Detalhe da pesquisa
1.
Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.
J Neurochem
; 161(6): 463-477, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35536742
2.
Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.
Proc Natl Acad Sci U S A
; 115(30): E7023-E7032, 2018 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29987039
3.
Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal Neurons.
Front Mol Neurosci
; 15: 945348, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35845610
4.
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.
J Pharmacol Exp Ther
; 339(1): 115-24, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21775475
5.
Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps.
BMC Physiol
; 11: 1, 2011 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-21211044
6.
The 24-hour respiratory quotient predicts energy intake and changes in body mass.
Am J Physiol Regul Integr Comp Physiol
; 298(3): R747-54, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20018821
7.
Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.
J Pharmacol Exp Ther
; 329(3): 1178-86, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19252061
8.
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.
Mol Cell Biol
; 26(1): 28-38, 2006 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-16354677
9.
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice.
Regul Pept
; 150(1-3): 55-61, 2008 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-18453014
10.
Ageing and metabolism: drug discovery opportunities.
Nat Rev Drug Discov
; 4(7): 569-80, 2005 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15976816
11.
Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.
Aging Cell
; 5(2): 119-26, 2006 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-16626391
12.
Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan.
Curr Alzheimer Res
; 4(2): 153-7, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17430240
13.
Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2.
J Neurosci
; 23(20): 7577-85, 2003 Aug 20.
Artigo
Inglês
| MEDLINE | ID: mdl-12930796
14.
Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.
J Med Chem
; 48(25): 8045-54, 2005 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16335928
15.
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.
FEBS Lett
; 530(1-3): 73-8, 2002 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-12387869
16.
A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels.
J Biomol Screen
; 7(1): 79-85, 2002 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-11897058
17.
SIRT1-independent mechanisms of the putative sirtuin enzyme activators SRT1720 and SRT2183.
Future Med Chem
; 2(12): 1751-9, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21428798
18.
Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency.
Growth Horm IGF Res
; 20(1): 73-9, 2010 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19747867
19.
Translating the human microbiome.
Nat Biotechnol
; 31(4): 304-8, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23563424
20.
Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase.
Cytometry A
; 69(11): 1123-31, 2006 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17051583