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1.
BMC Public Health ; 18(Suppl 4): 1306, 2018 Dec 13.
Artigo em Inglês | MEDLINE | ID: mdl-30541514

RESUMO

BACKGROUND: The year 2014 was a turning point for polio eradication in Nigeria. Confronted with the challenges of increased numbers of polio cases detected in rural, hard-to-reach (HTR), and security-compromised areas of northern Nigeria, the Nigeria polio program introduced the HTR project in four northern states to provide immunization and maternal and child health services in these communities. The project was set up to improve population immunity, increase oral polio vaccine (OPV) and other immunization uptake, and to support Nigeria's efforts to interrupt polio transmission by 2015. Furthermore, the project also aimed to create demand for these services which were often unavailable in the HTR areas. To this end, the program developed a community engagement (CE) strategy to create awareness about the services being provided by the project. The term HTR is operationally defined as geographically difficult terrain, with any of the following criteria: having inter-ward/inter-Local Government Area/interstate borders, scattered households, nomadic population, or waterlogged/riverine area, with no easy to access to healthcare facilities and insecurity. METHODS: We evaluated the outcome of CE activities in Kano, Bauchi, Borno, and Yobe states to examine the methods and processes that helped to increase OPV and third pentavalent (penta3) immunization coverage in areas of implementation. We also assessed the number of community engagers who mobilized caregivers to vaccination posts and the service satisfaction for the performance of the community engagers. RESULTS: Penta3 coverage was at 22% in the first quarter of project implementation and increased to 62% by the fourth quarter of project implementation. OPV coverage also increased from 54% in the first quarter to 76% in the last quarter of the 1-year project implementation. CONCLUSIONS: The systematic implementation of a CE strategy that focused on planning and working with community structures and community engagers in immunization activities assisted in increasing OPV and penta3 immunization coverage.


Assuntos
Participação da Comunidade , Programas de Imunização/organização & administração , Imunização/estatística & dados numéricos , Unidades Móveis de Saúde , Criança , Vacina contra Difteria, Tétano e Coqueluche/administração & dosagem , Vacinas Anti-Haemophilus/administração & dosagem , Humanos , Nigéria , Vacina Antipólio de Vírus Inativado/administração & dosagem , Vacina Antipólio Oral/administração & dosagem , Avaliação de Programas e Projetos de Saúde , Vacinas Combinadas/administração & dosagem
2.
Anesth Analg ; 121(5): 1301-5, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26218861

RESUMO

BACKGROUND: In a retrospective survey, we found 1% cases with complete and partial failure of spinal anesthesia for cesarean delivery between 2008 and 2010, which we attributed to underreporting because of the study design. In this prospective study, we determined the incidence of failed spinal anesthesia and identified the factors that increased its risk. METHODS: This prospective, observational study consisted of all spinal anesthetics administered for cesarean delivery surgery from January 2011 to December 2013. Our definition of failure covered complete (preoperative) failure to achieve a pain-free operative condition and pain during surgery (intraoperative failure). RESULTS: Of a total of 3568 cesarean deliveries, there were 3239 (90.8%) spinal blocks, and the overall failure was 294 (9.1%). These were rescued by conversion to general anesthesia (22.8%) and repeating spinal (23.1%) and IV analgesic supplementation (54.1%). Analysis by logistic regression model indicated that factors associated with failure were the level of experience of the anesthesia provider as shown by senior registrar (adjusted risk ratio [RR], 1.4; 95% confidence interval [CI], 1.0-1.9), >1 lumbar puncture attempt (adjusted RR, 1.5; 95% CI, 1.1-1.9), and use of the L4/L5 interspace (adjusted RR, 1.7; 95% CI, 1.4-2.0). CONCLUSIONS: The rate of failed spinal anesthesia from this study was high. The independent predictors of failure were multiple lumbar puncture attempts, use of the L4/L5 interspace, and the level of experience of the anesthesia provider. It is imperative to develop clear guidelines to standardize our obstetric spinal anesthetic practice as well as the management of failures.


Assuntos
Anestesia Obstétrica/métodos , Raquianestesia/métodos , Hospitais de Ensino/métodos , Dor do Parto/tratamento farmacológico , Dor do Parto/epidemiologia , Adulto , Anestesia Obstétrica/normas , Raquianestesia/normas , Feminino , Hospitais de Ensino/normas , Humanos , Incidência , Dor do Parto/diagnóstico , Nigéria/epidemiologia , Gravidez , Estudos Prospectivos , Estudos Retrospectivos , Fatores de Risco , Falha de Tratamento
3.
BMC Infect Dis ; 14: 344, 2014 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-24950705

RESUMO

BACKGROUND: Lassa fever is highly contagious and commonly results in death. It is therefore necessary to diagnose and report any suspected case of Lassa fever to facilitate preventive strategies. This study assessed the preparedness of physicians in the diagnosis and reporting of Lassa fever. METHODS: The study design was descriptive cross-sectional. The consenting medical doctors completed a self-administered questionnaire on the diagnosis and reporting of Lassa fever. Descriptive and inferential statistics were used in data analyses. RESULTS: One hundred seventy-five physicians participated in the study. The mean age was 41.5 ± 10.9 years (range, 24-75 years). Most of the physicians were male (78.9%) and had practiced medicine ≥ 20 years (51.5%). Most of the physicians had a good knowledge regarding the diagnosis and reporting of Lassa fever; however, none of the physicians had ever diagnosed or reported a suspected case. Predictors of good knowledge include male sex, not practicing at a secondary health care level and post graduation year more than 20 years. CONCLUSION: There is disparity in knowledge and practices of physicians regarding the diagnosis and reporting of Lassa fever. Thus, it is necessary to improve the knowledge and practices of physicians regarding the diagnosis and reporting of Lassa fever.


Assuntos
Febre Lassa/diagnóstico , Médicos , Adulto , Estudos Transversais , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Febre Lassa/terapia , Masculino , Pessoa de Meia-Idade , Nigéria , Inquéritos e Questionários
4.
Artigo em Inglês | MEDLINE | ID: mdl-21521808

RESUMO

We assessed the waiting time and perceived satisfaction with care among people living with HIV/AIDS (PLHIV) at an antiretroviral clinic in Nigeria. A structured questionnaire was administered during interviews. Four hundred patients completed the questionnaire. The mean age of the respondents was 36.4 years (SD 9.7 years), and 61% of them were females. A majority, 72.9%, reported that the time elapsed between entry into the clinic and access to medical care services (waiting time) was more than an hour. However, a majority (77%) expressed satisfaction with the medical care they received. Although the majority of PLHIV were satisfied with their medical care, more needs to be done to reduce patient waiting time before access to medical services.


Assuntos
Instituições de Assistência Ambulatorial/normas , Satisfação do Paciente , Síndrome da Imunodeficiência Adquirida/tratamento farmacológico , Adolescente , Adulto , Fármacos Anti-HIV/uso terapêutico , Estudos Transversais , Feminino , Ambiente de Instituições de Saúde , Nível de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Nigéria , Inquéritos e Questionários , Fatores de Tempo , Adulto Jovem
5.
Pan Afr Med J ; 43: 176, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36879638

RESUMO

Introduction: continued transmission of Lassa fever has been recorded in 6 Local Government Areas (LGAs) of Ondo State in Southwest, Nigeria annually with high case fatality rates. Genomic analysis of the Lassa virus has indicated ongoing transmission from local rodents´ population to humans despite several public health interventions during the outbreak including risk communication on preventive practices against the disease. We assessed adherence to preventive practices by household against the spread of Lassa fever in these affected LGAs. Methods: a descriptive cross-sectional study was conducted among community members in the six affected Local Government Area (LGAs). A semi structured questionnaire was administered to 2992 consenting respondents to assess their reported preventive practice against Lassa fever while their observed practices was assessed using observation checklist. Data analysis was done using frequency, proportions, Chi-Square test and logistic regression of predictors of outcome variable with statistical significance set at p<0.05. Results: a higher proportion of the respondents were females (51.2%) compared to males (48.8%) with mean age of 43.04±13.97 years. Majority of the respondents (88.2%) were married with at least secondary education (76.7%). Majority of the respondents (80.2%) reported washing their hands with soap and water regularly, 84.6% washed their utensils before and after use likewise. However, 10.6% of the respondents reported not storing their food items in lid-covered containers while 61.9% practiced open air drying of food items by the roadside. Also, 34.3% of the respondents were observed to spread food items outside their home in the open air. Overall, 32.6% of the respondent were observed to have poor preventive practices against Lassa fever with their level of education as a significant determinant. Conclusion: the poor preventive practices observed among the respondents in this study could sustain the transmission of the virus hence there is also the need to further intensify enforcement of public health control measures for Lassa fever through existing community structures and institutions to stop the current and prevent future Lassa fever and other related outbreaks in the State.


Assuntos
Febre Lassa , Feminino , Masculino , Humanos , Adulto , Pessoa de Meia-Idade , Febre Lassa/epidemiologia , Febre Lassa/prevenção & controle , Estudos Transversais , Nigéria , Surtos de Doenças/prevenção & controle , Saúde Pública
6.
BMJ Open ; 11(8): e048694, 2021 08 09.
Artigo em Inglês | MEDLINE | ID: mdl-34373306

RESUMO

OBJECTIVE: This study employed the Consolidated Framework for Implementation Research (CFIR) to assess factors that enhanced or impeded the implementation of community engagement strategies using the Nigerian polio programme as a point of reference. DESIGN: This study was a part of a larger descriptive cross-sectional survey. The CFIR was used to design the instrument which was administered through face-to-face and phone interviews as well as a web-based data collection platform, Qualtrics. SETTING: The study took place in at least one State from each of the six geopolitical zones in Nigeria (Nasarawa, Borno, Kano, Sokoto, Anambra, Bayelsa, Lagos, Ondo and Oyo States as well as the Federal Capital Territory). PARTICIPANTS: The respondents included programme managers, policy-makers, researchers and frontline field implementers affiliated with the Global Polio Eradication Initiative (PEI) core partner organisations, the three tiers of the government health parastatals (local, state and federal levels) and academic/research institutions. RESULTS: Data for this study were obtained from 364 respondents who reported participation in community engagement activities in Nigeria's PEI. Majority (68.4%) had less than 10 years' experience in PEI, 57.4% were involved at the local government level and 46.9% were team supervisors. Almost half (45.0%) of the participants identified the process of conducting the PEI program and social environment (56.0%) as the most important internal and external contributor to implementing community engagement activities in the community, respectively. The economic environment (35.7%) was the most frequently reported challenge among the external challenges to implementing community engagement activities. CONCLUSION: Community engagement strategies were largely affected by the factors relating to the process of conducting the polio programme, the economic environment and the social context. Therefore, community engagement implementers should focus on these key areas and channel resources to reduce obstacles to achieve community engagement goals.


Assuntos
Erradicação de Doenças , Poliomielite , Participação da Comunidade , Estudos Transversais , Humanos , Nigéria , Poliomielite/epidemiologia , Poliomielite/prevenção & controle
7.
PLoS One ; 16(8): e0252798, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34449777

RESUMO

BACKGROUND: Despite efforts to improve childhood immunization coverage in Nigeria, coverage has remained below the national acceptable level. In December 2019, we conducted an assessment of Missed Opportunities for Vaccination (MOV) in Ondo State, in Southwest Nigeria. The objectives were to determine the magnitude of, explore the reasons for, as well as possible solutions for reducing MOV in the State. METHODS: This was a cross-sectional study using a mixed-methods approach. We purposively selected 66 health facilities in three local government authorities, with a non-probabilistic sampling of caregivers of children 0-23 months for exit interviews, and health workers for knowledge, attitudes, and practices (KAP) surveys. Data collection was complemented with focus group discussions and in-depth interviews with caregivers and health workers. The proportion of MOV among children with documented vaccination histories were determined and thematic analysis of the qualitative data was carried out. RESULTS: 984 caregivers with children aged 0-23 months were interviewed, of which 869 were eligible for inclusion in our analysis. The prevalence of MOV was 32.8%. MOV occurred among 90.8% of children during non-vaccination visits, and 7.3% during vaccination visits. Vaccine doses recommended later in the immunization series were given in a less timely manner. Among 41.0% of health workers, they reported their vaccination knowledge was insufficient. Additionally, 57.5% were concerned about and feared adverse events following immunization. Caregivers were found to have a low awareness about vaccination, and issues related to the organization of the health system were found to contribute towards MOV. CONCLUSIONS: One in three children experienced a MOV during a health service encounter. Potential interventions to reduce MOV include training of health workers about immunization policies and practices, improving caregivers' engagement and screening of vaccination documentation by health workers during every health service encounter.


Assuntos
Cuidadores , Instalações de Saúde , Conhecimentos, Atitudes e Prática em Saúde , Pessoal de Saúde , Programas de Imunização , Vacinação , Estudos Transversais , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Nigéria
8.
Anesth Analg ; 110(1): 243-4, 2010 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-19933532

RESUMO

There is growing interest in the use of regional anesthesia worldwide. With this survey, we determined the use of regional techniques among anesthesiologists in Nigeria using a cross-sectional study design. A self-administered questionnaire was mailed to a randomly generated list of anesthesiologists in Nigeria. From 196 questionnaires, 140 anesthesiologists (71.4%) responded. Regular use of spinal, epidural, and peripheral nerve blocks was 92.9%, 15%, and 2.9%, respectively. A high percentage of respondents (47.1%) had never performed a nerve block and only 31.4% had used a nerve stimulator technique. Limited exposure to equipment and techniques accounted for their lack of use.


Assuntos
Anestesia por Condução/estatística & dados numéricos , Anestesiologia/estatística & dados numéricos , Estudos Transversais , Estimulação Elétrica , Pesquisas sobre Atenção à Saúde , Humanos , Bloqueio Nervoso , Nigéria/epidemiologia , Nervos Periféricos , Inquéritos e Questionários
9.
Paediatr Anaesth ; 20(11): 1036-9, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-20964770

RESUMO

BACKGROUND: Spinal anesthesia is underutilized for surgery in children in Nigeria. Until recently, only caudal and general anesthesia are employed in the pediatric age group, and the thought of spinal anesthesia was an anathema. This study evaluated cardiovascular changes, duration of spinal block, the length of surgery, length of spinal needle to establish lumbar puncture, and the incidence of complications associated with this procedure. METHODS: Thirty-two children ASA 1 and 2 between the ages of 2 and 12 had spinal block from August 1, 2008 to February 28, 2010 for orthopedic and plastic surgical procedures. Spinal block was carried out at L5/S1 interspace, and the dose of bupivacaine was 0.5 mg·kg(-1). RESULT: Satisfactory surgical anesthesia was achieved in 31 of 32 children. There was no sensory or motor block within 10 min in one child, despite an easy lumbar puncture necessitating the use of general anesthesia. No patient showed oxygen desaturation, bradycardia, or hypotension. Two (6.5%) children aged 5 and 8 reported mild, position-dependent headaches, 3 (9.7%) had nausea and vomiting, and 5 (16.1%) had postspinal shivering. There was a positive correlation between the size of the child and the needle length to establish spinal anesthesia (r = 0.7, P = 0.0001). CONCLUSION: This study demonstrates that spinal anesthesia in children causes minimal hemodynamic disruption and therefore is a safe technique for lower extremity surgeries. This technique that hitherto has not been popular with children in our environment has been found to be safe and equally effective.


Assuntos
Raquianestesia , Raquianestesia/efeitos adversos , Raquianestesia/métodos , Anestésicos Locais/administração & dosagem , Peso Corporal , Bupivacaína/administração & dosagem , Criança , Pré-Escolar , Feminino , Hemodinâmica/fisiologia , Humanos , Complicações Intraoperatórias/epidemiologia , Extremidade Inferior/cirurgia , Masculino , Agulhas , Bloqueio Nervoso , Procedimentos Ortopédicos , Complicações Pós-Operatórias/epidemiologia , Náusea e Vômito Pós-Operatórios/epidemiologia , Estudos Prospectivos , Estremecimento , Punção Espinal
10.
Artigo em Inglês | MEDLINE | ID: mdl-20357035

RESUMO

HIV infection from occupational and nonoccupational exposures can be prevented through risk assessment and management with antiretroviral drug therapy (ART). This study sought to examine the pattern of presentation and outcome of clients who were given postexposure prophylaxis (PEP) at the University College Hospital, Ibadan, Nigeria. A retrospective review of case notes of clients presenting for HIV PEP from January 2005 to December 2006 was carried out. A total of 48 clients with a mean age of 27.9 +/- 12.3 years underwent PEP during the period under review. Rape constituted 50% of reasons for PEP, while needle pricks and blood splash into mucous membranes constituted 25% each. Among those who received therapy, 10 (23.8%) could not complete drug therapy because of side effects. Although no client was HIV positive after the recommended 6 months of follow-up, 8 (16.7%) clients did not complete attendance to the clinic during the period.


Assuntos
Terapia Antirretroviral de Alta Atividade , Infecções por HIV/prevenção & controle , Profilaxia Pós-Exposição , Adolescente , Adulto , Patógenos Transmitidos pelo Sangue , Criança , Pré-Escolar , Feminino , Humanos , Transmissão de Doença Infecciosa do Paciente para o Profissional/prevenção & controle , Masculino , Pessoa de Meia-Idade , Ferimentos Penetrantes Produzidos por Agulha/epidemiologia , Nigéria/epidemiologia , Estupro/estatística & dados numéricos , Estudos Retrospectivos
11.
Niger Postgrad Med J ; 17(2): 138-46, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20539330

RESUMO

OBJECTIVES: To assess knowledge, attitude and management practices on intimate partner violence (IPV) in primary care practice and determine barriers to screening, safety concerns and prior training of health workers. METHODS: Self administered questionnaire interview of 298 health workers from 104 health facilities in the 33 local government areas of Oyo state. RESULTS: Health workers underestimated IPV, 80% estimated that less than 10% of women in their practice experience violence. Only 35% (105) screened routinely for IPV, while 43% (129) had ever identified a victim. Response of health workers when they found oppressed women were often (64.5%) limited to treatment of injuries. Many (66.1%) believed it was an intrusion into patient's private life to inquire about violence. Ninety per cent (270) expressed concern for their personal safety if they were to discuss with the oppressed or perpetrators. Many (74.8%) believed that they could assist men who perpetrate violence, while 92.3% believed they could assist abused women. Only 18.8% (56) had ever received training on violence. Health workers with previous training on IPV were three times more likely to screen (AOR 2.66; 95%CI: 1.52-4.63), while the more senior cadre were more likely (AOR 1.62; 95% CI: 1.13-2.81) to have identified an oppressed woman. Although not significant, females had better knowledge and attitudes than men (OR 0.67; 0.96-2.94 and 0.78; 0.44-1.40). CONCLUSIONS: Health workers were willing to discuss IPV, but lacked fundamental knowledge on IPV. Training efforts that focus on screening and comprehensive management are urgently required.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Programas de Rastreamento , Maus-Tratos Conjugais/diagnóstico , Violência , Adulto , Atitude do Pessoal de Saúde , Feminino , Humanos , Relações Interpessoais , Masculino , Pessoa de Meia-Idade , Nigéria , Médicos , Atenção Primária à Saúde , Parceiros Sexuais , Maus-Tratos Conjugais/psicologia , Adulto Jovem
12.
Pan Afr Med J ; 37: 6, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32983324

RESUMO

A vaccine-derived poliovirus (VDPV) was isolated in an acute flaccid paralysis (AFP) case reported from Ile-Ife, in Osun state, Southwest Nigeria. We investigated the epidemiological characteristics of the polio event and described the immediate public health response that followed. We interviewed the primary caregiver of the case and conducted active case searches for additional AFP cases in the communities in Ife East Local Government Area (LGA) of Osun state. Stool samples of contacts and non-contacts were collected and sent for laboratory investigation. A public health response with mass supplementary immunization in the affected areas followed immediately in the ward the case was located in October 2015. Also, we reviewed the administrative record of the oral polio vaccine (OPV) coverage in the LGA in the previous four years. The VDPV case was a female, one-month-old child with adequate vaccination history for her age. However, the environment of the child was relatively filthy with inappropriate facilities. Laboratory reports from contact samples were negative for VDPV or any polio isolates. A missed AFP case was found from active case searches and a high proportion of under-five children was immunized with tOPV. The OPV3 administrative coverage in the LGA peaked in 2014 (103%) and dropped in 2015 (67%). Efforts directed toward improving environmental hygiene in households and improving OPV coverage in subsequent routine and supplementary immunization are suggested.


Assuntos
Viroses do Sistema Nervoso Central/diagnóstico , Mielite/diagnóstico , Doenças Neuromusculares/diagnóstico , Poliomielite/prevenção & controle , Vacina Antipólio Oral/administração & dosagem , Poliovirus/isolamento & purificação , Viroses do Sistema Nervoso Central/virologia , Pré-Escolar , Surtos de Doenças , Feminino , Humanos , Lactente , Masculino , Vacinação em Massa/métodos , Mielite/virologia , Doenças Neuromusculares/virologia , Nigéria , Saúde Pública , Vacinação/estatística & dados numéricos
13.
Health Policy ; 89(1): 72-7, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18573565

RESUMO

OBJECTIVE: To carry out a comparative cost-effectiveness analysis of screening methods for urinary schistosomiasis; terminal haematuria, unqualified haematuria, dysuria, visual urine examination and chemical reagent strip technique, in a school-based control programme. DESIGN: Estimation of costs and determination of cost-effect ratios of the screening methods applied in a school-based screening and treatment programme, from the perspective of a programme manager. SETTING: A junior secondary school in Ibadan, Nigeria. MAIN OUTCOME MEASURES: Cost per number of cases correctly diagnosed. RESULTS: Unqualified haematuria was found to be the most cost-effective method costing N51.06 (US$ 2.16) to diagnose a case correctly, followed by terminal haematuria N58.91 (US$ 2.50) and dysuria N84.24 (US$ 3.57). Despite the relatively high input costs of chemical reagent strip technique over visual urine examination (N22.12 (US$ 0.94) per student vs. N6.44 (US$ 0.27) per student), it was found to be more cost effective costing N304.56 (US$ 12.91) to diagnose a case correctly than visual examination of urine cost of N317.58 (US$ 13.46) per correct case diagnosed. CONCLUSION: From the viewpoint of a programme manager, interview method of screening by asking for blood in the urine remains the most efficient means of screening for urinary schistosomiasis in school-based control programmes in our environment.


Assuntos
Análise Custo-Benefício , Programas de Rastreamento/economia , Esquistossomose Urinária/diagnóstico , Instituições Acadêmicas , Programas de Rastreamento/métodos , Nigéria , Esquistossomose Urinária/prevenção & controle
14.
Artigo em Inglês | MEDLINE | ID: mdl-19357425

RESUMO

OBJECTIVE: To assess the awareness and attitude of antiretroviral clinic workers to HIV/AIDS and highly active antiretroviral therapy (HAART). METHODS: A descriptive cross-sectional study design using a self-administered questionnaire was used. RESULTS: Of the 43 staff, 39 (92.5%) completed the questionnaire. Their mean age was 35.1 + 7.6 years. There were 19 (48.7%) males and 20 (51.7%) females. The majority (87.2%) had tertiary education. More than three fifths (61.5%) were married. There were 20 (51.3%) professional staff and 19 (48.7%) support staff. Only 28.2% of staff members had ever received on-the-job training in HIV/AIDS care. None of the adherence counselors had ever received any training in HIV/AIDS care and HAART adherence counseling. Despite this lack of training, this majority of the clinic staff had good knowledge about and a positive attitude to HIV/AIDS and HAART adherence. CONCLUSION: Adherence counselors and support staff required on-the-job training for optimum job performance.


Assuntos
Terapia Antirretroviral de Alta Atividade/psicologia , Atitude do Pessoal de Saúde , Competência Clínica , Infecções por HIV/psicologia , Síndrome da Imunodeficiência Adquirida/tratamento farmacológico , Síndrome da Imunodeficiência Adquirida/psicologia , Adulto , Competência Clínica/estatística & dados numéricos , Estudos Transversais , Feminino , Infecções por HIV/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Nigéria , Cooperação do Paciente , Inquéritos e Questionários , Adulto Jovem
15.
Ann Afr Med ; 8(2): 100-4, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19805940

RESUMO

OBJECTIVE: To assess treatment outcomes and determinants of outcome among tuberculosis patients. DESIGN: A longitudinal study design involving a cohort of sputum smear-positive pulmonary tuberculosis patients at initiation of therapy, who were followed up to the end of treatment at eighth month. SETTING: Tuberculosis treatment centers in Ibadan, Nigeria. RESULTS: A total of 1,254 patients were followed up with a mean age of 35.0+/-3.3 years. The percentages of patients with treatment outcomes assessed in the study were as follows: cure (76.6%), failure (8.1%), default (6.6%), transferred out (4.8%), and death (1.9%). The cure rate varied significantly between treatment centers from 40 to 94.4% (P<0.05). The treatment centers located within the specialist health centers at Jericho and the University College Hospital had 50 and 75% cure rates, respectively.The mean age of cured patients was 31.2+/3.1 years which was significantly lower than the mean age of those with poor treatment outcomes (36.7+/3.5 years; P<0.05). Males had a higher risk of a poor treatment outcome (RR=1.8; 95% CI: 1.02-1.94) than females. Also, patients with a poor knowledge of tuberculosis had a higher risk of having a poor treatment outcome (RR=1.35; 95% CI: 1.25-1.62) compared to those with knowledge. CONCLUSION: Variations in health center treatment outcomes and poor knowledge of tuberculosis among patients suggest that poor program implementation quality may be a major modifiable determinant of treatment outcomes in our environment.


Assuntos
Tuberculose Pulmonar/terapia , Adolescente , Adulto , Feminino , Hospitais de Doenças Crônicas , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Nigéria/epidemiologia , Risco , Medição de Risco , Escarro/química , Resultado do Tratamento , Tuberculose Pulmonar/epidemiologia , Adulto Jovem
16.
PLoS One ; 13(11): e0206086, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30395617

RESUMO

Vaccine preventable diseases (VPDs) are a leading course of child under-five mortality in sub-Saharan Africa. A target of 95% immunization coverage is necessary for the sustained control of VPDs. This study aims to determine the immunization status and its associated demo-graphic factors among children 12-59 months old in Akinyele Local Government area (LGA), Oyo State, Nigeria. A community-based cross-sectional study was carried out in one urban and one rural ward of Akinyele LGA. Fourhundred and forty-four (449) Under-five children were selected by multistage sampling technique. Data were collected from caregivers using interviewer administered questionnaires. Odds ratios at 95% CIand Chi square at 5% significant level were computed to identify the factors associated with non or partial immunisation. Multiple logistics regression at 5% significance level was done to determine the socio-demographic determinants of immunisation status. Overall, 449 children aged 12-59 months were surveyed of which 213(47.4%) were males and 236(52.6%) were from urban area. Overall, 365(81.3%) was fully immunized, 75(16.7%) was partially immunized and 9(2.0%) had never been immunized. Predictors of a child being partially or un-immunised were being in the fourth wealth quintile (AOR 7.9; 95%CI: 2.7-18.0), poorest wealth quintile (AOR 14.5; 95%CI 4.2-20.5), having a mother with no education (AOR 6.4; 95%CI: 2.9-14.1) and a mother that practiced Islam (AOR: 2.2; 95%CI: 1.3-3.7). Immunisation coverage was somewhat high but still suboptimal among the study population. Strategies that improve female literacy and those that target religious institutions may be effective in improving immunisation uptake.


Assuntos
Demografia/estatística & dados numéricos , Imunização/estatística & dados numéricos , População Rural/estatística & dados numéricos , População Urbana/estatística & dados numéricos , Adulto , Antígenos/imunologia , Criança , Humanos , Lactente , Governo Local , Nigéria
17.
PLoS Curr ; 102018 Jun 29.
Artigo em Inglês | MEDLINE | ID: mdl-30094105

RESUMO

INTRODUCTION: An outbreak of Lassa Fever (LF) reported and confirmed in Ondo state, Southwest Nigeria in January 2016 was investigated. This paper provides the epidemiology of the LF and lessons learnt from the investigation of the outbreak. METHODS: The incidence management system (IMS) model was used for the outbreak coordination. Cases and deaths were identified through the routine surveillance system using standard definitions for suspected and confirmed cases and deaths respectively. Blood specimens collected from suspect cases were sent for confirmation at a WHO accredited laboratory. Active case search was intensified, and identified contacts of confirmed cases were followed up for the maximum incubation period of the disease. Other public health responses included infection prevention and control, communication and advocacy as well as case management. Data collected were analysed using SPSS 20, by time, place and persons and important lessons drawn were discussed.   Results: We identified 90 suspected LF cases of which 19 were confirmed by the laboratory. More than half (52.6%) of the confirmed cases were females with majority (73.7%) in the age group ≥ 15 years. The Case Fatality Rate (CFR) of 63.2% among the laboratory-confirmed positive cases where 9 of 19 cases died, was significantly higher compared to the laboratory confirmed negative cases where 6 of the 65 cases died ( CFR; 8.5%) p ≤ 0.05. Two hundred and eighty-seven contacts of the confirmed cases were identified, out of which 267(93.0%) completed  the follow-up without developing any symptoms and 2 (0.7%) developed symptoms consistent with LF and were confirmed by the laboratory. More than half of the contacts were females (64.5%) with most of them (89.2%) in the age group ≥ 25 years.   Discussion: One key lesson learnt from the investigation was that the confirmed cases were mainly primary cases; hence the needs to focus on measures of breaking the chain of transmission in the animal-man interphase during Lassa fever epidemic preparedness and response. In addition, the high case fatality rate despite early reporting and investigation suggested the need for a review of the case management policy and structure in the State. Key Words: Lassa fever, Outbreak Response, Incident Management System, Nigeria.

18.
Niger Med J ; 58(1): 1-6, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29238121

RESUMO

Epidemic prone diseases threaten public health security. These include diseases such as cholera, meningitis, and hemorrhagic fevers, especially Lassa fever for which Nigeria reports considerable morbidity and mortality annually. Interestingly, where emergency epidemic preparedness plans are in place, timely detection of outbreaks is followed by a prompt and appropriate response. Furthermore, due to the nature of spread of Lassa fever in an outbreak setting, there is the need for health-care workers to be familiar with the emerging epidemic management framework that has worked in other settings for effective preparedness and response. This paper, therefore, discussed the principles of epidemic management using an emergency operating center model, review the epidemiology of Lassa fever in Nigeria, and provide guidance on what is expected to be done in preparing for epidemic of the disease at the health facilities, local and state government levels in line with the Integrated Disease Surveillance and Response strategy.

19.
Local Reg Anesth ; 9: 83-86, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27785098

RESUMO

We describe the use of single-shot lamina thoracic paravertebral block (TPVB) with sedation for a 56-year-old female patient who had modified radical mastectomy with axillary clearance. Two years ago, she suffered vocal cord palsy post thyroidectomy, which was managed with tracheostomy. The tracheostomy tube was removed 8 months later, leaving the patient with persistent hoarseness of voice and left vocal cord palsy. She declined general anesthesia and consented for TPVB. The surgery lasted 95 minutes and was successfully completed with TPVB. Her vital signs were stable during the operation. She had low pain scores, minimal opioid use, early alimentation, and no postoperative nausea and vomiting and was discharged early. We present the anesthetic management of this case in our setting, where TPVB under ultrasound guidance and modern drug-delivery systems for sedation are unavailable.

20.
Int J Infect Dis ; 43: 62-67, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26724773

RESUMO

OBJECTIVES: Despite the availability of vaccines, children are the people most often affected by epidemic meningococcal meningitis. The pattern of the epidemic meningococcal meningitis outbreak in Northern Nigeria in 2009 and the Neisseria meningitidis strains responsible for this epidemic are described here. METHODS: A retrospective cross-sectional study was conducted in 16 states, involving 48 local government areas (LGAs), 91 health facilities, and 96 communities. Data collection involved in-depth interviews with key informants from the federal to the community level, a review of records, and a solution-oriented national workshop with participants from all states of the Federation. Cerebrospinal fluid (CSF) samples were collected from some of the suspected cases at the start of the outbreak and were tested using the rapid Pastorex latex agglutination kit. RESULTS: Kastina (11153, 20.4%), Jigawa (8643, 15.8%), Bauchi (8463, 15.5%), Kano (6811, 12.4%), and Gombe (6110, 11.2%) were the states with the highest prevalence of meningitis. The states of Nasarawa (11.0%), Adamawa (8.0%), and Borno (7.6%) recorded the highest percentage of deaths, while the Shongom (Gombe State 12.5%), Illela (Sokoto State 9.8%), and Ikara (Kaduna State 9.1%) LGAs recorded the most deaths amongst cases seen. CONCLUSIONS: The testing of CSF samples during meningitis outbreaks is recommended in order to monitor the occurrence of the multiple meningitis serotypes during these outbreaks and to direct serotype-specific vaccination response activities.


Assuntos
Surtos de Doenças , Epidemias , Meningite Meningocócica/epidemiologia , Vacinas Meningocócicas/administração & dosagem , Neisseria meningitidis/imunologia , Vacinação , Testes de Aglutinação , Estudos Transversais , Humanos , Meningite Meningocócica/mortalidade , Neisseria meningitidis/isolamento & purificação , Nigéria/epidemiologia , Estudos Retrospectivos , Risco , Sorogrupo
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