Detalhe da pesquisa
1.
Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism.
J Neurosci
; 35(19): 7332-48, 2015 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25972164
2.
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation.
J Biol Chem
; 290(3): 1319-31, 2015 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25416782
3.
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced by Ischemic Preconditioning.
Stroke
; 47(4): 1085-93, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26979866
4.
A new cell-penetrating peptide that blocks the autoinhibitory XIP domain of NCX1 and enhances antiporter activity.
Mol Ther
; 23(3): 465-76, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25582710
5.
NCX3 regulates mitochondrial Ca(2+) handling through the AKAP121-anchored signaling complex and prevents hypoxia-induced neuronal death.
J Cell Sci
; 126(Pt 24): 5566-77, 2013 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24101730
6.
Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells.
J Neurosci Res
; 93(1): 167-77, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25093670
7.
MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter.
J Pharmacol Exp Ther
; 352(2): 236-43, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25467131
8.
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death.
Toxicol Appl Pharmacol
; 288(3): 387-98, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26307266
9.
MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits.
Mol Ther
; 22(10): 1829-38, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24954474
10.
Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di(2-ethylhexyl)phthalate (DEHP), determining neuronal death.
Toxicol Appl Pharmacol
; 280(1): 190-8, 2014 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25068794
11.
A new concept: Aß1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death.
J Neurosci
; 32(31): 10609-17, 2012 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22855810
12.
Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage.
Mol Pharmacol
; 83(1): 142-56, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23066092
13.
nNOS and p-ERK involvement in the neuroprotection exerted by remote postconditioning in rats subjected to transient middle cerebral artery occlusion.
Neurobiol Dis
; 54: 105-14, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23454199
14.
NCX1 is a new rest target gene: role in cerebral ischemia.
Neurobiol Dis
; 50: 76-85, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23069678
15.
NCX as a key player in the neuroprotection exerted by ischemic preconditioning and postconditioning.
Adv Exp Med Biol
; 961: 223-40, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23224883
16.
New roles of NCX in glial cells: activation of microglia in ischemia and differentiation of oligodendrocytes.
Adv Exp Med Biol
; 961: 307-16, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23224890
17.
Transcriptional regulation of ncx1 gene in the brain.
Adv Exp Med Biol
; 961: 137-45, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23224876
18.
New insights in mitochondrial calcium handling by sodium/calcium exchanger.
Adv Exp Med Biol
; 961: 203-9, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23224881
19.
Genetically modified mice as a strategy to unravel the role played by the Na(+)/Ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits.
Adv Exp Med Biol
; 961: 213-22, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23224882
20.
Na+ -Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory.
J Neurosci
; 31(20): 7312-21, 2011 May 18.
Artigo
Inglês
| MEDLINE | ID: mdl-21593315