Detalhe da pesquisa
1.
Proteogenomic characterization of pancreatic ductal adenocarcinoma.
Cell
; 184(19): 5031-5052.e26, 2021 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34534465
2.
Combining EZH2 and HDAC inhibitors to target castration-resistant prostate cancers.
PLoS Biol
; 21(4): e3002081, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37104249
3.
Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
Nature
; 579(7798): 284-290, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32103175
4.
Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers.
Proc Natl Acad Sci U S A
; 120(31): e2301536120, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37487069
5.
Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress.
Mol Cell
; 65(2): 323-335, 2017 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-28107650
6.
Epigenetic dynamics of aging and cancer development: current concepts from studies mapping aging and cancer epigenomes.
Curr Opin Oncol
; 36(2): 82-92, 2024 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38441107
7.
Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance.
Mol Cell
; 54(5): 716-27, 2014 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-24905005
8.
Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets.
Nucleic Acids Res
; 48(12): e68, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32392348
9.
A DNA hypermethylation module for the stem/progenitor cell signature of cancer.
Genome Res
; 22(5): 837-49, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22391556
10.
DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes.
Nucleic Acids Res
; 40(10): 4334-46, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22278882
11.
Tissue-location-specific transcription programs drive tumor dependencies in colon cancer.
Nat Commun
; 15(1): 1384, 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38360902
12.
Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies.
Commun Biol
; 7(1): 35, 2024 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38182665
13.
Genetic and epigenetic dependencies in colorectal cancer development.
Gastroenterol Rep (Oxf)
; 10: goac035, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35975243
14.
Evaluating the impact of age on immune checkpoint therapy biomarkers.
Cell Rep
; 36(8): 109599, 2021 08 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34433020
15.
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation.
J Cell Biol
; 169(5): 733-43, 2005 Jun 06.
Artigo
Inglês
| MEDLINE | ID: mdl-15939760
16.
DNA methylation analysis on a droplet-in-oil PCR array.
Lab Chip
; 9(8): 1059-64, 2009 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-19350087
17.
Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties.
Cancer Cell
; 35(4): 633-648.e7, 2019 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30956060
18.
Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis.
Cancer Cell
; 35(2): 315-328.e6, 2019 02 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30753828
19.
A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine.
Cancer Res
; 78(5): 1127-1139, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29282222
20.
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis.
Brief Funct Genomics
; 17(1): 49-63, 2018 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28968850