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1.
Public Health Nutr ; 23(17): 3104-3113, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32799964

RESUMO

OBJECTIVE: To determine if a global mid-upper arm circumference (MUAC) cut-off can be established to classify underweight in adults (men and non-pregnant women). DESIGN: We conducted an individual participant data meta-analysis (IPDMA) to explore the sensitivity (SENS) and specificity (SPEC) of various MUAC cut-offs for identifying underweight among adults (defined as BMI < 18·5 kg/m2). Measures of diagnostic accuracy were determined every 0·5 cm across MUAC values from 19·0 to 26·5 cm. A bivariate random effects model was used to jointly estimate SENS and SPEC while accounting for heterogeneity between studies. Various subgroup analyses were performed. SETTING: Twenty datasets from Africa, South Asia, Southeast Asia, North America and South America were included. PARTICIPANTS: All eligible participants from the original datasets were included. RESULTS: The total sample size was 13 835. Mean age was 32·6 years and 65 % of participants were female. Mean MUAC was 25·7 cm, and 28 % of all participants had low BMI (<18·5 kg/m2). The area under the receiver operating characteristic curve for the pooled dataset was 0·91 (range across studies 0·61-0·98). Results showed that MUAC cut-offs in the range of ≤23·5 to ≤25·0 cm could serve as an appropriate screening indicator for underweight. CONCLUSIONS: MUAC is highly discriminatory in its ability to distinguish adults with BMI above and below 18·5 kg/m2. This IPDMA is the first step towards determining a global MUAC cut-off for adults. Validation studies are needed to determine whether the proposed MUAC cut-off of 24 cm is associated with poor functional outcomes.


Assuntos
Braço , Magreza , Adulto , África , Antropometria , Braço/anatomia & histologia , Ásia , Índice de Massa Corporal , Estudos Transversais , Feminino , Humanos , Masculino , América do Norte , América do Sul
2.
J Urban Health ; 95(4): 564-575, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-30030685

RESUMO

When individuals are on probation, they face challenges with securing employment and safe housing due to their criminal records, which may make food access problematic. Food insecurity is a construct used as a marker for food access that considers financial constraints and has been associated with poorer health and substance use. There is limited research on the extent of food insecurity and associated morbidities and substance use among adults on probation. We conducted a cross-sectional study in 2016, surveying 304 probationers in Rhode Island to determine whether food insecurity is associated with obesity, high blood pressure, depression, and substance use. Separate logistic regression models were used to determine the associations between food insecurity and obesity, high blood pressure, depression, and substance use. Food insecurity was experienced by 70% of our study population. The estimated prevalence of high blood pressure was significantly higher in our study sample compared to the general US population. Food insecurity was not associated with obesity, high blood pressure, or current drug use in this study sample. Food insecurity was independently associated with more than three times greater odds of being depressed (AOR 3.33, 95%CI 1.89, 5.86) and a nearly twofold greater odds of self-reporting a lower health status (AOR 1.91, 95%CI 1.18, 3.10) after adjusting for gender, race/ethnicity, age, income categories, and being homeless. Probationers were found to have a higher estimated prevalence of high blood pressure and food insecurity compared to the general population, which highlights the health disparities faced by this population. Our findings have important implications for future research and interventions to decrease the health burden not only on the individuals but their families and communities.


Assuntos
Abastecimento de Alimentos/estatística & dados numéricos , Nível de Saúde , Pessoas Mal Alojadas/estatística & dados numéricos , Morbidade , Prisioneiros/estatística & dados numéricos , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Prevalência , Rhode Island/epidemiologia , Inquéritos e Questionários , Adulto Jovem
3.
BMC Public Health ; 18(1): 289, 2018 02 27.
Artigo em Inglês | MEDLINE | ID: mdl-29482529

RESUMO

BACKGROUND: Individuals on probation experience economic disadvantage because their criminal records often prohibit gainful employment, which compromises their ability to access the basic components of wellbeing. Unemployment and underemployment have been studied as distinct phenomenon but no research has examined multiple determinants of health in aggregate or explored how these individuals prioritize each of these factors. This study identified and ranked competing priorities in adults on probation and qualitatively explored how these priorities impact health. METHODS: We conducted in-depth interviews in 2016 with 22 adults on probation in Rhode Island to determine priority rankings of basic needs. We used Maslow's hierarchy of needs theory and the literature to guide the priorities we pre-selected for probationers to rank. Within a thematic analysis framework, we used a modified ranking approach to identify the priorities chosen by participants and explored themes related to the top four ranked priorities. RESULTS: We found that probationers ranked substance use recovery, employment, housing, and food intake as the top four priorities. Probationers in recovery reported sobriety as the most important issue, a necessary basis to be able to address other aspects of life. Participants also articulated the interrelatedness of difficulties in securing employment, food, and housing; these represent stressors for themselves and their families, which negatively impact health. Participants ranked healthcare last and many reported underinsurance as an issue to accessing care. CONCLUSIONS: Adults on probation are often faced with limited economic potential and support systems that consistently place them in high-risk environments with increased risk for recidivism. These findings emphasize the need for policies that address the barriers to securing gainful employment and safe housing. Interventions that reflect probationer priorities are necessary to begin to mitigate the health disparities in this population.


Assuntos
Criminosos/psicologia , Emprego , Abastecimento de Alimentos , Habitação , Estresse Psicológico/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/reabilitação , Adulto , Criminosos/estatística & dados numéricos , Feminino , Disparidades nos Níveis de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Pesquisa Qualitativa , Rhode Island/epidemiologia
4.
J Fam Pract ; 72(7): 286-291, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37729141

RESUMO

The evidence supports patient use of this simple equation to evaluate the nutrition labels of packaged carbohydrate foods in the grocery aisle in order to make healthier decisions.


Assuntos
Carga Glicêmica , Humanos , Diretivas Antecipadas , Nível de Saúde
5.
Front Public Health ; 11: 1212141, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37732089

RESUMO

Objective: To qualitatively explore the impact of anti-Asian racism in a Chinese community in the greater Boston area. Methods: Individual semi-structured interviews (n = 27) were conducted between June and September 2021. Eligible participants were ethnic Chinese immigrants living in the Boston area, who were recruited through a community-based organization and by word-of-mouth. Interviews were conducted in Mandarin and Cantonese and translated into English. Data were coded and analyzed using a directed approach to content analysis. Results: The majority of participants reported personal experiences of anti-Asian racism, ranging from microaggressions to violent attacks. Although lockdown and isolation during COVID-19 affected all communities, the Chinese community suffered unique and prolonged trauma stemming from the fear of violent attacks against Asians. The older person/people, in particular, were severely isolated due to fear of exposure to anti-Asian hate crimes. Participants reported a variety of emotional, mental, and physical health effects associated with feelings of fear, anxiety, isolation, and powerlessness. Many preferred to engage in self-protective behavior changes rather than relying on external resources. Conclusion: Participants advocated for more education, community, and governmental support, and increased allyship between communities of color. These findings provide cultural context on the trauma this population faces and can inform further actions to address the wide range of reported health effects.


Assuntos
COVID-19 , Racismo , Humanos , Idoso , Boston , Controle de Doenças Transmissíveis , Poder Psicológico
6.
Curr Nutr Rep ; 11(3): 407-415, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-35606619

RESUMO

PURPOSE OF REVIEW: The purpose of this paper is to provide an overview of the state of the science of food and nutrition security among justice-impacted populations, identify who might be most at-risk and health consequences, and to highlight areas for continued research and policy implications. RECENT FINDINGS: This population is at-risk for experiencing food and nutrition insecurity due to high rates of unemployment, parental history of incarceration, housing instability, depressive symptoms, and social isolation, which result from involvement with the corrections system. Health consequences associated with food insecurity include depressive symptoms, self-reporting lower health status, and engaging in HIV-risk behaviors. The justice-impacted population has a disproportionately higher risk of chronic and infectious diseases compared to the general population. Compounding this with food and nutrition insecurity can exacerbate these outcomes and further contribute to poor health. Structural issues related to nutrition safety net programs and employment create barriers to healthy food access. More research related to food, employment, and corrections system policies are critical to improve the well-being of this population.


Assuntos
Abastecimento de Alimentos , Justiça Social , Insegurança Alimentar , Nível de Saúde , Humanos , Estado Nutricional
7.
J Correct Health Care ; 28(4): 274-282, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35687477

RESUMO

This cross-sectional study examined whether the probation office setting was feasible to screen adults on probation for cardiometabolic risk factors, measure risk profiles, and estimate the prevalence of obesity, hypertension, hypercholesterolemia, and diabetes. During June and August 2019, screening included blood pressure, anthropometrics, total and high-density lipoprotein (HDL) cholesterol, and glucose. A survey included demographics, medical history, and current medication. The participation rate was 36% (N = 202). The screening identified 5% had hypercholesterolemia, 38% of men and 50% of women had low HDL cholesterol, 70% had overweight/obesity, 31% of men and 55% of women had elevated waist circumferences, and 26.7% had Stage 1 hypertension. Of individuals with a history of hypertension (n = 74), 77% had elevated blood pressure. Of those with a history of diabetes (n = 27), 22% had hyperglycemia, independent of whether they reported being prescribed medication. The screening identified 11% with Stage 2 hypertension, 27% with Stage 1 hypertension, 22% with elevated blood pressure, and 5% with hyperglycemia. Our findings suggest it is feasible to identify individuals at high risk for cardiometabolic disorders during routine probation office visits. These data can then be used to provide referrals for treatment to improve long-term health outcomes.


Assuntos
Doenças Cardiovasculares , Diabetes Mellitus , Hipercolesterolemia , Hiperglicemia , Hipertensão , Adulto , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/prevenção & controle , HDL-Colesterol/uso terapêutico , Estudos Transversais , Estudos de Viabilidade , Feminino , Humanos , Hipercolesterolemia/epidemiologia , Hipertensão/epidemiologia , Masculino , Obesidade/epidemiologia , Prevalência , Fatores de Risco , Circunferência da Cintura
8.
J Nutr Educ Behav ; 54(6): 510-520, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35618404

RESUMO

OBJECTIVE: To examine food access, dietary intake, and perceptions about diet and associations with health among adults on probation. DESIGN: Using a mixed-methods approach, interviews were used to understand food access, dietary intake, and diet and associations with health. A survey measured self-assessed diet quality and diet and associations with health. SETTING: One probation office in Rhode Island. PARTICIPANTS: English-speaking adults on probation in 2016 (n = 22 interviews, n = 304 surveys). MAIN OUTCOME MEASURE(S): Food access, dietary intake, knowledge about diet and health, and perceptions about healthy food. ANALYSIS: We used a thematic analytic approach to analyze the interviews. Descriptive statistics were performed for the survey. RESULTS: Many interviewees had inadequate food access, although most participated in the Supplemental Nutrition Assistance Program, and some received food from food banks. Interviewees primarily shopped at grocery stores and prepared food at home, and dietary intakes did not meet the 2020-2025 Dietary Guidelines for Americans. Almost two-thirds (64.2%) of survey participants reported good or fair diet quality. Based on the survey results, the majority of participants strongly agreed and agreed with the statements, "The types of foods I eat affect my health" and "The types of food I eat affect my weight." CONCLUSIONS AND IMPLICATIONS: This study identified low-quality dietary intake and food acquisition strategies, such as shopping sales, buying bulk, and going to multiple stores, by US adults on probation to access food with limited resources. Participants reported interest in eating healthier foods and knew there was a connection between dietary intake and health. These data support addressing ways to improve food access and dietary quality, focusing on future programs and policies for this population.


Assuntos
Assistência Alimentar , Alimentos , Adulto , Dieta , Ingestão de Alimentos , Abastecimento de Alimentos , Humanos , Estados Unidos
9.
J Health Care Poor Underserved ; 32(2): 654-663, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34120966

RESUMO

Millions of Americans are formerly or currently under correctional supervision and their involvement with the correctional system imposes collateral consequences beyond sentencing times. We explore the creation of extended punishment through the intersection of correctional system involvement, food insecurity, and two Supplemental Nutrition Assistance Program (SNAP) policies. Given the high prevalence of food insecurity, individuals with correctional supervision involvement are likely to need assistance from SNAP; however, they face more barriers accessing SNAP benefits than the general population. We highlight two policies in particular: the restrictions for individuals with drug felony convictions and the able-bodied adults without dependents work requirement. Due to challenges with securing gainful employment and the need for SNAP benefits, these two policies create disparities with participation in the program and increase risk for food insecurity and other poor health outcomes among this population.


Assuntos
Assistência Alimentar , Adulto , Emprego , Insegurança Alimentar , Abastecimento de Alimentos , Humanos , Pobreza , Prevalência , Estados Unidos
10.
AIDS Patient Care STDS ; 35(9): 360-369, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34463134

RESUMO

Time spent in jail can provide opportunities to deliver comprehensive medical care, including screening and treatment for HIV; however, engagement in HIV care postrelease is often fragmented. Identifying ways to improve the transition of care from jail to community for people with HIV (PWH) may help with engagement in HIV care postrelease. We evaluated the current HIV care transition processes of one jail in Massachusetts and identified change ideas to facilitate improving the transition of care from the jail to the community for PWH. We conducted qualitative interviews in 2018-2019 with incarcerated men with HIV (n = 17), jail staff (n = 7), and community providers (n = 6) to understand the processes of HIV care prerelease from the jail and engagement in care on release. Data from these interviews and quality improvement tools were used to identify ways to improve the release process for PWH, such as using a release planning checklist, to help ensure that a 30-day supply of HIV medication and an appointment with a community provider within 30 days of release were provided. We identified communication process inefficiencies related to knowing release dates between the HIV care team and case managers that prevented providing HIV medications on release. We worked with jail administrators to find ways to improve the prerelease planning process, which is vital to the continuity of successful HIV care. The use of quality improvement methods generated a list of testable change ideas to improve the release planning process to better align with the Centers for Disease Control and Prevention guidelines, which has implications for PWH and public health.


Assuntos
Infecções por HIV , Prisioneiros , Agendamento de Consultas , Infecções por HIV/tratamento farmacológico , Humanos , Prisões Locais , Masculino , Transferência de Pacientes , Prisões , Saúde Pública
11.
World Med Health Policy ; 12(4): 357-373, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33362941

RESUMO

Bipartisan governmental representatives and the public support investment in health care, housing, education, and nutrition programs, plus resources for people leaving prison and jail (Halpin, 2018; Johnson & Beletsky, 2020; USCCR, 2019). The Personal Responsibility and Work Opportunity Reconciliation Act of 1996 banned people with felony drug convictions from receiving food stamps or Supplemental Nutrition Assistance Program (SNAP) benefits. Food insecurity, recidivism, and poor mental and physical health outcomes are associated with such bans. Several states have overturned SNAP benefit bans, yet individuals with criminal convictions are still denied benefits due to eligibility criteria modifications. COVID-19 has impaired lower-income, food-insecure communities, which disproportionately absorb people released from prison and jail. Reentry support is sorely lacking. Meanwhile, COVID-19 introduces immediate novel health risks, economic insecurity, and jail and prison population reductions and early release. Thirty to 50 percent of people in prisons and jails, which are COVID-19 hotspots, have been released early (Flagg & Neff, 2020; New York Times, 2020; Vera, 2020). The Families First Coronavirus Response Act increases flexibility in providing emergency SNAP supplements and easing program administration during the pandemic. Meanwhile, the U.S. Commission on Civil Rights recommends eliminating SNAP benefit restrictions based on criminal convictions, which fail to prevent recidivism, promote public safety, or relate to underlying crimes. Policy improvements, administrative flexibility, and cross-sector collaboration can facilitate SNAP benefit access, plus safer, healthier transitioning from jail or prison to the community.

12.
Am J Health Promot ; 34(6): 659-663, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32048857

RESUMO

PURPOSE: To determine the feasibility of applying a medical wellness group (WG) model to a community setting to improve cardiometabolic health. DESIGN: This quasi-experiment was designed to compare individuals participating in the WG to participants in the control group who received general lectures on nutrition, physical activity, and sleep. SETTING: A suburb north of Boston, Massachusetts. PARTICIPANTS: Forty-five adults were in the WG and 10 in the control group. INTERVENTION: Fourteen weekly 90-minute sessions, led by a physician and dietitian, focusing on nutrition, physical activity, and sleep, compared to controls receiving two 30-minute general wellness lectures provided within 3 months. MEASURES: Pre- and postweight, waist circumference, hemoglobin A1C (HbA1c), and serum lipids; a survey measuring beliefs, attitudes, and intentions related to behavioral change. ANALYSIS: T tests examined the mean change in biometric measurements. The Wilcoxon test was used to compare the ordinal questions in baseline and final survey results. The Mann-Whitney test was used to compare final survey results between groups. RESULTS: The WG demonstrated desirable difference-in-difference between groups in weight (P < .001), waist circumference (P < .001), and total cholesterol (P = .03) compared to the control group. Mean change of HbA1c and triglycerides was not different between groups. Survey results showed that attitudes, perceived behavioral control, and feeling supported about wellness behaviors significantly improved from baseline to final visit in the WG (P = .002; P = .019, P = .006, respectively), but not among controls. CONCLUSION: Wellness groups are feasible and provide high levels of support and accountability that empower people to make behavioral changes to improve health.


Assuntos
Laboratórios , Redução de Peso , Adulto , Boston , Serviços de Saúde Comunitária , Hemoglobinas Glicadas/análise , Humanos , Massachusetts
13.
PLoS One ; 13(6): e0198598, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29883491

RESUMO

BACKGROUND: Individuals under community corrections supervision may be at increased risk for food insecurity because they face challenges similar to other marginalized populations, such as people experiencing housing instability or substance users. The prevalence of food insecurity and its correlates have not been studied in the community corrections population. METHODS: We conducted a cross-sectional study in 2016, surveying 304 probationers in Rhode Island to estimate the prevalence of food insecurity, identify food acquisition methods, and determine characteristics of groups most at-risk for food insecurity. We used chi-square and Fisher's exact tests to assess differences in sociodemographics and eating and food acquisition patterns, GIS to examine geospatial differences, and ordinal logistic regression to identify independent correlates across the four levels of food security. RESULTS: Nearly three-quarters (70.4%) of the participants experienced food insecurity, with almost half (48.0%) having very low food security. This is substantially higher than the general population within the state of Rhode Island, which reported a prevalence of 12.8% food insecurity with 6.1% very low food security in 2016. Participants with very low food security most often acquired lunch foods from convenience stores (and less likely from grocery stores) compared to the other three levels of food security. Participants did not differ significantly with regards to places for food acquisition related to breakfast or dinner meals based upon food security status. In adjusted models, being homeless (AOR 2.34, 95% CI: 1.31, 4.18) and depressed (AOR 3.12, 95% CI: 1.98, 4.91) were independently associated with a greater odds of being in a food insecure group. Compared to having help with meals none of the time, participants who reported having meal help all of the time (AOR 0.28, 95% CI: 0.12, 0.64), most of the time (AOR 0.31, 95% CI: 0.15, 0.61), and some of the time (AOR 0.54, 95% CI: 0.29, 0.98) had a lower odds of being in a food insecure group. Food insecure participants resided in different neighborhoods than food secure participants. The highest density of food insecure participants resided in census tracts with the lowest median incomes for the general population. The areas of highest density for each level of food security for our participants were in the census tracts with the lowest levels of full-time employment for the general population. CONCLUSIONS: The prevalence of food insecurity and very low food security were markedly higher in our probation population compared to the general RI population. These findings suggest that access to food on a regular basis is a challenge for adults on probation. Depression and being homeless were independently associated with a greater odds of being in a food insecure group. In addition to intervening directly on food insecurity, developing interventions and policies that address the contributing factors of food insecurity, such as safe housing and treatment for depression, are critical.


Assuntos
Criminosos/psicologia , Depressão/psicologia , Ingestão de Alimentos/psicologia , Abastecimento de Alimentos/estatística & dados numéricos , Pessoas Mal Alojadas/psicologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Rhode Island , Fatores Socioeconômicos , Adulto Jovem
14.
J Am Diet Assoc ; 106(5): 728-32, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16647332

RESUMO

This study focused on dietary glycemic index because insulin resistance can be important in the pathogenesis of fat deposition in human immunodeficiency virus (HIV). We evaluated differences in past dietary glycemic intake between men with HIV who developed fat deposition and those who did not. This was a nested case-control study consisting of 37 cases and 37 controls from the Nutrition for Healthy Living cohort. Food records from 6 to 24 months prior to development of fat deposition in cases were analyzed and compared with controls. Cases were defined as men with a waist-to-hip ratio >0.95 and body mass index (calculated as kg/m(2)) between 23 and 26. Controls were matched by age, race, body mass index, highly active antiretroviral therapy use, and CD4 count. Food records were analyzed using t tests for normally distributed nutrients and Wilcoxon rank-sum tests for nutrients with skewed distributions. Glycemic index was calculated for each meal and day. There was no significant difference in glycemic index for meals and day between participants with or without fat deposition. Both groups had a moderate dietary glycemic index intake. This study showed no association between dietary glycemic index and development of fat deposition in HIV. Instead, results of this study depict the potential benefits associated with eating high-quality diets, primarily adequate fiber and protein intake. Diet can be important in preventing development of fat deposition in patients with HIV.


Assuntos
Composição Corporal , Dieta/normas , Índice Glicêmico , Soropositividade para HIV/complicações , Lipodistrofia , Adiposidade/fisiologia , Adulto , Terapia Antirretroviral de Alta Atividade , Índice de Massa Corporal , Contagem de Linfócito CD4 , Estudos de Casos e Controles , Registros de Dieta , Fibras na Dieta/administração & dosagem , Proteínas Alimentares/administração & dosagem , Humanos , Lipodistrofia/etiologia , Lipodistrofia/prevenção & controle , Masculino , Relação Cintura-Quadril
15.
Nutr Clin Care ; 8(1): 31-6, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15850232

RESUMO

HIV-associated body shape changes and metabolic abnormalities, called HIV-associated lipodystrophy, are being seen with increased frequency. These issues may be associated with an increased risk of other diseases, such as cardiovascular disease, or with poor adherence to antiretroviral medications. Diet may be useful in the prevention and treatment of lipodystrophy and is a cost-effective and non-toxic intervention. At present, there are limited data on nutrition and HIV-related body shape changes. The purpose of this article is to review the roles that diet may play in the development and treatment of fat deposition and fat atrophy.


Assuntos
Tecido Adiposo/metabolismo , Infecções por HIV/complicações , Síndrome de Lipodistrofia Associada ao HIV/dietoterapia , Dieta , Gorduras na Dieta/administração & dosagem , Fibras na Dieta/administração & dosagem , Humanos
16.
Am J Clin Nutr ; 78(4): 790-5, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14522738

RESUMO

BACKGROUND: Lipodystrophy has been described with increasing frequency in patients infected with HIV. This study focused on the identification of dietary components that may predispose HIV-positive patients to the development of fat deposition. OBJECTIVE: We evaluated differences in past dietary intake between men with HIV who developed fat deposition and those who did not. DESIGN: This nested case-control study consisted of 47 cases and 47 controls from the Nutrition for Healthy Living cohort. Food records from 6 to 24 mo before development of fat deposition in cases were analyzed and compared with food records from controls by using t tests for normally distributed nutrients and Wilcoxon rank-sum tests for nutrients with skewed distributions. RESULTS: HIV-positive patients without fat deposition had greater overall energy intakes (kcal/kg; P = 0.03) and greater intakes of total protein (P = 0.01), total dietary fiber (P = 0.01), soluble dietary fiber (P = 0.01), insoluble dietary fiber (P = 0.03), and pectin (P = 0.02) than did HIV-positive patients with fat deposition. Those without fat deposition also tended to currently perform more resistance training (P = 0.05) and to not be current smokers (P = 0.05). CONCLUSION: Our results indicate that an overall high-quality diet, rich in fiber and adequate in energy and protein, may be beneficial in preventing the development of fat deposition in persons infected with HIV. The results of this study further emphasize that a healthy lifestyle, including exercise and avoidance of unhealthy behaviors such as smoking, may also be similarly beneficial.


Assuntos
Fibras na Dieta/uso terapêutico , Soropositividade para HIV/complicações , Lipodistrofia , Lipodistrofia/etiologia , Adulto , Estudos de Casos e Controles , Dieta , Registros de Dieta , Humanos , Lipodistrofia/prevenção & controle , Masculino , Fatores de Risco
17.
Am J Clin Nutr ; 89(4): 1180-7, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19244367

RESUMO

BACKGROUND: HIV infection and its treatment are associated with abnormal lipid profiles. High triglyceride concentrations and low HDL-cholesterol concentrations are the most common health abnormalities and raise concerns about an increased risk of cardiovascular disease. OBJECTIVE: We compared the fatty acid patterns of serum phospholipids between persons with HIV and non-HIV controls to determine whether there are differences that explain the elevated triglyceride concentrations, insulin resistance, and inflammation that are part of the metabolic syndrome in patients with HIV. DESIGN: Thirty-nine persons with HIV and elevated serum triglycerides (>150 mg/dL) and/or indicators of insulin resistance were recruited to examine fatty acid profiles in serum phospholipid fractions relative to those of 2 control groups without HIV (n = 31). RESULTS: Higher concentrations of 16:1 and 18:0 fatty acids in the phospholipid fraction indicated increased lipogenesis in the HIV patients and in the non-HIV controls at risk of the metabolic syndrome. However, the subjects with HIV had higher concentrations of both n-6 (omega-6) and n-3 fatty acids of higher elongation and desaturation levels, which indicated a greater promotion of these pathways in this population. The nanomolar percentage (%nmol) arachidonic acid was the same in all 3 groups. CONCLUSIONS: Persons with and without HIV, at risk of the metabolic syndrome, show indications of increased lipogenesis, more so in subjects with HIV taking medication. Higher proportions of distal elongation and desaturation fatty acid products were seen only in the phospholipids fatty acid fraction of the subjects with HIV.


Assuntos
Fármacos Anti-HIV/efeitos adversos , Ácidos Graxos/sangue , Infecções por HIV/sangue , Hipertrigliceridemia/sangue , Síndrome Metabólica/sangue , Fosfolipídeos/química , Fármacos Anti-HIV/uso terapêutico , Estudos de Casos e Controles , Feminino , Infecções por HIV/complicações , Infecções por HIV/tratamento farmacológico , Humanos , Lipodistrofia/sangue , Lipodistrofia/induzido quimicamente , Lipodistrofia/complicações , Masculino , Pessoa de Meia-Idade , Triglicerídeos/sangue
18.
Am J Clin Nutr ; 90(6): 1566-78, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19846544

RESUMO

BACKGROUND: Elevated serum triglyceride and low HDL-cholesterol concentrations have been reported in persons with HIV. OBJECTIVE: The effect of a dietary intervention plus n-3 (omega-3) fatty acid supplementation on serum triglycerides and markers of insulin sensitivity was investigated. DESIGN: Fifty-four persons with HIV and elevated serum triglycerides (>150 mg/dL) and/or abnormal Quantitative Insulin Sensitivity Check Index values (<0.35 but >0.30) were recruited for a dietary intervention in which total fat, type of fat, fiber, and glycemic load were controlled along with supplementation with n-3 fatty acids to achieve an intake of 6 g/d. The subjects were randomly assigned to an intervention or control group, and serum lipids, markers of insulin sensitivity, and serum phospholipid fatty acids were measured in both groups at baseline, 3 wk, and 13 wk. RESULTS: Triglycerides in the intervention group decreased from a median of 180 mg/dL (interquartile range: 141, 396) to 114 mg/dL (interquartile range: 84, 169) from baseline to 3 wk, whereas they remained stable in the control group (P = 0.003). Serum phospholipid fatty acids indicated a decrease in de novo lipogenesis and a decrease in arachidonic acid (% nmol; P

Assuntos
Ácidos Graxos Ômega-3/administração & dosagem , Infecções por HIV/metabolismo , Triglicerídeos/sangue , Adulto , Ácido Araquidônico/sangue , Área Sob a Curva , Índice de Massa Corporal , HDL-Colesterol/sangue , Suplementos Nutricionais , Feminino , Humanos , Resistência à Insulina , Masculino , Pessoa de Meia-Idade , Fosfolipídeos/sangue
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