Detalhe da pesquisa
1.
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.
Mol Cell
; 57(2): 261-72, 2015 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25544560
2.
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
Pharm Res
; 39(11): 2871-2883, 2022 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-36195821
3.
Optimizing the aryl-triazole of cjoc42 for enhanced gankyrin binding and anti-cancer activity.
Bioorg Med Chem Lett
; 30(17): 127372, 2020 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32738965
4.
Structural modification of the aryl sulfonate ester of cjoc42 for enhanced gankyrin binding and anti-cancer activity.
Bioorg Med Chem Lett
; 30(4): 126889, 2020 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31902711
5.
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
Exp Cell Res
; 381(2): 288-300, 2019 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31128107
6.
Expression, purification and characterization of soluble red rooster laforin as a fusion protein in Escherichia coli.
BMC Biochem
; 15: 8, 2014 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-24690255
7.
Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione.
Apoptosis
; 18(6): 702-12, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23494481
8.
The effect of hormones insulin and glucagon on ubiquitin modifications elucidated by proteomics in liver cells.
Life Sci
; 329: 121935, 2023 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37442415
9.
Laforin, a dual-specificity phosphatase involved in Lafora disease, is phosphorylated at Ser25 by AMP-activated protein kinase.
Biochem J
; 439(2): 265-75, 2011 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21728993
10.
Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy.
Heliyon
; 8(1): e08702, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-35036599
11.
Metabolic alterations and mitochondrial dysfunction underlie hepatocellular carcinoma cell death induced by a glycogen metabolic inhibitor.
Biochem Pharmacol
; 203: 115201, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35926650
12.
Chronic hypoxia-induced alterations of key enzymes of glucose oxidative metabolism in developing mouse liver are mTOR dependent.
Mol Cell Biochem
; 357(1-2): 189-97, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21625955
13.
A novel gene therapy for neurodegenerative Lafora disease via EPM2A-loaded DLinDMA lipoplexes.
Nanomedicine (Lond)
; 16(13): 1081-1095, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33960213
14.
Development of Dual ARV-825 and Nintedanib-Loaded PEGylated Nano-Liposomes for Synergistic Efficacy in Vemurafnib-Resistant Melanoma.
Pharmaceutics
; 13(7)2021 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34371697
15.
Methods for Studying TNFα-Induced Autophagy.
Methods Mol Biol
; 2108: 131-146, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-31939177
16.
Nanoformulation of PROteolysis TArgeting Chimera targeting 'undruggable' c-Myc for the treatment of pancreatic cancer.
Nanomedicine (Lond)
; 15(18): 1761-1777, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32698663
17.
Synthesis and Biological Evaluation of Structurally Diverse Benzimidazole Scaffolds as Potential Chemotherapeutic Agents.
Anticancer Agents Med Chem
; 20(3): 301-314, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-31746304
18.
EphA2-Receptor Targeted PEGylated Nanoliposomes for the Treatment of BRAFV600E Mutated Parent- and Vemurafenib-Resistant Melanoma.
Pharmaceutics
; 11(10)2019 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31581483
19.
Nuclear Glycogenolysis Modulates Histone Acetylation in Human Non-Small Cell Lung Cancers.
Cell Metab
; 30(5): 903-916.e7, 2019 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31523006
20.
Recent advances in the application of nanomedicine for the treatment of diabetes.
Nanomedicine (Lond)
; 17(2): 65-69, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34983192