Detalhe da pesquisa
1.
The dystonia gene THAP1 controls DNA double-strand break repair choice.
Mol Cell
; 81(12): 2611-2624.e10, 2021 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33857404
2.
53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Mol Cell
; 77(1): 26-38.e7, 2020 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31653568
3.
Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.
Proc Natl Acad Sci U S A
; 115(52): E12285-E12294, 2018 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30538199
4.
Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.
EMBO J
; 34(19): 2465-80, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26290337
5.
Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes.
Nature
; 501(7468): 569-72, 2013 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-24013173
6.
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
J Neurosci
; 37(4): 893-905, 2017 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28123024
7.
Out of LINE: Transposons, genome integrity, and neurodegeneration.
Neuron
; 110(20): 3217-3219, 2022 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36265437
8.
Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage-induced neurodegeneration.
Sci Adv
; 7(51): eabg6363, 2021 Dec 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34910524
9.
TREX2 exonuclease defective cells exhibit double-strand breaks and chromosomal fragments but not Robertsonian translocations.
Mutat Res
; 662(1-2): 84-7, 2009 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-19094998
10.
Biochemical and cellular characteristics of the 3' -> 5' exonuclease TREX2.
Nucleic Acids Res
; 35(8): 2682-94, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17426129
11.
Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells.
Cancer Res
; 67(19): 9077-83, 2007 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17909011
12.
Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease.
Mech Ageing Dev
; 161(Pt A): 121-129, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27125728
13.
Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair.
Genetics
; 188(4): 787-97, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21546543
14.
HPRT minigene generates chimeric transcripts as a by-product of gene targeting.
Genesis
; 45(5): 275-81, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-17457929