Detalhe da pesquisa
1.
Structure-Based Discovery of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Induced Osteoclastogenesis Inhibitors.
Int J Mol Sci
; 24(14)2023 Jul 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37511048
2.
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.
J Proteome Res
; 21(2): 375-394, 2022 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34983179
3.
Novel insights into SLC25A46-related pathologies in a genetic mouse model.
PLoS Genet
; 13(4): e1006656, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28376086
4.
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
J Proteome Res
; 18(11): 3896-3912, 2019 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31550165
5.
Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution.
Neurochem Res
; 44(1): 154-169, 2019 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29777493
6.
Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).
PLoS Comput Biol
; 13(4): e1005372, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28426652
7.
A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF.
Hum Mol Genet
; 21(4): 784-98, 2012 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22068587
8.
2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.
Bioorg Med Chem
; 22(15): 3957-70, 2014 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25002233
9.
Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects.
Arch Pharm (Weinheim)
; 347(11): 798-805, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25160057
10.
A perspective on muscle phenotyping in musculoskeletal research.
Trends Endocrinol Metab
; 2024 03 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38553405
11.
A statistical approach for optimization of RANKL overexpression in Escherichia coli: purification and characterization of the protein.
Protein Expr Purif
; 90(1): 9-19, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23623854
12.
Phosphotungstic acid-enhanced microcomputed tomography for quantitative visualization of mouse mammary gland morphology.
J Med Imaging (Bellingham)
; 10(Suppl 2): S22402, 2023 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-36825256
13.
Inhibition Analysis and High-Resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1.
Biomolecules
; 13(4)2023 03 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37189361
14.
Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics.
Cancers (Basel)
; 15(15)2023 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37568820
15.
RANKL-Induced Increase in Cathepsin K Levels Restricts Cortical Expansion in a Periostin-Dependent Fashion: A Potential New Mechanism of Bone Fragility.
J Bone Miner Res
; 36(8): 1636-1645, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33856714
16.
Dexamethasone Administration in Mice Leads to Less Body Weight Gain over Time, Lower Serum Glucose, and Higher Insulin Levels Independently of NRF2.
Antioxidants (Basel)
; 11(1)2021 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-35052508
17.
Bone Phenotyping Approaches in Human, Mice and Zebrafish - Expert Overview of the EU Cost Action GEMSTONE ("GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork").
Front Endocrinol (Lausanne)
; 12: 720728, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34925226
18.
Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques.
Front Endocrinol (Lausanne)
; 12: 731217, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34938269
19.
Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index.
J Med Chem
; 63(20): 12043-12059, 2020 10 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32955874
20.
Reporting Guidelines, Review of Methodological Standards, and Challenges Toward Harmonization in Bone Marrow Adiposity Research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society.
Front Endocrinol (Lausanne)
; 11: 65, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32180758