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1.
Methods Mol Biol ; 2147: 31-42, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-32840808

RESUMO

Scaffolds are often used in bioengineering to replace damaged tissues. They promote cell ingrowth and provide mechanical support until cells regenerate. Such scaffolds are often made using the additive manufacturing process, given its ability to create complex shapes, affordability, and the potential for patient-specific solutions. The success of the implant is closely related to the match of the scaffold mechanical properties to those of the host tissue. Many biological tissues show properties that vary in space. Therefore, the aim is to manufacture materials with variable properties, commonly referred to as functionally graded materials. Here we present a novel technique used to manufacture porous films with functionally graded properties using 3D printers. Such an approach exploits the control of a process parameter, without any hardware modification. The mechanical properties of the manufactured films have been experimentally tested and analytically characterized.


Assuntos
Membranas Artificiais , Impressão Tridimensional , Linguagens de Programação , Engenharia Tecidual/instrumentação , Alicerces Teciduais/química , Desenho Assistido por Computador/instrumentação , Humanos , Manufaturas , Fenômenos Mecânicos , Impressão Tridimensional/instrumentação , Próteses e Implantes , Propriedades de Superfície , Engenharia Tecidual/métodos
2.
Phys Rev E ; 97(6-1): 063102, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30011509

RESUMO

This study provides sufficient conditions for the temporal monotonic decay of enstrophy for two-dimensional perturbations traveling in the incompressible, viscous, plane Poiseuille, and Couette flows. Extension of Synge's procedure [J. L. Synge, Proc. Fifth Int. Congress Appl. Mech. 2, 326 (1938); Semicentenn. Publ. Am. Math. Soc. 2, 227 (1938)] to the initial-value problem allow us to find the region of the wave-number-Reynolds-number map where the enstrophy of any initial disturbance cannot grow. This region is wider than that of the kinetic energy. We also show that the parameter space is split into two regions with clearly distinct propagation and dispersion properties.

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