Effect of cognitive behavioral therapy on pain, knee function, and psychological status in patients after primary total knee arthroplasty: a systematic review and meta-analysis.

OBJECTIVE: The clinical efficacy of cognitive behavioral therapy (CBT) after Total knee arthroplasty (TKA) is still controversial, and the purpose of this meta-analysis was to evaluate the effect of CBT on pain, knee function, and psychological status of patients after TKA. METHODS: We systematically searched electronic databases such as CNKI, CBM, VIP, PubMed, Cochrane Library, and EMBASE for randomized controlled studies up to February 30, 2023. Screening against inclusion criteria to select valid studies and extract data. The quality of included studies was evaluated by the Cochrane Collaboration risk-of-bias 2 (RoB 2) tool for randomized trials. Statistical analysis of the data from this study was carried out using Stata 15.1 software. RESULTS: Finally, our meta-analysis incorporated seven randomized controlled studies of high quality, including 608 patients. The findings of the meta-analysis demonstrated a noteworthy decrease in kinesiophobia levels during the early postoperative phase in the CBT group as compared to the usual care group (WMD = -6.35, 95% CI: -7.98 to -4.72, Z = 7.64, P < 0.001). However, no statistically significant difference between the CBT and usual care groups in terms of postoperative pain as well as knee function. CONCLUSION: CBT may effectively reduce the level of kinesiophobia in the short term after TKA, but did not significantly relieve knee pain or improve knee function.

Accuracy and reproducibility analysis of different reference axes for femoral prosthesis rotation alignment in TKA based on 3D CT femoral model.

BACKGROUND: There are many reference axes to determine the rotational positioning of the femoral prosthesis in total knee arthroplasty (TKA), mainly including the surgical transepicondylar axis (sTEA), anatomical transepicondylar axis (aTEA), Whiteside line, and the posterior condylar line (PCL), etc., but there is still no definite conclusion on which is the most accurate reference axis. OBJECTIVE: To explore the reproducibility of each reference axis of femoral external osteotomy based on the 3D CT femoral model, compare the deviation of the simulated femoral prosthesis rotation alignment, positioned based on each reference axis, with the gold standard sTEA, and analyze the accuracy of each reference axis. METHODS: The imaging data of 120 patients with knee osteoarthritis who underwent a 3D CT examination of the knee in our hospital from June 2018 to December 2021 were retrospectively collected. The 3D model of the femur was established by Mimics software. The line relative to PCL externally rotated 3° (PCL + 3°), aTEA, and the vertical line of the Whiteside line were constructed and compared with the gold standard sTEA. Intra-observer, as well as inter-observer reproducibility analysis, was performed by the intra-group correlation coefficient (ICC) and Bland-Altman method. RESULTS: The angle ∠WS, between the vertical line of Whiteside and sTEA, was 2.54 ± 2.30°, with an outlier of 54.2%; the angle ∠aTEA, between aTEA and sTEA, was 4.21 ± 1.01°, with an outlier of 99.1%; the angle ∠PCL, between PCL + 3° external rotation and sTEA, was 0.50 ± 1.06°, with the highest accuracy and an outlier of 5.8%, and the differences among all three were statistically significant, P < 0.05. The intra-observer ICC values of ∠WS, ∠aTEA, and ∠PCL were 0.975 (0.964-0.982), 0.926 (0.896-0.948), and 0.924(0.892,0.946), respectively, and the reproducibility levels were excellent; the inter-observer ICC values of ∠WS, ∠aTEA, and ∠PCL were 0.968(0.955-0.978), 0.906 (0.868-0.934) and 0.970 (0.957,0.979), respectively, with excellent reproducibility levels; Bland-Altman plots suggested that the scatter points of intra-observer and inter-observer measurement differences more than 95% were within the limits of agreement. CONCLUSION: The reference axis for locating the distal femoral external rotation osteotomy based on the 3D CT femoral model has good reproducibility. The PCL is easy to operate, has the highest precision, and the lowest outliers among the reference axes is therefore recommended.

Accuracy and reproducibility of two-dimensional computed tomography-based positioning of femoral component rotational alignment in preoperative planning for total knee arthroplasty.

BACKGROUND: Poor rotation of the femoral component in total knee arthroplasty (TKA) can result in various postoperative complications, underscoring the critical importance of preoperative planning. PURPOSE: To improve the accuracy of femoral component positioning during TKA, this study compared the accuracy and repeatability of different two-dimensional (2D) computed tomography (CT) measurement methods for measuring the posterior condylar angle (PCA) in preoperative TKA planning. METHODS: A retrospective analysis was conducted on 75 patients (150 knees) who underwent bilateral lower extremity computed tomography angiography (CTA) at Fuyang People's Hospital from January 2021 to July 2021. Three different methods were used to measure the PCA based on 2D CT images (axial CT slices) and three-dimensional(3D) models (femoral models reconstructed from CT data) in this study. Method 1: Single-plane 2D CT measurement, measuring PCA in the most obvious single-plane CT slice of the surgical transepicondylar axis (sTEA); Method 2: multi-plane 2D CT measurement, identifying and locating anatomical landmarks in multiple 2D CT slices and measuring PCA; Method 3: 3D model measurement, measuring PCA in the reconstructed femur 3D model. Compare the differences in PCA measurements between the three measurement methods. A positive PCA measurement was recorded when the sTEA was externally rotated relative to the posterior condylar line (PCL). Any difference exceeding 3° between the PCA measurement in the 2D CT and the PCA reference value in the 3D model was classified as an outlier. The intraclass correlation coefficient (ICC) and Bland-Altman method were utilized to assess the intra- and inter-observer reproducibility of the three measurement methods. RESULTS: The PCA measurement in the single-plane 2D CT was 1.91 ± 1.94°, with a measurement error of - 1.22 ± 1.32° and 12.7% of outlier values. In the multi-plane 2D CT, the PCA measurement was 2.96 ± 1.68°, with a measurement error of -0.15 ± 0.91° and 6.0% of outlier values. The PCA measurement in the 3D model was 3.12 ± 1.69°. The PCA measurement in single-plane 2D CT was notably smaller than that in multi-plane 2D CT and 3D models, with no significant difference between the latter two. The multi-plane 2D CT showed significantly lower measurement error and outlier values than the single-plane 2D CT. All three PCA measurement methods exhibited high reproducibility (ICC: 0.93 ~ 0.97). CONCLUSIONS: Using of multi-plane 2D CT for measuring PCA in preoperative planning of TKA has high reproducibility and accuracy, with fewer outlier values. We recommend preoperative measurement of PCA using muti-plane 2D CT to improve the accuracy of positioning the femoral component rotational alignment during surgery.

[Short term follow-up of unstable femoral neck fractures in young adults treated with femoral neck system and cannulated compression screws].

OBJECTIVE: To investigate the clinical efficacy of femoral neck system(FNS) and three cannulated compression screws(CCS) in the treatment of unstable femoral neck fractures in young adults. METHODS: The clinical data of 52 young and middle-aged patients with unstable femoral neck fractures admitted from August 2018 to August 2021 were reviewed and analyzed. All patients were divided into two groups according to the internal fixation method, 25 cases were treated with FNS fixation, 27 cases were treated with closed reduction and 3 CCS inverted triangular distribution. The operation time, incision length, intraoperative bleeding, hospitalization expenses and fracture reduction quality of two groups were recorded and compared;The patients were followed up regularly after operation. The fracture healing time, complete weight-bearing time and postoperative complications(nonunion, femoral neck shortening, femoral head necrosis) of two groups were compared. The Harris score was used to evaluate hip function 6 months after surgery. RESULTS: The operation was successfully completed in both groups. The patients in FNS group had more bleeding, longer incision length and higher hospitalization cost than CCS group(P<0.01). There ware no significant difference in operation time and Garden index between two groups(P>0.05). Patients in both groups were followed up for 6 to 32 months.The fracture healing time in FNS group was less than that in CCS group, the time of complete weight bearing after surgery was earlier than that in CCS group, and the hip Harris score was higher than that in CCS group (P<0.01). There were no internal fixation fracture complications in two groups during follow-up. In the FNS group, there were 4 cases of avascular necrosis of the femoral head and 2 cases of femoral neck shortening, of which 3 cases underwent total hip replacement due to avascular necrosis of the femoral head. In the CCS group, there were 2 cases of nonunion, 9 cases of avascular necrosis of the femoral head, and 11 cases of femoral neck shortening, among which 5 cases underwent total hip replacement due to nonunion and avascular necrosis of the femoral head. CONCLUSION: With simple operation, rotational stability and angular stability, FNS enables patients to start functional exercise as early as possible and reduces the incidence of postoperative complications of unstable femoral neck fracture. It is a new choice for the treatment of unstable femoral neck fracture in young adults.

The Clinical Outcomes of Measured Resection and Gap Balancing Techniques in Primary Total Knee Arthroplasty: A Meta-analysis.

BACKGROUND: At present, the clinical efficacy of measured resection (MR) and gap balancing (GB) techniques in total knee arthroplasty (TKA) is still controversial. The objective of this study was to evaluate the clinical outcome indexes of the two surgical methods through a meta-analysis. METHODS: The literature was systematically searched on PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure (CNKI), WANFANG, Weipu (VIP), and China Biomedical Literature (CBM) electronic databases inception until June 12, 2022. RevMan 5.3 software (the Nordic Cochrane Center, the Cochrane Collaboration, Copenhagen, Denmark) was used to analyze all data of this study. The Cochrane risk bias assessment tool is a risk bias evaluation criterion recommended by the Cochrane Handbook for systematic reviews. RESULTS: Eleven studies involving 1268 knees in total were included. The main outcome indexes showed that the Knee Society Score (KSS) knee score (MD: -1.40; 95% CI: -2.57 to -0.22; p = 0.02) and KSS knee function score (MD: -3.11; 95% CI: -3.72 to -2.50; p < 0.001) in the GB group were higher 1 year after operation, while femoral component rotation angle (FCRA; MD: -0.75; 95% CI: -1.34 to -0.07; p = 0.03) and the osteotomy volume of the posterior medial femoral condyle (MD: -0.76; 95% CI; -1.13 to -0.38; p < 0.001) were greater in the GB group. In addition, there was no significant difference in the joint line change (MD: -0.03; 95% CI: -0.07 to 0.01; p = 0.16) between the two groups. Secondary outcome results showed that the knee joint range of motion (ROM) in 3 months, and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) score after 1 year were better in the GB group. However, the operation time of the MR group was shorter. In addition, this study revealed no significant differences in post-complications between these two groups. CONCLUSION: Although the GB technique may not provide better radiographic results or reduce the complication rate, the recovery of joint function showed earlier improvement.

[Effect of vascularized peroneus longus tendon graft reconstruction on anterior cruciate ligament insertion in rabbits].

OBJECTIVE: To investigate the effect of vascularized peroneus longus tendon graft reconstruction on anterior cruciate ligament (ACL) insertion in rabbits. METHODS: Eighty healthy New Zealand white rabbits were harvested to prepare ACL injury models and randomly divided into two groups ( n=40). The ACL was reconstructed with vascularized peroneus longus tendon graft in group A and peroneus longus tendon graft without blood supply in group B. The survival of animals and the healing of incision were observed after operation; the grafts were taken for gross and histological observations at 4, 8, and 16 weeks; the biomechanical test of the grafts was carried out to record the maximum tensile strength and incidence of ACL insertion rupture at 8 and 16 weeks. RESULTS: All animals survived until the experiment completed. General observation showed that the tunnel was combined with grafts, the vascular infiltration was abundant, and no obvious boundary between the tunnel and grafts existed at 16 weeks in group A; there was still an obvious boundary between the tunnel and graft in group B. Histological observation showed that the collagen fibers between tendon and bone in group A increased gradually, the dense fiber connection was formed, and the "tidal-line" like structure similar to the normal ACL insertion was formed at 16 weeks; but the"tidal-line" like structure was not obvious in group B. Biomechanical test showed that there was no significant difference in the incidence of ACL insertion rupture at 8 and 16 weeks between group A and group B ( P=0.680; P=0.590), but the maximum tensile strength at 8 and 16 weeks were higher in group A than in group B ( t=18.503, P=0.001; t=25.391, P=0.001). CONCLUSION: The vascularized peroneus longus tendon graft for ACL reconstruction can obviously promote the outcome of the ACL insertion.