Detalhe da pesquisa
1.
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Mol Cell
; 83(7): 1093-1108.e8, 2023 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36863348
2.
Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase.
Mol Cell
; 72(2): 380-394.e7, 2018 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30293782
3.
Excessive apoptosis of Rip1-deficient T cells leads to premature aging.
EMBO Rep
; 24(12): e57925, 2023 Dec 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37965894
4.
Structural and functional insights into the epigenetic regulator MRG15.
Acta Pharmacol Sin
; 45(5): 879-889, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38191914
5.
MRG15 aggravates non-alcoholic steatohepatitis progression by regulating the mitochondrial proteolytic degradation of TUFM.
J Hepatol
; 77(6): 1491-1503, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35985547
6.
NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143.
Cell Commun Signal
; 20(1): 87, 2022 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35705994
7.
In Vivo AAV-CRISPR/Cas9-Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia.
Circulation
; 141(1): 67-79, 2020 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31779484
8.
Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells.
Pflugers Arch
; 473(7): 991-1007, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34031754
9.
microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle.
Proc Natl Acad Sci U S A
; 115(46): E10849-E10858, 2018 11 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30373812
10.
[Applications of stem cell disease models in liver metabolic research and drug development].
Sheng Li Xue Bao
; 73(5): 694-706, 2021 Oct 25.
Artigo
Chinês
| MEDLINE | ID: mdl-34708227
11.
Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats.
J Biol Chem
; 293(18): 6883-6892, 2018 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29507093
12.
CRISPR/Cas9 with single guide RNA expression driven by small tRNA promoters showed reduced editing efficiency compared to a U6 promoter.
RNA
; 23(1): 1-5, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27742910
13.
Porphyromonas gingivalis-derived lipopolysaccharide causes excessive hepatic lipid accumulation via activating NF-κB and JNK signaling pathways.
Oral Dis
; 25(7): 1789-1797, 2019 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-31283861
14.
CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo-Brief Report.
Arterioscler Thromb Vasc Biol
; 36(5): 783-6, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26941020
15.
Applications of genome editing tools in precision medicine research.
Yi Chuan
; 39(3): 177-188, 2017 03 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28420614
16.
Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.
Circ Res
; 115(5): 488-92, 2014 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24916110
17.
Correction: Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats.
J Biol Chem
; 294(21): 8348, 2019 May 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31127060
18.
Spotlight on gene therapy in China.
Gene Ther
; 27(7-8): 307-308, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32728206
19.
[Efficient genome editing in human pluripotent stem cells through CRISPR/Cas9].
Yi Chuan
; 37(11): 1167-73, 2015 11.
Artigo
Chinês
| MEDLINE | ID: mdl-26582531
20.
Use of genome editing tools in human stem cell-based disease modeling and precision medicine.
Yi Chuan
; 37(10): 983-91, 2015 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26496750