Detalhe da pesquisa
1.
Segregation, immunohistochemical, molecular and functional analyses classify a novel missense variant in fumarate hydratase (FH) as pathogenic.
Genes Chromosomes Cancer
; 63(2): e23221, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38682608
2.
Oncology clinic-based germline genetic testing for exocrine pancreatic cancer enables timely return of results and unveils low uptake of cascade testing.
J Med Genet
; 59(8): 793-800, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34556502
3.
Is Biannual Surveillance for Pancreatic Cancer Sufficient in Individuals With Genetic Syndromes or Familial Pancreatic Cancer?
J Natl Compr Canc Netw
; 20(6): 663-673.e12, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35714671
4.
A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.
PLoS Genet
; 15(8): e1008344, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31469826
5.
Long-term tumour dormancy in a BRCA1 heterozygote.
J Med Genet
; 60(1): 33-35, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35039446
6.
Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry.
J Proteome Res
; 12(1): 272-81, 2013 Jan 04.
Artigo
Inglês
| MEDLINE | ID: mdl-23157168
7.
Unusual Aspects of Small Cell Carcinoma of the Ovary of Hypercalcaemic Type: Retained SMARCA4 Immunohistochemical Staining and Positive Staining With TLE1.
Am J Surg Pathol
; 47(11): 1261-1266, 2023 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37345679
8.
Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation.
J Biol Chem
; 286(35): 30898-30910, 2011 Sep 02.
Artigo
Inglês
| MEDLINE | ID: mdl-21730074
9.
Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma.
Front Oncol
; 12: 860767, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35547873
10.
Conformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase.
Biochim Biophys Acta
; 1799(8): 575-87, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20478425
11.
Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II.
Protein Expr Purif
; 69(1): 83-90, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19567268
12.
A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer.
Clin Cancer Res
; 26(20): 5462-5476, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32816949
13.
Use of site-specific protein-DNA photocrosslinking of purified complexes to analyze the topology of the RNA polymerase II transcription initiation complex.
Methods Mol Biol
; 543: 439-51, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19378180
14.
Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.
BMC Biophys
; 5: 11, 2012 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22676913