Detalhe da pesquisa
1.
In-depth analysis of data from the RAS-ALS study reveals new insights in rasagiline treatment for amyotrophic lateral sclerosis.
Eur J Neurol
; 31(4): e16204, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38240416
2.
Loss of hypothalamic MCH decreases food intake in amyotrophic lateral sclerosis.
Acta Neuropathol
; 145(6): 773-791, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37058170
3.
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.
Neurobiol Dis
; 152: 105289, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33577922
4.
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
EMBO J
; 35(10): 1077-97, 2016 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26951610
5.
Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis.
Ann Neurol
; 82(3): 444-456, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28856708
6.
Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration.
Hum Mol Genet
; 24(8): 2228-40, 2015 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25552654
7.
Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Acta Neuropathol
; 133(6): 887-906, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28243725
8.
Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosis.
Brain
; 139(Pt 4): 1106-22, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26984187
9.
Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.
Acta Neuropathol
; 131(3): 465-80, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26744351
10.
Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency.
Sci Transl Med
; 16(738): eadg3665, 2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38478631
11.
Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes.
Prog Neurobiol
; 227: 102483, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37327984
12.
Integrative genetic analysis illuminates ALS heritability and identifies risk genes.
Nat Commun
; 14(1): 342, 2023 01 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36670122
13.
Evaluation of a 5-HT2B receptor agonist in a murine model of amyotrophic lateral sclerosis.
Sci Rep
; 11(1): 23582, 2021 12 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34880312
14.
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation.
Mol Neurodegener
; 16(1): 61, 2021 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34488813
15.
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Nat Commun
; 12(1): 3028, 2021 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34021132
16.
FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis.
Nat Neurosci
; 22(11): 1793-1805, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31591561
17.
Author Correction: Integrative genetic analysis illuminates ALS heritability and identifies risk genes.
Nat Commun
; 14(1): 8026, 2023 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38049418