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Zhonghua Wai Ke Za Zhi ; (12): 260-264, 2023.
Artigo em Chinês | WPRIM | ID: wpr-970189

RESUMO

Gallbladder cancer(GBC)is one common type of bile tract cancers with poor prognosis. This review summarizes the recent development of studies about somatic mutation, molecular subtype, microenvironment heterogeneity, organoid, orthotopic model, patient-derived xenograft and clinical translation on GBC in aspects of genomic,transcriptome,single cell omics and clinical translation. We expect this review will provide new ideas on dissecting molecular mechanisms underlying the development and emerging chemoresistance of GBC following therapy and promote GBC precision medicine.


Assuntos
Humanos , Neoplasias da Vesícula Biliar/genética , Prognóstico , Microambiente Tumoral
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