Detalhe da pesquisa
1.
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol Cell
; 83(15): 2753-2767.e10, 2023 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37478846
2.
MEN1 mutations mediate clinical resistance to menin inhibition.
Nature
; 615(7954): 913-919, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36922589
3.
Persistent Fibroadipogenic Progenitor Expansion Following Transient DUX4 Expression Provokes a Profibrotic State in a Mouse Model for FSHD.
Int J Mol Sci
; 23(4)2022 Feb 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35216102
4.
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
bioRxiv
; 2023 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36711898
5.
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
iScience
; 26(10): 107823, 2023 Oct 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37744032
6.
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.
Oncogenesis
; 10(10): 68, 2021 Oct 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34642317
7.
Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice.
J Clin Invest
; 130(5): 2465-2477, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32250341
8.
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death.
Sci Adv
; 5(9): eaaw7781, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31535023
9.
Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression.
Sci Rep
; 8(1): 16957, 2018 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30446688