Detalhe da pesquisa
1.
A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
J Biol Chem
; 300(4): 107163, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38484799
2.
Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region.
Biochemistry
; 62(11): 1631-1642, 2023 06 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37167199
3.
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Mol Ther
; 30(4): 1484-1499, 2022 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35007758
4.
Structural insight into the role of the PAS domainfor signal transduction in sensor-kinase BvgS.
J Bacteriol
; 203(9)2021 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33619154
5.
Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications.
Adv Exp Med Biol
; 1184: 35-45, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-32096026
6.
Conformational Changes of an Interdomain Linker Mediate Mechanical Signal Transmission in Sensor Kinase BvgS.
J Bacteriol
; 199(18)2017 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28507245
7.
Virulence regulation with Venus flytrap domains: structure and function of the periplasmic moiety of the sensor-kinase BvgS.
PLoS Pathog
; 11(3): e1004700, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25738876
8.
Signal Transduction by BvgS Sensor Kinase: BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY.
J Biol Chem
; 290(38): 23307-19, 2015 Sep 18.
Artigo
Inglês
| MEDLINE | ID: mdl-26203186
9.
Recombinant Production and Characterization of VHHs/Nanobodies Targeting Tau to Block Fibrillar Assembly.
Methods Mol Biol
; 2754: 131-146, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38512665
10.
Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation.
Biophys Chem
; 305: 107155, 2024 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38100856
11.
Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission.
BMC Microbiol
; 13: 172, 2013 Jul 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23883404
12.
Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism.
Proc Natl Acad Sci U S A
; 107(40): 17351-5, 2010 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-20855615
13.
Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.
Eur J Med Chem
; 250: 115186, 2023 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36796300
14.
Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools.
Front Chem
; 10: 886382, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35646824
15.
Signal transduction by BvgS sensor kinase. Binding of modulator nicotinate affects the conformation and dynamics of the entire periplasmic moiety.
J Biol Chem
; 290(44): 26473, 2015 Oct 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26519485
16.
Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies.
ACS Chem Neurosci
; 10(9): 3997-4006, 2019 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31380615
17.
Coiled-Coil Antagonism Regulates Activity of Venus Flytrap-Domain-Containing Sensor Kinases of the BvgS Family.
mBio
; 9(1)2018 02 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29487240
18.
Translocation path of a substrate protein through its Omp85 transporter.
Nat Commun
; 5: 5271, 2014 Oct 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25327833