Detalhe da pesquisa
1.
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
Nat Cancer
; 4(5): 754-773, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37237081
2.
A clinically relevant pulse treatment generates a bortezomib-resistant myeloma cell line that lacks proteasome mutations and is sensitive to Bcl-2 inhibitor venetoclax.
Sci Rep
; 12(1): 12788, 2022 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-35896610
3.
Activity of immunoproteasome inhibitor ONX-0914 in acute lymphoblastic leukemia expressing MLL-AF4 fusion protein.
Sci Rep
; 11(1): 10883, 2021 05 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34035431
4.
M3258 Is a Selective Inhibitor of the Immunoproteasome Subunit LMP7 (ß5i) Delivering Efficacy in Multiple Myeloma Models.
Mol Cancer Ther
; 20(8): 1378-1387, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34045234
5.
Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins.
Cell Rep
; 34(1): 108532, 2021 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33406420