Detalhe da pesquisa
1.
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.
J Biol Chem
; 299(12): 105475, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37981208
2.
Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease.
Brain Behav Immun
; 109: 251-268, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36682515
3.
Hepatocyte expression of the micropeptide adropin regulates the liver fasting response and is enhanced by caloric restriction.
J Biol Chem
; 295(40): 13753-13768, 2020 10 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32727846
4.
Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury.
J Neuroinflammation
; 17(1): 339, 2020 Nov 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33183330
5.
Risk of incident dementia following metformin initiation compared with noninitiation or delay of antidiabetic medication therapy.
Pharmacoepidemiol Drug Saf
; 29(6): 623-634, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32363681
6.
Association Between Metformin Initiation and Incident Dementia Among African American and White Veterans Health Administration Patients.
Ann Fam Med
; 17(4): 352-362, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31285213
7.
Behavioral characterization of G-protein-coupled receptor 160 knockout mice.
Pain
; 165(6): 1361-1371, 2024 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38198232
8.
Biochemical, biomarker, and behavioral characterization of the GrnR493X mouse model of frontotemporal dementia.
bioRxiv
; 2024 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37398305
9.
Biochemical, Biomarker, and Behavioral Characterization of the GrnR493X Mouse Model of Frontotemporal Dementia.
Mol Neurobiol
; 2024 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38696065
10.
The senescence accelerated mouse (SAMP8) as a model for oxidative stress and Alzheimer's disease.
Biochim Biophys Acta
; 1822(5): 650-6, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22142563
11.
Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice.
Proc Natl Acad Sci U S A
; 107(51): 22272-7, 2010 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-21135231
12.
Aging, Plasminogen Activator Inhibitor 1, Brain Cell Senescence, and Alzheimer's Disease.
Aging Dis
; 14(2): 515-528, 2023 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37008063
13.
Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn R493X mouse model of frontotemporal dementia.
PLoS One
; 18(3): e0282822, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36893203
14.
A DUAL MTOR/NAD+ ACTING GEROTHERAPY.
bioRxiv
; 2023 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36711589
15.
Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment.
J Clin Invest
; 132(17)2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36047496
16.
Targeting the A3 adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice.
Acta Neuropathol Commun
; 10(1): 11, 2022 01 29.
Artigo
Inglês
| MEDLINE | ID: mdl-35093182
17.
Adropin transgenesis improves recognition memory in diet-induced obese LDLR-deficient C57BL/6J mice.
Peptides
; 146: 170678, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34695512
18.
Neurovascular protection by adropin in experimental ischemic stroke through an endothelial nitric oxide synthase-dependent mechanism.
Redox Biol
; 48: 102197, 2021 Nov 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34826783
19.
Synthesis and structure-activity relationships of 3,4,5-trisubstituted-1,2,4-triazoles: high affinity and selective somatostatin receptor-4 agonists for Alzheimer's disease treatment.
RSC Med Chem
; 12(8): 1352-1365, 2021 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34458738
20.
Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice.
NPJ Aging Mech Dis
; 7(1): 23, 2021 Aug 30.
Artigo
Inglês
| MEDLINE | ID: mdl-34462439