Detalhe da pesquisa
1.
Demystifying the Druggability of the MYC Family of Oncogenes.
J Am Chem Soc
; 145(6): 3259-3269, 2023 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36734615
2.
Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development.
Mol Pharm
; 19(9): 3358-3366, 2022 09 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35984034
3.
Improvements on a chemically contiguous hapten for a vaccine to address fentanyl-contaminated heroin.
Bioorg Med Chem
; 41: 116225, 2021 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34034147
4.
Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay.
Bioorg Med Chem
; 42: 116246, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34130216
5.
Enhancement of a Heroin Vaccine through Hapten Deuteration.
J Am Chem Soc
; 142(31): 13294-13298, 2020 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32700530
6.
Strategies to Counteract Botulinum Neurotoxin A: Nature's Deadliest Biomolecule.
Acc Chem Res
; 52(8): 2322-2331, 2019 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31322847
7.
Sulfonate-isosteric replacement examined within heroin-hapten vaccine design.
Bioorg Med Chem Lett
; 30(17): 127388, 2020 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32738981
8.
Chemical Interventions for the Opioid Crisis: Key Advances and Remaining Challenges.
J Am Chem Soc
; 141(5): 1798-1806, 2019 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30532973
9.
Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A.
J Am Chem Soc
; 139(21): 7264-7272, 2017 05 31.
Artigo
Inglês
| MEDLINE | ID: mdl-28475321
10.
Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG).
Bioorg Med Chem Lett
; 27(15): 3436-3440, 2017 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28600214
11.
The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response.
Org Biomol Chem
; 15(14): 2979-2992, 2017 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28294277
12.
Cocaine Vaccine Development: Evaluation of Carrier and Adjuvant Combinations That Activate Multiple Toll-Like Receptors.
Mol Pharm
; 13(11): 3884-3890, 2016 11 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27717287
13.
Studies towards the improvement of an anti-cocaine monoclonal antibody for treatment of acute overdose.
Bioorg Med Chem Lett
; 26(20): 5078-5081, 2016 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27599743
14.
Flagellin as carrier and adjuvant in cocaine vaccine development.
Mol Pharm
; 12(2): 653-62, 2015 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25531528
15.
Litomosoides sigmodontis: a jird urine metabolome study.
Bioorg Med Chem Lett
; 25(24): 5804-7, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26573416
16.
A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies.
Bioorg Med Chem Lett
; 24(19): 4664-4666, 2014 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25205191
17.
Evaluation of a hapten conjugate vaccine against the "zombie drug" xylazine.
Chem Commun (Camb)
; 60(35): 4711-4714, 2024 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38596865
18.
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
Proc Natl Acad Sci U S A
; 107(8): 3424-9, 2010 Feb 23.
Artigo
Inglês
| MEDLINE | ID: mdl-20142509
19.
Catalytic Antibody Blunts Carfentanil-Induced Respiratory Depression.
ACS Pharmacol Transl Sci
; 6(5): 802-811, 2023 May 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37200811
20.
Development of a vaccine against the synthetic opioid U-47700.
Front Pharmacol
; 14: 1219985, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37492086