Detalhe da pesquisa
1.
Bifunctional TGF-ß trap/IL-15 protein complex elicits potent NK cell and CD8+ T cell immunity against solid tumors.
Mol Ther
; 29(10): 2949-2962, 2021 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34091051
2.
First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation.
Blood
; 131(23): 2515-2527, 2018 06 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29463563
3.
ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment.
J Virol
; 92(3)2018 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29118125
4.
ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial.
Lancet Oncol
; 19(5): 694-704, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29628312
5.
A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice.
Front Immunol
; 14: 1114802, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36761778
6.
Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Aging Cell
; 22(5): e13806, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36967480
7.
Novel human interleukin-15 agonists.
J Immunol
; 183(6): 3598-607, 2009 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19710453
8.
A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy.
Cancer Immunol Res
; 9(9): 1071-1087, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34244297
9.
Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors.
Clin Cancer Res
; 24(22): 5552-5561, 2018 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30045932
10.
Comparison of the Superagonist Complex, ALT-803, to IL15 as Cancer Immunotherapeutics in Animal Models.
Cancer Immunol Res
; 4(1): 49-60, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26511282
11.
Intravesical ALT-803 and BCG treatment reduces tumor burden in a carcinogen induced bladder cancer rat model; a role for cytokine production and NK cell expansion.
PLoS One
; 9(6): e96705, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24896845
12.
Inhibition of acute vascular thrombosis in chimpanzees by an anti-human tissue factor antibody targeting the factor X binding site.
Thromb Haemost
; 103(1): 224-33, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20062929