Detalhe da pesquisa
1.
Species differences in plasma protein binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease inhibitor nirmatrelvir.
Xenobiotica
; 53(1): 12-24, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36803165
2.
Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.
Drug Metab Dispos
; 2022 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35777846
3.
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans.
Drug Metab Dispos
; 50(5): 576-590, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35153195
4.
Organic Anion-Transporting Polypeptide 1B1/1B3-Mediated Hepatic Uptake Determines the Pharmacokinetics of Large Lipophilic Acids: In Vitro-In Vivo Evaluation in Cynomolgus Monkey.
J Pharmacol Exp Ther
; 377(1): 169-180, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33509903
5.
Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes.
Drug Metab Dispos
; 49(10): 947-960, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34326140
6.
Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19: The ACTIV-4B Randomized Clinical Trial.
JAMA
; 326(17): 1703-1712, 2021 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34633405
7.
Cytochrome P450 3A Time-Dependent Inhibition Assays Are Too Sensitive for Identification of Drugs Causing Clinically Significant Drug-Drug Interactions: A Comparison of Human Liver Microsomes and Hepatocytes and Definition of Boundaries for Inactivation Rate Constants.
Drug Metab Dispos
; 49(6): 442-450, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33811106
8.
Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1.
Drug Metab Dispos
; 47(5): 493-503, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30862625
9.
Parent Training for Feeding Problems in Children With Autism Spectrum Disorder: Initial Randomized Trial.
J Pediatr Psychol
; 44(2): 164-175, 2019 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30101320
10.
Influenza Vaccine Intention After a Medically Attended Acute Respiratory Infection.
Health Promot Pract
; 20(4): 539-552, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30005579
11.
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to ß-Estradiol.
Drug Metab Dispos
; 46(12): 1836-1846, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30194276
12.
Mood symptoms in pregnant and postpartum women with bipolar disorder: a naturalistic study.
Bipolar Disord
; 19(4): 295-304, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28665044
13.
Comparative pharmacokinetic profile of cyclosporine (CsA) with a decapeptide and a linear analogue.
Org Biomol Chem
; 15(12): 2501-2506, 2017 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28266673
14.
Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.
Angew Chem Int Ed Engl
; 56(51): 16218-16222, 2017 12 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29073340
15.
Use of Human Plasma Samples to Identify Circulating Drug Metabolites that Inhibit Cytochrome P450 Enzymes.
Drug Metab Dispos
; 44(8): 1217-28, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27271369
16.
The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide-Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy.
Drug Metab Dispos
; 44(5): 692-9, 2016 May.
Artigo
Inglês
| MEDLINE | ID: mdl-26888941
17.
Species Differences in the Oxidative Desulfurization of a Thiouracil-Based Irreversible Myeloperoxidase Inactivator by Flavin-Containing Monooxygenase Enzymes.
Drug Metab Dispos
; 44(8): 1262-9, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27079250
18.
Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis.
Chem Res Toxicol
; 29(10): 1778-1788, 2016 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27676153
19.
Classification and Regression Tree (CART) analysis to predict influenza in primary care patients.
BMC Infect Dis
; 16(1): 503, 2016 Sep 22.
Artigo
Inglês
| MEDLINE | ID: mdl-27659721
20.
The prevalence of rapid weight gain in infancy differs by the growth reference and age interval used for evaluation.
Ann Hum Biol
; 43(1): 85-90, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26065692