Detalhe da pesquisa
1.
Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high-grade gliomas.
Neuropathol Appl Neurobiol
; 49(4): e12915, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37296499
2.
Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.
Proc Natl Acad Sci U S A
; 115(52): E12285-E12294, 2018 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30538199
3.
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
J Neurosci
; 37(4): 893-905, 2017 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28123024
4.
Haploinsufficiency of the lysosomal sialidase NEU1 results in a model of pleomorphic rhabdomyosarcoma in mice.
Commun Biol
; 5(1): 992, 2022 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36127469
5.
Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair.
Neuron
; 109(24): 3962-3979.e6, 2021 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34655526
6.
Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage-induced neurodegeneration.
Sci Adv
; 7(51): eabg6363, 2021 Dec 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34910524
7.
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors.
Nat Commun
; 9(1): 4760, 2018 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30420702
8.
Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.
Nat Neurosci
; 17(6): 813-21, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24793032
9.
Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.
Nat Neurosci
; 15(6): 819-26, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22522401