Detalhe da pesquisa
1.
Challenges, approaches and enablers: effectively triangulating towards dose selection in pediatric rare diseases.
J Pharmacokinet Pharmacodyn
; 50(6): 445-459, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37296230
2.
Evaluation of pharmacokinetics and safety of talazoparib in patients with advanced cancer and varying degrees of hepatic impairment.
Br J Clin Pharmacol
; 88(7): 3392-3403, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35236002
3.
Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer.
Anticancer Drugs
; 29(3): 271-280, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29360661
4.
Ocular Pharmacokinetics.
Handb Exp Pharmacol
; 242: 31-55, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-27787714
5.
Mechanism - based translational pharmacokinetic - pharmacodynamic model to predict intraocular pressure lowering effect of drugs in patients with glaucoma or ocular hypertension.
Pharm Res
; 31(8): 2095-106, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24549827
6.
International consortium for innovation and quality: An industry perspective on the nonclinical and early clinical development of intravitreal drugs.
Clin Transl Sci
; 16(5): 723-741, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36651217
7.
Intraocular distribution of melanin in human, monkey, rabbit, minipig and dog eyes.
Exp Eye Res
; 98: 23-7, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22440812
8.
Impact of Dose Reduction on Efficacy: Implications of Exposure-Response Analysis of Palbociclib.
Target Oncol
; 16(1): 69-76, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33211314
9.
The Effect of Renal Impairment on the Pharmacokinetics and Safety of Talazoparib in Patients with Advanced Solid Tumors.
Clin Pharmacokinet
; 60(7): 921-930, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33686631
10.
Population Pharmacokinetics of Talazoparib in Patients With Advanced Cancer.
J Clin Pharmacol
; 60(2): 218-228, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31489639
11.
Prediction of vitreal half-life based on drug physicochemical properties: quantitative structure-pharmacokinetic relationships (QSPKR).
Pharm Res
; 26(5): 1236-60, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18841448
12.
Human scleral diffusion of anticancer drugs from solution and nanoparticle formulation.
Pharm Res
; 26(5): 1155-61, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19194787
13.
Distribution, Metabolism, and Excretion of Gedatolisib in Healthy Male Volunteers After a Single Intravenous Infusion.
Clin Pharmacol Drug Dev
; 8(1): 22-31, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30256541
14.
Optimal sampling scheme for estimation of intraocular pressure diurnal curves in glaucoma trials.
Clin Pharmacokinet
; 54(1): 95-105, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25227284
15.
Comparison of long-acting bevacizumab formulations in the treatment of choroidal neovascularization in a rat model.
J Ocul Pharmacol Ther
; 27(3): 219-24, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21574814
16.
Nanosized dendritic polyguanidilyated translocators for enhanced solubility, permeability, and delivery of gatifloxacin.
Invest Ophthalmol Vis Sci
; 51(11): 5804-16, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20484584
17.
Luteinizing hormone-releasing hormone receptor-targeted deslorelin-docetaxel conjugate enhances efficacy of docetaxel in prostate cancer therapy.
Mol Cancer Ther
; 8(6): 1655-65, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19509261
18.
Influence of dosage form on the intravitreal pharmacokinetics of diclofenac.
Invest Ophthalmol Vis Sci
; 50(10): 4887-97, 2009 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-19516015
19.
Subconjunctival nanoparticle carboplatin in the treatment of murine retinoblastoma.
Arch Ophthalmol
; 127(8): 1043-7, 2009 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-19667343
20.
Targeted drug and gene delivery systems for lung cancer therapy.
Clin Cancer Res
; 15(23): 7299-308, 2009 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19920099