RESUMO
The human herpes virus (HHV) family (herpesviridae) are large DNA viruses containing eight important, ubiquitous human pathogens. This group of viruses encompasses: herpes simplex virus (HSV types 1 and 2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), HHV-6, HHV-7 (cause roseola or exanthema subitum in children) and Kaposi sarcoma herpes virus--(KSHV). The outstanding property of herpes viruses is lifelong persistence of infection and potential periodic reactivation, particularly often among immunocompromised patients. Herpesvirus infections are associated with a wide spectrum of diseases ranging from local ulceration to serious systemic illnessess or malignancies. These infections are one of the major cause of morbidity and mortality in the immunocompromised patients.
Assuntos
Transplante de Medula Óssea/imunologia , Infecções por Herpesviridae/imunologia , Hospedeiro Imunocomprometido/imunologia , Transplante de Órgãos/estatística & dados numéricos , Antivirais/uso terapêutico , Transplante de Medula Óssea/estatística & dados numéricos , Infecções por Herpesviridae/tratamento farmacológico , Infecções por Herpesviridae/epidemiologia , Humanos , RecidivaRESUMO
The most common metabolic disorder of hem biosynthesis is porphyria cutanea tarda (PCT). PCT frequently is connected with liver disfunction. We have shown three cases of patients suffering from PCT and HCV infection, treated in Department of Infectious Diseases of Medical University in Wroclaw. There is shown the pathway from the first disorders to the diagnosis and influence of treatment on the course of disease.