Detalhe da pesquisa
1.
Alternative lung cell model systems for toxicology testing strategies: Current knowledge and future outlook.
Semin Cell Dev Biol
; 147: 70-82, 2023 09 30.
Artigo
Inglês
| MEDLINE | ID: mdl-36599788
2.
Multi-endpoint analysis of cadmium chloride-induced genotoxicity shows role for reactive oxygen species and p53 activation in DNA damage induction, cell cycle irregularities, and cell size aberrations.
Mutagenesis
; 39(1): 13-23, 2024 Feb 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37555614
3.
Adapting the in vitro micronucleus assay (OECD Test Guideline No. 487) for testing of manufactured nanomaterials: recommendations for best practices.
Mutagenesis
; 39(3): 205-217, 2024 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38502821
4.
An integrated in vitro carcinogenicity test that distinguishes between genotoxic carcinogens, non-genotoxic carcinogens, and non-carcinogens.
Mutagenesis
; 39(2): 69-77, 2024 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38301659
5.
Determining the toxicological effects of indoor air pollution on both a healthy and an inflammatory-comprised model of the alveolar epithelial barrier in vitro.
Part Fibre Toxicol
; 21(1): 25, 2024 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38760786
6.
Current status and future challenges of genotoxicity OECD Test Guidelines for nanomaterials: a workshop report.
Mutagenesis
; 38(4): 183-191, 2023 08 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37234002
7.
Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer.
Cell Mol Biol (Noisy-le-grand)
; 69(4): 179-187, 2023 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-37329528
8.
The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability-A PATROLS Perspective on New Approach Methodologies.
Small
; 18(17): e2200231, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35324067
9.
A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective.
Part Fibre Toxicol
; 19(1): 59, 2022 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36104711
10.
In Vitro Primary-Indirect Genotoxicity in Bronchial Epithelial Cells Promoted by Industrially Relevant Few-Layer Graphene.
Small
; 17(15): e2002551, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32734718
11.
In Vitro Three-Dimensional Liver Models for Nanomaterial DNA Damage Assessment.
Small
; 17(15): e2006055, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33448117
12.
Simulating Nanomaterial Transformation in Cascaded Biological Compartments to Enhance the Physiological Relevance of In Vitro Dosing Regimes: Optional or Required?
Small
; 17(15): e2004630, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33475244
13.
In vitro and integrated in vivo strategies to reduce animal use in genotoxicity testing.
Mutagenesis
; 36(6): 389-400, 2021 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-34555171
14.
Few-layer graphene induces both primary and secondary genotoxicity in epithelial barrier models in vitro.
J Nanobiotechnology
; 19(1): 24, 2021 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33468168
15.
Understanding the impact of more realistic low-dose, prolonged engineered nanomaterial exposure on genotoxicity using 3D models of the human liver.
J Nanobiotechnology
; 19(1): 193, 2021 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34183029
16.
Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action.
Arch Toxicol
; 95(1): 321-336, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32910239
17.
An Alternative Perspective towards Reducing the Risk of Engineered Nanomaterials to Human Health.
Small
; 16(36): e2002002, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32755066
18.
Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety.
Chem Res Toxicol
; 33(5): 1061-1073, 2020 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32307980
19.
Detection of urethane-induced genotoxicity in vitro using metabolically competent human 2D and 3D spheroid culture models.
Mutagenesis
; 35(6): 445-452, 2020 12 31.
Artigo
Inglês
| MEDLINE | ID: mdl-33219664
20.
Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations.
Mutagenesis
; 35(4): 319-330, 2020 09 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32780103