Detalhe da pesquisa
1.
Tau accumulates in Crohn's disease gut.
FASEB J
; 34(7): 9285-9296, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32436623
2.
A Collection of Bioactive Nitrogen-Containing Molecules from the Marine Sponge Acanthostrongylophora ingens.
Mar Drugs
; 17(8)2019 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31443260
3.
Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.
Mar Drugs
; 15(10)2017 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29039762
4.
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Antimicrob Agents Chemother
; 60(5): 2822-33, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26902771
5.
cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.
Mol Pharmacol
; 85(3): 441-50, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24366666
6.
Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
Antimicrob Agents Chemother
; 58(3): 1501-15, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24366737
7.
Enteric alpha-synuclein expression is increased in Crohn's disease.
Acta Neuropathol
; 137(2): 359-361, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30506319
8.
New 5-ylidene rhodanine derivatives based on the dispacamide A model.
Mol Divers
; 18(2): 375-88, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24584455
9.
Role of ICAM-1 in the Adhesion of T Cells to Enteric Glia: Perspectives in the Formation of Plexitis in Crohn's Disease.
Cell Mol Gastroenterol Hepatol
; 18(1): 133-153, 2024 Feb 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38428588
10.
An efficient approach to dispacamide A and its derivatives.
Org Biomol Chem
; 10(5): 978-87, 2012 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22159215
11.
Library-based discovery of DYRK1A/CLK1 inhibitors from natural product extracts.
Planta Med
; 78(10): 951-6, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22673832
12.
Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis.
Cells
; 11(4)2022 02 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35203241
13.
Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors.
J Med Chem
; 65(2): 1396-1417, 2022 01 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34928152
14.
Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A.
Pharmaceuticals (Basel)
; 14(11)2021 Oct 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34832868
15.
Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase.
Bioorg Med Chem Lett
; 20(9): 2801-5, 2010 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20363627
16.
Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy.
Acta Neuropathol Commun
; 6(1): 65, 2018 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30037345
17.
Induction of Amyloid-ß42 Production by Fipronil and Other Pyrazole Insecticides.
J Alzheimers Dis
; 62(4): 1663-1681, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29504531
18.
Specific Triazine Herbicides Induce Amyloid-ß42 Production.
J Alzheimers Dis
; 54(4): 1593-1605, 2016 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27589520
19.
Dispacamide E and other bioactive bromopyrrole alkaloids from two Indonesian marine sponges of the genus Stylissa.
Nat Prod Res
; 29(3): 231-8, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25116895
20.
Synthesis, resolution, and biological evaluation of atropisomeric (aR)- and (aS)-16-methyllamellarins N: unique effects of the axial chirality on the selectivity of protein kinases inhibition.
J Med Chem
; 56(18): 7289-301, 2013 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-23981088