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Int J Mol Sci ; 25(11)2024 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-38891938

RESUMO

Neurological disorders present a wide range of symptoms and challenges in diagnosis and treatment. Cannabis sativa, with its diverse chemical composition, offers potential therapeutic benefits due to its anticonvulsive, analgesic, anti-inflammatory, and neuroprotective properties. Beyond cannabinoids, cannabis contains terpenes and polyphenols, which synergistically enhance its pharmacological effects. Various administration routes, including vaporization, oral ingestion, sublingual, and rectal, provide flexibility in treatment delivery. This review shows the therapeutic efficacy of cannabis in managing neurological disorders such as epilepsy, neurodegenerative diseases, neurodevelopmental disorders, psychiatric disorders, and painful pathologies. Drawing from surveys, patient studies, and clinical trials, it highlights the potential of cannabis in alleviating symptoms, slowing disease progression, and improving overall quality of life for patients. Understanding the diverse therapeutic mechanisms of cannabis can open up possibilities for using this plant for individual patient needs.


Assuntos
Cannabis , Epilepsia , Doenças Neurodegenerativas , Humanos , Cannabis/química , Doenças Neurodegenerativas/tratamento farmacológico , Epilepsia/tratamento farmacológico , Transtornos Mentais/tratamento farmacológico , Animais , Dor/tratamento farmacológico , Anticonvulsivantes/uso terapêutico , Canabinoides/uso terapêutico , Canabinoides/farmacologia , Extratos Vegetais/uso terapêutico , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Fármacos Neuroprotetores/uso terapêutico , Fármacos Neuroprotetores/farmacologia , Fármacos Neuroprotetores/química , Analgésicos/uso terapêutico , Analgésicos/química , Analgésicos/farmacologia
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