Detalhe da pesquisa
1.
A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.
Cell
; 165(2): 317-30, 2016 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27058664
2.
European Groundshot-addressing Europe's cancer research challenges: a Lancet Oncology Commission.
Lancet Oncol
; 24(1): e11-e56, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36400101
3.
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.
Nature
; 552(7683): 116-120, 2017 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29186113
4.
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein.
Molecules
; 27(23)2022 Dec 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36500607
5.
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.
Nature
; 508(7494): 118-22, 2014 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24670642
6.
Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma.
Int J Mol Sci
; 21(12)2020 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32599901
7.
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer.
Gut
; 67(11): 1995-2005, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28982739
8.
Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor.
Int J Cancer
; 143(4): 907-920, 2018 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29542109
9.
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
Nature
; 483(7387): 100-3, 2012 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22281684
10.
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Nature
; 486(7404): 532-6, 2012 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-22722830
11.
Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer.
Br J Cancer
; 117(3): 347-352, 2017 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28654634
12.
Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
FASEB J
; 29(2): 464-76, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25359494
13.
Targeting oncogenic serine/threonine-protein kinase BRAF in cancer cells inhibits angiogenesis and abrogates hypoxia.
Proc Natl Acad Sci U S A
; 109(6): E353-9, 2012 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22203991
14.
Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.
Hum Mutat
; 35(2): 208-14, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24282149
15.
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer.
Genome Med
; 16(1): 15, 2024 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38243308
16.
Preclinical efficacy of carfilzomib in BRAF-mutant colorectal cancer models.
Mol Oncol
; 2024 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38348572
17.
Transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer.
Mol Oncol
; 2024 Mar 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38468448
18.
Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells.
Cell Rep Med
; 5(2): 101376, 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38228147
19.
Modeling tumor progression by the sequential introduction of genetic alterations into the genome of human normal cells.
Hum Mutat
; 34(2): 330-7, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23292961
20.
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Int J Cancer
; 133(5): 1259-65, 2013 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23404247