Detalhe da pesquisa
1.
SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML.
Blood
; 122(8): 1455-63, 2013 Aug 22.
Artigo
Inglês
| MEDLINE | ID: mdl-23770776
2.
A phase I multidose study of dacetuzumab (SGN-40; humanized anti-CD40 monoclonal antibody) in patients with multiple myeloma.
Haematologica
; 95(5): 845-8, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20133895
3.
A randomized, multicenter study to determine the safety and efficacy of the immunoconjugate SGN-15 plus docetaxel for the treatment of non-small cell lung carcinoma.
Lung Cancer
; 54(1): 69-77, 2006 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16934909
4.
Congenital amegakaryocytic thrombocytopenia in three siblings: molecular analysis of atypical clinical presentation.
Exp Hematol
; 33(10): 1215-21, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16219544
5.
The molecular and cellular biology of thrombopoietin: the primary regulator of platelet production.
Oncogene
; 21(21): 3359-67, 2002 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-12032774
6.
X-linked thrombocytopenia caused by a mutation in the Wiskott-Aldrich syndrome (WAS) gene that disrupts interaction with the WAS protein (WASP)-interacting protein (WIP).
Exp Hematol
; 31(2): 150-8, 2003 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-12591280
7.
Identification and activation of Src family kinases in primary megakaryocytes.
Exp Hematol
; 31(12): 1268-74, 2003 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-14662334
8.
Gene expression profile of primary human CD34+CD38lo cells differentiating along the megakaryocyte lineage.
Exp Hematol
; 32(7): 638-48, 2004 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15246160
9.
Dacetuzumab plus rituximab, ifosfamide, carboplatin and etoposide as salvage therapy for patients with diffuse large B-cell lymphoma relapsing after rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone: a randomized, double-blind, placebo-controlled phase 2b trial.
Leuk Lymphoma
; 56(9): 2569-78, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25651427
10.
A phase II study of dacetuzumab (SGN-40) in patients with relapsed diffuse large B-cell lymphoma (DLBCL) and correlative analyses of patient-specific factors.
J Hematol Oncol
; 7: 44, 2014 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24919462
11.
Antibody-drug conjugates: the chemistry behind empowering antibodies to fight cancer.
Hematology Am Soc Hematol Educ Program
; 2013: 306-10, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24319196
12.
Pilot study of dacetuzumab in combination with rituximab and gemcitabine for relapsed or refractory diffuse large B-cell lymphoma.
Leuk Lymphoma
; 54(2): 277-83, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22775314
13.
A phase I study of dacetuzumab (SGN-40, a humanized anti-CD40 monoclonal antibody) in patients with chronic lymphocytic leukemia.
Leuk Lymphoma
; 51(2): 228-35, 2010 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20038235
14.
In vivo inactivation of MASTL kinase results in thrombocytopenia.
Exp Hematol
; 37(8): 901-8, 2009 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-19460416
15.
Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma.
J Clin Oncol
; 27(26): 4371-7, 2009 Sep 10.
Artigo
Inglês
| MEDLINE | ID: mdl-19636010
16.
Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial.
Leuk Lymphoma
; 50(8): 1336-44, 2009 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-19557623
17.
Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656.
Blood
; 105(10): 3875-8, 2005 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15677565
18.
A novel strategy for generating platelet-like fragments from megakaryocytic cell lines and human progenitor cells.
Blood Cells Mol Dis
; 35(1): 70-3, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-15923131
19.
Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation.
Blood
; 105(12): 4664-70, 2005 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15741216
20.
Inherited thrombocytopenia: when a low platelet count does not mean ITP.
Blood
; 103(2): 390-8, 2004 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-14504084