compared to neutral pictures. To a lower extent, people over 65 showed the same pattern of results. In contrast, emotional valence did not affect younger adults' temporal positioning of stimuli. Current findings fit well with the Socio-Emotional Selectivity Theory's assumptions and extended the literature on the positivity effect to temporal source memory.

Automated Affective Computing Based on Bio-Signals Analysis and Deep Learning Approach.

Extensive possibilities of applications have rendered emotion recognition ineluctable and challenging in the fields of computer science as well as in human-machine interaction and affective computing. Fields that, in turn, are increasingly requiring real-time applications or interactions in everyday life scenarios. However, while extremely desirable, an accurate and automated emotion classification approach remains a challenging issue. To this end, this study presents an automated emotion recognition model based on easily accessible physiological signals and deep learning (DL) approaches. As a DL algorithm, a Feedforward Neural Network was employed in this study. The network outcome was further compared with canonical machine learning algorithms such as random forest (RF). The developed DL model relied on the combined use of wearables and contactless technologies, such as thermal infrared imaging. Such a model is able to classify the emotional state into four classes, derived from the linear combination of valence and arousal (referring to the circumplex model of affect's four-quadrant structure) with an overall accuracy of 70% outperforming the 66% accuracy reached by the RF model. Considering the ecological and agile nature of the technique used the proposed model could lead to innovative applications in the affective computing field.

Exploring vaccine hesitancy: the twofold role of critical thinking.

With the progress of the vaccination campaign against the SARS-COV-2, we are ever closer to reaching that part of the population that refuses or is hesitant about vaccination. This study investigated the association between critical thinking motivation factors (i.e., intrinsic value of critical thinking and expectancy of one's critical thinking ability), conspiracy mentality, intolerance of uncertainty and hesitancy toward vaccination. A sample of 390 participants completed an online survey during April 2021. Across participants, results indicate that conspiracy mentality and expectancy about personal ability as a critical thinker positively predict vaccine hesitancy. On the contrary, the intrinsic value attributed to critical thinking, intolerance of uncertainty, and education are negatively associated with hesitancy. While the findings confirm existing evidence, particularly on the detrimental role of conspiracy mentality on vaccine acceptance, they also shed light on the double-faced role exercised by critical thinking. Practical implications and future directions are discussed. Supplementary Information: The online version contains supplementary material available at 10.1007/s12144-022-04165-w.

Detecting faking-good response style in personality questionnaires with four choice alternatives.

Deliberate attempts to portray oneself in an unrealistic manner are commonly encountered in the administration of personality questionnaires. The main aim of the present study was to explore whether mouse tracking temporal indicators and machine learning models could improve the detection of subjects implementing a faking-good response style when answering personality inventories with four choice alternatives, with and without time pressure. A total of 120 volunteers were randomly assigned to one of four experimental groups and asked to respond to the Virtuous Responding (VR) validity scale of the PPI-R and the Positive Impression Management (PIM) validity scale of the PAI via a computer mouse. A mixed design was implemented, and predictive models were calculated. The results showed that, on the PIM scale, faking-good participants were significantly slower in responding than honest respondents. Relative to VR items, PIM items are shorter in length and feature no negations. Accordingly, the PIM scale was found to be more sensitive in distinguishing between honest and faking-good respondents, demonstrating high classification accuracy (80-83%).

Age-related differences in the perception of COVID-19 emergency during the Italian outbreak.

OBJECTIVES: Older adults have been identified as a high-risk population for COVID-19, therefore it is crucial to understand how they perceived and reacted to the emergency. We examined age-related differences in emotions, cognitive attitudes, and behavioral responses to the COVID-19 crisis. Based on the Socioemotional Selectivity Theory, we expected to find a positive approach in older adults, which may translate into lower compliance with restrictive measures.Methods: We analyzed data (n = 306) from a nation-wide online survey conducted between April 1st and April 16th, 2020. We compared young (18-29 years), middle-aged (30-50 years), and older (65-85 years) adults' self-reported emotions, attitudes toward the emergency, and compliance with governmental rules.Results: Older adults showed lower negative emotions than young and middle-aged adults. Also, older adults were more confident about COVID-related information received, more favorable toward the restrictive measures, and perceived lower underestimation of the emergency compared to the other age groups. However, older people anticipated a longer time for the emergency to resolve. No age-related differences in compliance with the rules emerged.Conclusion: Older people showed a positive attitude toward the emergency. This attitude was confined in the here and now and did not extend to expectations for the future. Compliance with rules was high across our sample. However, less compliant individuals were also less confident in COVID-related information received by the media and official sources, suggesting the importance of providing precise and reliable information to promote adherence to restrictive measures.

"What's next?" Individual differences in expected repercussions of the COVID-19 pandemic.

The effects of the COVID-19 pandemic on the future are hardly predictable, and people differ in terms of expected repercussions on their future. This study investigated individual differences in the pandemic's expected repercussions, with particular attention to a Balanced Time Perspective (BTP). BTP reflects an individual profile with optimal temporal orientations, it is positively associated with mental health, and it has proven to promote successful coping with unexpected crises. We analyzed data from 3991 adults from 18 to 85 years old participating in an online survey conducted during the Italian lockdown. Participants provided information on BTP, affective states, financial resources, and expectations for the future. Multi-group path analysis was used to test the hypothesized model and to explore gender differences. Results showed that people with a more BTP had fewer negative beliefs about COVID-19's consequences on their future life. BTP affected expected repercussions also indirectly, via affects and beliefs. Finally, gender emerged as a significant moderator of some of the relationships highlighted. The present study contributes to the understanding of the psychological reactions to the current health emergency by confirming its impact on several life domains besides health, not only in the present but also in the anticipated future.

Measuring global functioning in older adults with cognitive impairments using the Rasch model.

BACKGROUND: Cognitive and functional measures are often measured and interpreted separately during the clinical evaluation of patients with cognitive impairment. This can sometimes lead to a challenging interpretation when measures do not show concordance, especially after a clinical intervention. In this study, the development and evaluation of a new approach, using the Rasch model, that combines cognitive and functional measures in one single and more powerful measure (compared to stand-alone tests) to assess global functioning in older adults with cognitive impairment (including dementia) was presented. METHODS: Clinical data from 265 older adults' subjects diagnosed with mild cognitive impairment, or dementia, included: The Mini-mental state examination (MMSE), the Esame Neuropsicologico Breve (ENB) - a neuropsychological battery used in Italy-, the Activities of Daily Living (ADL), and the Instrumental Activities of Daily Living (IADL) questionnaires. RESULTS: Patients with severe cognitive impairment showed lower global functioning score compared to patients with moderate impairment. Receiver Operating Characteristic (ROC) curve analyses were performed to determine sensitivity and specificity of the global functioning score resulting from the combined measure. Results showed that the global functioning score discriminates better between patients with severe and moderate cognitive impairment compared to the ENB, ADL, and IADL when considered separately. CONCLUSIONS: The Rasch model was able to combine cognitive and functional measures into a single score (global functioning score). All together, these results suggest that the diverse cognitive and functional measures can be considered part of one single dimension (global functioning) and that this dimension can be measured as a single construct and score. This study offers an alternative perspective for future development of instruments that would help clinicians in measuring global functioning in older adults' patients at different stages of cognitive impairments and different baseline level of performance.

A variant on promoter of the cannabinoid receptor 1 gene (CNR1) moderates the effect of valence on working memory.

Cannabinoid receptor 1 gene (CNR1) variants have been related to affective information processing and, in particular, to stress release. Here, we aimed to examine whether the endocannabinoid system via CNR1 signaling modulates affective working memory, the memory system that transiently maintains and manipulates emotionally charged material. We focused on rs2180619 (A > G) polymorphism and examined genotype data collected from 231 healthy females. Analyses showed how a general positivity bias in working memory (i.e., better memory for positive words) emerged as task strings lengthened only in carriers of the major allele (AA/AG). Differently, GG carriers showed better memory for affective items in general (i.e., positive and negative words). These findings are some of the first to directly highlight the role of variant on promoter of the CNR1 gene in affective working memory and to evidence a differentiation among CNR1 genotypes in terms of larger difficulties in disengaging from negative stimuli in GG carriers.

When and where in aging: the role of music on source monitoring.

Difficulties in source monitoring (SM) tasks observed in healthy older adults may be linked to associative memory deficits since SM requires individuals to correctly bind and later remember these bound features to discriminate the origin of a memory. Therefore, focusing attention on discriminating factors that may attenuate older adults' difficulties in attributing contextual information to memories is necessary. We investigated the effect of affective information on source monitoring in younger and older adults by manipulating the type of affective information (pictures and music) and assessing the ability to remember spatial and temporal source details for affective pictures encoded while listening to classical music. Older and younger adults viewed a series of affective IAPS pictures presented on the left or right side of the computer screen in two different lists. At test, participants were asked to remember if the picture was seen (right/left), in which list (list1/list2) or whether it was new. Results showed that spatial information was attributed better than temporal information and emotional pictures were attributed better than neutral pictures in both younger and older adults. In addition, although music significantly increased source memory performance in both younger and older participants compared to the white noise condition, the pleasantness of music differentially affected memory for source details. The authors discuss findings in terms of an interaction between music, emotion and cognition in aging.

The modulating role of ADRA2B in emotional working memory: Attending the negative but remembering the positive.

Previous studies found that the ADRA2B gene modulates early perception and attention. Here, we aimed to examine whether ADRA2B polymorphisms also influence emotional working memory and the willingness to implement behaviors (switching affective intonation) in order to avoid negative information, both considered indexes of cognitive-affective flexibility. We examined genotype data collected from 212 healthy females, 91 ADRA2B carriers and 121 non-carriers, and found that carriers showed a positivity bias in working memory. That is, carriers remembered a higher number of positive words compared to negative and neutral words. In addition, although carriers were more unwilling to switch intonation in order to avoid negative information, they showed better recognition memory for words read with a positive intonation. These findings suggest that deletion variants of ADRA2B may show greater levels of cognitive-affective flexibility compared to non-carriers.

Facial Emotion Recognition in Bipolar Disorder and Healthy Aging.

Emotional face recognition is impaired in bipolar disorder, but it is not clear whether this is specific for the illness. Here, we investigated how aging and bipolar disorder influence dynamic emotional face recognition. Twenty older adults, 16 bipolar patients, and 20 control subjects performed a dynamic affective facial recognition task and a subsequent rating task. Participants pressed a key as soon as they were able to discriminate whether the neutral face was assuming a happy or angry facial expression and then rated the intensity of each facial expression. Results showed that older adults recognized happy expressions faster, whereas bipolar patients recognized angry expressions faster. Furthermore, both groups rated emotional faces more intensely than did the control subjects. This study is one of the first to compare how aging and clinical conditions influence emotional facial recognition and underlines the need to consider the role of specific and common factors in emotional face recognition.

Interference in Processing Agreement: The Impact of Grammatical Cues.

Agreement is a covariation in morphological form that reflects relations between words. A series of experiments were carried out in Italian during production and comprehension where an element interferes with agreement. The likelihood of interference found in both modalities is related to the markedness of the intervener and to its grammatical nature: it occurs more frequently when the number expressed on a prepositional modifiers intervene between the subject and the verb than the number expressed on an object pronoun. Furthermore, subject agreement process with an intervener object pronoun is prone to error, with many errors reported also in the matched condition and with slower reaction timing in comprehension. The study supports the idea that agreement is a grammatical process sensitive not only to the markedness of the intervener element but also to its structural position. A unifying explanation for agreement in both production and comprehension will be adopted in line with retrieval of an agreement source from a content-addressable memory sensitive to structural positions and their implementation in different languages.

Running with emotion: when affective content hampers working memory performance.

This study tested the hypothesis that affective content may undermine rather than facilitate working memory (WM) performance. To this end, participants performed a running WM task with positive, negative and neutral words. In typical running memory tasks, participants are presented with lists of unpredictable length and are asked to recall the last three or four items. We found that accuracy with affective words decreased as lists lengthened, whereas list length did not influence recall of neutral words. We interpreted this pattern of results in terms of a limited resource model of WM in which valence represents additional information that needs to be manipulated, especially in the context of difficult trials.

Virtual reality and cognitive rehabilitation for older adults with mild cognitive impairment: A systematic review.

Virtual Reality (VR) has been gaining increasing attention as a potential ecological and effective intervention system for treating Mild Cognitive Impairment (MCI). However, it remains unclear the efficacy and effectiveness of VR-based cognitive rehabilitation therapy (VR-CRT) in comparison with cognitive rehabilitation therapy (CRT). Consequently, a systematic review on Pubmed, Scopus, PsycInfo, and Web Of Science was conducted to assess the state of the art of the literature published between 2003 and April 2023. Only articles that adopted CRT as control group and that included some measure of at least one domain among overall cognitive function, executive function and functional status were included. Participants needed to be older adults aged 65 or over with a diagnosis of MCI. The risk of bias and the quality of evidence were assessed using the Version 2 of the Cochrane risk-of-bias tool for randomized trials. Initially, 6503 records were considered and screened after removing duplicates (n = 1321). Subsequently, 81 full texts were assessed for eligibility. Four articles met the inclusion criteria but 2 of them were merged as they were describing different outcomes of the same research project. Consequently, 3 overall studies with a total of 130 participants were included in the final analysis. Due to the high heterogeneity in the methodology and outcome measures employed, it was not possible to conduct a meta-analysis. Included studies used semi-immersive (k = 2) and full-immersive (k = 1) VR systems in their research. Two articles evaluated overall cognitive function through the MoCA together with specific tests for executive functions (n = 69), while one study adopted a comprehensive neuropsychological battery to evaluate both cognitive function and executive function (n = 61). Finally, one study evaluated functional status through instrumental activities of daily living (n = 34). A However, the limited number of studies, the small sample size, and the potential issues with the quality and methodology of these studies that emerged from the risk of bias assessment may raise doubts about the reliability of their results. Nevertheless, although scarce, results of the present review suggest that VR-CRT may be paramount in treating MCI for its additional ecological and adaptive advantages, as all of the studies highlighted that it was at least as effective as conventional CRT for all the outcome measures. Therefore, more rigorous research that compares VR-CRT and CRT is needed to understand the degree to which VR-CRT is effective with older adults with MCI and the potential role of immersion to influence its efficacy. Indeed, these preliminary findings highlight the need for the development of standardized VR protocols, as the integration of such technology into clinical practice may help improve the quality of life and cognitive outcomes for this growing demographic.