Varus mechanism is associated with high incidence of popliteal artery lesions in multiligament knee injuries.

PURPOSE: This study aims to identify multiple ligament knee injury patterns that possess a high-risk of vascular lesion. METHODS: We retrospectively compared torn ligament patterns and the presence of vascular lesions confirmed by magnetic resonance imaging and computed tomography angiography from 122 consecutive patients with diagnoses of multiple ligament knee injury made at the emergency department between January 2012 and December 2017. Patients were not eligible if they had an ipsilateral lower extremity lesion (dislocations or fractures at another level), initial evaluation at another hospital, or follow-up for less than 12 months. The primary outcomes were the comparison between the imaging findings of torn structures patterns and the presence of a vascular lesion. RESULTS: We identified 48 eligible patients (50 knees) with multiligamentary knee lesions, of whom eight had popliteal artery damage, yielding an incidence of 16%. Our clinical examination detected six of these patients that were classified, according to the Schenck system, as KD-IIIL (6 knees) and KD-IIIM (2 knees). The odds of having a popliteal artery injury is 4.69 to 1 with a KD-IIIL injury that with any other type of injury on that classification (95% CI 0.960-22.98). CONCLUSIONS: This data suggests that varus forces causing enough energy to produce a KD-IIIL lesion possess a higher popliteal artery injury risk, making recommendable a thorough examination of the vascular integrity when diagnosing a KD-IIIL lesion.

[Chronic granulomatous disease: three cases with different presentations]. / Enfermedad granulomatosa crónica: tres casos clínicos con diferentes formas de presentación.

INTRODUCTION: Chronic granulomatous disease (CGD) is a rare form of primary immunodeficiency disease, characterized by an abnormal susceptibility to bacterial and fungal infections, and it is caused by a deficit in the phagocyte nicotinamide adenine dinucleotide phosphate oxidase complex (NADPH), resulting in the inability to generate reactive oxygen species that destroy microorganisms. The diagnosis is based on clinical characteristics and analysis of phagocytes, and later confirmed by molecular studies. Its management should consider antimicrobial prophylaxis, a search for infections and aggressive management of these. OBJECTIVE: To describe three cases of CGD emphasizing their forms of presentation and to conduct a review of the condition. CASE REPORTS: Three case reports, two of them first cousins, are presented. Molecular diagnosis was reached in one of the cases. Recurrent infections, abscesses, adenitis, granulomas and complications are identified to facilitate the suspected diagnosis of CGD, bearing in mind the importance of early diagnosis and genetic counseling. CONCLUSIONS: EGC is a rare congenital primary immunodeficiency disorder, mostly with X-linked inheritance, autosomal recessive form, and a specific presentation form. Its diagnosis should be timely to avoid complications. Prophylaxis and aggressive treatment of infections should be performed, as well as genetic counseling.

ADAM: a robotic companion for enhanced quality of life in aging populations.

One of the major problems of today's society is the rapid aging of its population. Life expectancy is increasing, but the quality of life is not. Faced with the growing number of people who require cognitive or physical assistance, new technological tools are emerging to help them. In this article, we present the ADAM robot, a new robot designed for domestic physical assistance. It mainly consists of a mobile base, two arms with grippers and vision systems. All this allows the performance of physical tasks that require navigation and manipulation of the environment. Among ADAM's features are its modularity, its adaptability to indoor environments and its versatility to function as an experimental platform and for service applications. In addition, it is designed to work respecting the user's personal space and is collaborative, so it can learn from experiences taught by them. We present the design of the robot as well as examples of use in domestic environments both alone and in collaboration with other domestic platforms, demonstrating its potential.

Ionizing Radiation-Induced Oxidative Stress in Computed Tomography-Effect of Vitamin C on Prevention of DNA Damage: PREVIR-C Randomized Controlled Trial Study Protocol.

Exposure to ionizing radiation (IR) is inevitable in various X-ray imaging examinations, with computed tomography (CT) being a major contributor to increased human radiation exposure. Ionizing radiation may cause structural damage to macromolecules, particularly DNA, mostly through an indirect pathway in diagnostic imaging. The indirect pathway primarily involves the generation of reactive oxygen species (ROS) due to water radiolysis induced by IR, leading to DNA damage, including double-strand breaks (DSB), which are highly cytotoxic. Antioxidants, substances that prevent oxidative damage, are proposed as potential radioprotective agents. This Study Protocol article presents the rationale for selecting vitamin C as a preventive measure against CT-associated IR-induced DNA damage, to be investigated in a randomized placebo-controlled trial, with a full in vivo design, using an oral easy-to-use schedule administration in the outpatient setting, for the single CT examination with the highest total global IR dose burden (contrast-enhanced abdomen and pelvis CT). The study also aims to explore the mediating role of oxidative stress, and it has been written in adherence to the Standard Protocol Items recommendations.

Medial femoral condyle fracture during an Oxford unicompartmental knee replacement surgery: case report.

Oxford unicompartmental knee arthroplasty has been used as a good alternative for medial unicompartmental osteoarthritis due to its association with early rehabilitation and a low rate of intraoperative complications. This case describes a rare complication during the procedure of an intraoperative fracture of the medial condyle that was treated with osteosynthesis with 6.5 mm cannulated screws and a compression technique. The patient followed a non-weight-bearing protocol for 6 weeks and reached full range of motion at 3 months. Complete radiological fusion and good functional outcome were observed. Intraoperative fractures can benefit from stable osteosynthesis that allows free range of motion and does not jeopardise the final surgical result.

Multiligamentary Reconstruction in a Below-Knee Amputation Patient.

Multiligament injuries in below-knee amputation patients are a severe condition, and its treatment is controversial. Its incidence is unknown, and it is highly underdiagnosed, representing a challenge for the physician. The case presented is about a patient with a left transtibial amputation secondary to a severe crushing of the ipsilateral lower limb to which during the process of physiotherapy, a multiligament injury was diagnosed. The patient underwent a tibiofibular fixation with a multiligament reconstruction with good functional results. In this complex situation, delay in diagnosis is frequent, ligament instability should always be suspected and explored further, allowing for proper rehabilitation and early treatment.

No association between positive intraoperative allograft cultures and infection rates after reconstructive knee ligament surgery.

BACKGROUND: Several reports of severe infections associated with allograft tissue in knee reconstructive surgery have led many surgeons to consider routine intraoperative culture of allograft tissue before implantation. Thus, the purpose of this study was to determine the prevalence of positive soft tissue allograft cultures in reconstructive knee surgery, and evaluate its association with surgical site infection. METHODS: Retrospective study of 202 patients who underwent knee reconstructive ligament surgeries, including revisions, between January 2013 and July 2017. Intraoperative culture results were obtained and the report of a surgical site infection during follow-up was recorded. Patients without cultures were excluded. A priori power analysis was performed. The association between positive culture results and development of surgical site infection was evaluated using Fisher's Exact test (P < 0.05). RESULTS: A total of 300 allografts were implanted in 202 patients. Mean average follow-up was 32.9 ±â€¯12.5 (range 13 to 57.9) months. Sixteen patients had positive intraoperative allograft cultures (7.9%). The most frequently isolated organism was Bacillus species (six cultures); none of these patients presented with clinical signs of infection. Nine patients developed surgical site infections and were treated with oral antibiotics, and one patient developed septic arthritis that required surgical debridement of the implanted graft; all of these patients had a negative soft tissue allograft culture. No significant association was found between a positive culture and surgical site infection (P = 0.43). CONCLUSION: There was no apparent association between positive intraoperative irradiated soft tissue allograft cultures and surgical site infection in reconstructive knee surgery.

Fracturas avulsivas tibiales del ligamento cruzado posterior fijadas con tornillos: un estudio clínico y radiológico / Screw fixation of posterior cruciate ligament tibial avulsion fractures: a clinical and radiographic study

OBJETIVO: Realizar la evaluación clínica, imagenológica y funcional de pacientes con fracturas avulsivas tibiales del ligamento cruzado posterior (FTALCPs) fijadas con tornillos canulados con técnica abierta. MÉTODOS: Los pacientes con FTALCP operados entre 2010 y 2017 fueron revisados retrospectivamente. Criterios de inclusión: fracturas agudas, desplazadas, test de cajón posterior grado III, lesiones combinadas de rodilla, seguimiento > 12 meses. Se excluyeron pacientes > 65 años, con FTALCPs bilaterales, lesiones del ligamento cruzado posterior (LCP) intrasustancia, test de cajón posterior grados I-II, fracturas expuestas, lesiones neurovasculares, y seguimientos < 12 meses. Objetivo primario: medir la estabilidad clínica mediante test de cajón posterior y radiografía de estrés arrodillada comparativa. Objetivos secundarios: nvaluar la consolidación en radiografías, complicaciones y funcionalidad con las escalas de Lysholm y Tegner. Resultados Se incluyeron 20 pacientes, con edad media de 41 años (rango: 32 a 61 años). El seguimiento promedio fue de 33,9 meses (rango: 12 a 82 meses). La estabilidad clínica mejoró en 93% (cajón posterior postoperatorio grados 0 y I) de los pacientes. La radiografía de estrés arrodillada mostró una diferencia promedio de 2,6 mm (rango: 0,1 mm a 6,8 mm) de traslación posterior al comparar con el lado sano. Todas las fracturas consolidaron. Siete pacientes presentaron complicaciones. El puntaje promedio de la escala de Lysholm al final del seguimiento fue de 85,17. El promedio preoperatorio del puntaje en la escala de Tegner no varió significativamente en comparación con el postoperatorio. CONCLUSIONES: La fijación de fracturas avulsivas tibiales del LCP con tornillos canulados con técnica abierta es efectiva en restaurar la estabilidad posterior y lograr la consolidación ósea. La funcionalidad clínica a mediano plazo es buena, a pesar del alto número de complicaciones y lesiones concomitantes. NIVEL DE EVIDENCIA: tipo IV.

OBJECTIVE: To report mid-term clinical, radiographic, and functional outcomes following open reduction and fixation of posterior cruciate ligament tibial avulsion fractures (PCLTAFs) with cannulated screws. METHODS: This is a retrospective analysis of patients with PCLTAF operated on from August 2010 to April 2017. Patients with acute fractures, with more than 2 mm of displacement and grade III on the posterior drawer test, combined or not to knee injuries, were included. Patients older than 65 years of age, with bilateral avulsion fractures, intrasubstance posterior cruciate ligament (PCL) lesions, stable grade-I to -II on the posterior drawer test, concomitant neurovascular injuries, mid-substance tears, open fractures, and less than 12 months of follow-up were excluded. Primary outcomes: the clinical stability was assessed using the posterior drawer test and a single comparative knee stress radiograph. Secondary outcomes: radiographic consolidation, complications, Lysholm score, and Tegner activity score. RESULTS: In total, 20 patients with a mean age of 41 years (range: 32 to 61 years) were included. The mean follow-up was of 33.9 months (range: 12 to 82 months). Clinical stability (grade 0 or I on the posterior drawer test) was observed in 93% of the patients. The mean difference in contralateral posterior displacement was of 2.6 mm (range: 0.1 mm to 6.8 mm) on a single comparative knee stress radiograph. All fractures presented radiological consolidation. Seven patients developed complications. The mean Lysholm score at the last follow-up visit was of 85.17. The postoperative Tegner activity scores did no vary significantly compared to the preinjury scores. CONCLUSIONS: Cannulated screw fixation of a displaced PCLTAF through a posterior approach restores clinical and radiographic stability and has excellent union rates. The mid-term functional outcomes are good despite the high rates of combined knee lesions and postoperative complications. LEVEL OF EVIDENCE: IV.

Tendencias en reconstrucción en ligamento cruzado anterior: encuesta a 103 cirujanos / Anterior cruciate ligament reconstruction tendencies among 103 surgeons

OBJETIVO: Describir las tendencias en reconstrucción de LCA (R-LCA) entre los traumatólogos ejerciendo en Chile, delineando sus preferencias en cuanto a la técnica quirúrgica. MÉTODO: encuesta online de selección múltiple y recolección anónima de datos, dirigida a todos aquellos cirujanos que realizan R-LCA en Chile. Fue enviada por correo electrónico desde la Sociedad Chilena de Ortopedia y Traumatología a todos sus afiliados. RESULTADOS: 103 cirujanos completaron la encuesta, realizando su práctica quirúrgica en Santiago (53%) y regiones (47%). En el 53% de los encuestados la cirugía de rodilla representaba más del 75% de su práctica, mientras que sólo en 9 ellas eran menos del 25%. El autoinjerto de isquiotibiales es utilizado en el 70% de R-LCA, seguido por el autoinjerto de tendón patelar (27%). En cuanto a la preparación de túneles, 33% utiliza técnica transtibial y 67% túneles independientes (13% fresado retrógrado, 54% portal medial). Para la fijación de injerto isquiotibiales, botones corticales es lo más utilizado en el fémur (73%), y tornillos interferenciales en la tibia (82%). Para la fijación femoral y tibial de injerto de tendón patelar, los tornillos metálicos son los más utilizados (75%). Un 41% realiza un pretensado del injerto, un 59% lo ciclan una vez fijo, y sólo 8 aplican una solución antibiótica sobre el injerto. La mayoría (89%) realiza la fijación en 10°-20° de flexión, ya sea con rotación externa (36%) o neutra (53%). En un 7% de las R-LCA primarias y en un 27% de las revisiones agregan una reconstrucción anterolateral. CONCLUSIÓN: la tendencia en R-LCA en Chile es el uso de autoinjerto de isquiotibiales, con fresado independiente del túnel femoral y fijación en flexión con botones corticales y tornillos interferenciales.

OBJECTIVE: To describe the trends in anterior cruciate ligament reconstruction (ACL-R) among Orthopaedic surgeons working in Chile, outlining their preferences regarding surgical technique. METHOD: An online, multiple choice, anonymous survey was sent via email from the Chilean Orthopaedic and Trauma Society to all its members, with instructions to be completed by surgeons who perform ACL-R. RESULTS: 103 surgeons completed the survey from Santiago (53%) and other regions (47%). For 53% of the surgeons, knee surgeries represented more than 75% of their practice, and in only 9 cases it was less than 25% of it. The autologous hamstring tendon graft was in 70% of the ACL-R, while patellar tendon graft in 27%. For tunnel drilling, 33% of surgeons use transtibial technique, and 67% prefer independent tunnel drilling (13% retrodrill, 54% medial portal). Fixation method for hamstring tendon graft is mostly with cortical buttons on femur (73%), and interference screws for the tibia (82%). Patellar graft was fixed with metal screws (75%) in both femur and tibia. 41% of surgeons pretensed the graft, 59% cycle it once, and only 8 coated the graft with antibiotic solutions. Most (89%) fixate de graft in 10°-20° of knee flexion, with either external rotation (36%) or neutral (53%). Antero-lateral reconstruction is used in 7% of primary ACL-R and in 27% of revision surgeries. CONCLUSION: the chilean tendency for ACL-R is to use an autologous hamstring tendon graft, with independent drilling technique, and fixation with cortical buttons and interference screws for femur and tibia respectively.

Anterior cruciate ligament reconstruction in patients over 50 years of age.

PURPOSE: To describe the clinical outcomes of patients over 50 years of age with following anterior cruciate ligament (ACL)reconstruction for acute rupture. METHODS: A prospective series of patients over the age of 50 years with a diagnosis of ACL rupture who underwent ACL reconstruction was examined. Lysholm and International Knee Documenting Committee (IKDC) subjective scores were assessed preoperatively and at the final follow-up. All associated injuries were documented, and complications were reported. The patients' satisfaction and return to sports were documented. The statistical analyses were preformed with Student's t-tests for independent samples. RESULTS: Fifty patients with a mean age of 52.12 years (50-64) and a mean follow-up period of 53.17 months (36-68) exhibited a mean postoperative Lysholm score of 93.7 (60-100) and IKDC score of 90.96 (57.5-100). Associated injuries occurred in 90% (45) of the patients and included the following: 76% (38) meniscal tears and 36% (18) osteochondral lesions. Complications occurred in 6% (3) of the patients and included the following: 4% (2) ACL re-ruptures and 2% (1) infections. Among all patients, 88% (44) returned to pre-injury sports levels, and 96% (48) were satisfied. CONCLUSIONS: For patients above the age of 50 years, ACL reconstruction appears to be a safe procedure with good to excellent results that are comparable to those for younger patients, and the possibility for returning to pre-injury sports levels for these patients is high.

Reconstrucción de esquina posteromedial: reporte de 30 casos / Posteromedial corner reconstruction: a report of 30 cases

OJETIVO: Reportar la experiencia, después de 1 año de seguimiento, de una serie de 30 pacientes sometidos a reconstrucción de la esquina posteromedial (EPM) con la técnica descrita por La Prade. MÉTODO: Cohorte retrospectiva de 30 pacientes con lesión de EPM operados por el mismo equipo quirúrgico. Criterios de inclusión: diagnóstico clínico, radiografía con estrés y resonancia magnética compatibles con lesión de EPM, inestabilidad grado III luego de 3 meses de tratamiento ortopédico, técnica de reconstrucción de La Prade, al menos 12 meses de seguimiento. Criterios de exclusión: discordancia entre clínica e imagenología, inestabilidad grado I o II, y otra técnica quirúrgica. Evaluación con IKDC y Lysholm antes de la cirugía, a los 6 y 12 meses de seguimiento postcirugía. RESULTADOS: 30 pacientes cumplieron los criterios de inclusión. Promedio de edad 43 años (24­69). Veintiocho pacientes presentaron lesiones de alta energía, 20 pacientes fueron diagnosticados en agudo, mientras que 10 fueron diagnosticados luego de malos resultados en reconstrucción de otros ligamentos. Veintiocho presentaron lesiones asociadas: 11 casos asociados a lesión de ligamento cruzado anterior, 3 casos asociados a lesión de ligamento cruzado posterior, 3 casos en asociación con lesiones meniscales, 9 casos con lesión asociada de ligamento cruzado anterior y posterior, y 2 casos en asociación con ligamento cruzado anterior, posterior y ligamento colateral lateral. Promedio de tiempo hasta la reconstrucción de EPM fue de 5 meses (rango 2­32). Puntuación en Lysholm e IKDC (preoperatorio 18,2 y 24,3 respectivamente), mejoraron a 76,7 y 70,7 después de 1 año de seguimiento. Al fin del seguimiento, el rango articular promedio era 113° (90­140), la mayoría de los pacientes (24) tuvieron estabilidad tipo A según IKDC. CONCLUSIÓN: La reconstrucción de lesiones de EPM mejora los resultados clínicos en pacientes con inestabilidad crónica posteromedial de rodilla. Se observó mejoría en la estabilidad y scores funcionales de todos los pacientes.

OBJETIVE: Report the experience, after 1-year follow-up, of 30 patients with La Prade's anatomical reconstruction of posteromedial corner (PMC) injuries. METHODS: Retrospective cohort study. 30 patients with PMC injuries operated by the same surgical team. Inclusion criteria: clinical presentation, stress radiographs and MRI compatible with PMC injury, grade III chronic instability in spite of at least 3 months of orthopedic treatment, La Prade's anatomical technique reconstruction, 12 months follow-up at least. Exclusion criteria: discordance between clinical and image studies, grade I or II medial instability, any other surgical technique. IKDC and Lysholm at the preoperative evaluation, 6 and 12 months after surgery. RESULTS: Thirty patients met the inclusion criteria. Mean age 43 years (24­69). 28 patients presented high-energy mechanism of injury. Twenty patients were diagnosed in the acute setting, while 10 had a delayed diagnosis after poor results of other ligament reconstruction. Majority (28) had associated injuries: 11 cases PMC + anterior cruciate ligament (ACL) injury, 3 PMC + posterior cruciate ligament (PCL) injury, 3 PMC + meniscal tears, 9 PMC + ACL + PCL injuries, and 2 PMC + ACL + PCL + lateral collateral ligament injuries. Mean time for PMC reconstruction was 5 months (range 2­32). Preoperative Lysholm and IKDC scores (18,2 and 24,3 respectively) improved to 76,7 and 70,7 after 1-year follow-up. At the end of follow-up, average ROM was 113° (90­140), most patients (24) had type A IKDC stability. CONCLUSION: Acceptable results were achieved following reconstruction of PMC injuries in patients with chronic posteromedial knee instability. We observed instability and functional scores improvement in all patients.

Torsades de pointes: a propósito de un caso clínico / Torsades of pointes: with regard to a clinical case

Analiza que la taquicardia ventricular helicoidal (torsades de pointes) y los síndromes de "QT" largo son eventos clínicos que amenazan la vida, causados por varios agentes, condiciones y defectos genéticos, relacionados con alteraciones en la repolarización ventricular que conducen a incrementar la duración del potencial de acción transmembrana, traducidos eléctricamente por una mayor duración del intervalo QT, dados por una disminución de las corrientes de salida del potasio del miocito, que generan esta arritmia por actividad desencadenada (post-despolarizaciones). Se ha analizado un caso clínico en el que se verifica la presencia de un Síndrome "QT" largo congénito, agravado por el uso prolongado de medicación anthistamínica y que desarrolla una torsades de pointes, poniendo en riesgo su vida; paciente en el que además se asocia una Pre-excitación (Wolf Parkinson White) y una Disfunción simusal y, que luego del estudio electrofisiológico es implantado un MP definitivo, amén de terapia beta-bloqueadora; en el que también se realiza investigación genética personal y familiar y que hoy se encuentra en buen estado general. Este caso ha permitido realizar una revisión del estado actual de la patología y nos ha alertado a considerar el riesgo-beneficio en la prescripción medicamentosa. La mejor prevención está en intensificar la identificación, la investigación y el reporte cuidadoso de estos hechos clínicos, lo cual conducirá a un mejor entendimiento de este raro, pero riesgoso desorden del ritmo cardíaco.

Analisis de perdidas en redes de distribucion desbalanceadas y asimetricas mediante flujos por componentes de fase

La evaluacion de las perdidas tecnicas en los sistemas de generacion y transmision, asi como en las subestaciones de distribucion no es problematica, ya que usualmente existe una medicion adecuada para este proposito. La evaluacion de las perdidas en el resto del sistema, es decir en las redes de distribucion primarias y secundarias, es por lo general mas compleja y dificultosa.