Detalhe da pesquisa
1.
Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
Lancet Oncol
; 25(5): 668-682, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38552658
2.
Phenelzine protects against acetaminophen induced apoptosis in HepG2 cells.
Drug Chem Toxicol
; 47(1): 81-89, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37246945
3.
4-{3-[(Pyridin-4-ylmethyl)amino]-[1,2,4]triazolo[4,3-b][1,2,4]triazin-6-yl}phenol: An improved anticancer agent in hepatocellular carcinoma and a selective MDR1/MRP modulator.
Arch Pharm (Weinheim)
; 357(6): e2300704, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38442326
4.
Synthesis, computational molecular docking analysis and effectiveness on tyrosinase inhibition of kojic acid derivatives.
Bioorg Chem
; 88: 102950, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31075740
5.
Recurrent posterior fossa group A (PFA) ependymoma in a young child with constitutional mismatch repair deficiency (CMMRD).
Neuropathol Appl Neurobiol
; 49(1): e12862, 2023 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-36341503
6.
Diffusion-weighted chemical shift imaging of human brain metabolites at 7T.
Magn Reson Med
; 73(6): 2053-61, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24986121
7.
Reproducibility and optimization of in vivo human diffusion-weighted MRS of the corpus callosum at 3 T and 7 T.
NMR Biomed
; 28(8): 976-987, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26084563
8.
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discov
; 14(2): 258-273, 2024 Feb 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37823831
9.
Evaluation of selective human MAO inhibitory activities of some novel pyrazoline derivatives.
J Neural Transm (Vienna)
; 120(6): 863-73, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23361656
10.
Effects of single or combined exposure to bisphenol A and mono(2-ethylhexyl)phthalate on oxidant/antioxidant status, endoplasmic reticulum stress, and apoptosis in HepG2 cell line.
Environ Sci Pollut Res Int
; 30(5): 12189-12206, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36104651
11.
Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency.
Clin Cancer Res
; 29(23): 4770-4783, 2023 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37126021
12.
A different approach to immunochemotherapy for colon Cancer: Development of nanoplexes of cyclodextrins and Interleukin-2 loaded with 5-FU.
Int J Pharm
; 623: 121940, 2022 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35724824
13.
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.
Nat Med
; 28(1): 125-135, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34992263
14.
Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies.
Bioorg Med Chem Lett
; 21(14): 4296-300, 2011 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21680183
15.
Polycationic cyclodextrin nanoparticles induce apoptosis and affect antitumoral activity in HepG2 cell line: An evaluation at the molecular level.
Int J Pharm
; 598: 120379, 2021 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33592288
16.
Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.
J Clin Oncol
; 39(25): 2779-2790, 2021 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33945292
17.
Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade.
Cancer Res
; 80(24): 5606-5618, 2020 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32938641
18.
Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors.
Bioorg Med Chem
; 17(18): 6761-72, 2009 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19682910
19.
A kojic acid derivative promotes intrinsic apoptotic pathway of hepatocellular carcinoma cells without incurring drug resistance.
Chem Biol Drug Des
; 94(6): 2084-2093, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31495064
20.
Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma.
Anticancer Agents Med Chem
; 19(17): 2120-2129, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31393257