Detalhe da pesquisa
1.
Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Proc Natl Acad Sci U S A
; 110(36): E3445-54, 2013 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-23946421
2.
Hydrogen exchange-mass spectrometry measures stapled peptide conformational dynamics and predicts pharmacokinetic properties.
Anal Chem
; 85(23): 11185-8, 2013 Dec 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24215480
3.
Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
J Med Chem
; 66(14): 9401-9417, 2023 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37439511
4.
Cross-docking of inhibitors into CDK2 structures. 2.
J Chem Inf Model
; 48(3): 669-78, 2008 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-18324800