Detalhe da pesquisa
1.
Pharmacologic Approach to Sinoatrial Node Dysfunction.
Annu Rev Pharmacol Toxicol
; 61: 757-778, 2021 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33017571
2.
Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacemaker compartments heterogeneity: A computer model analysis.
PLoS Comput Biol
; 19(12): e1011708, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38109436
3.
Fibroblast-Specific Proteotranscriptomes Reveal Distinct Fibrotic Signatures of Human Sinoatrial Node in Nonfailing and Failing Hearts.
Circulation
; 144(2): 126-143, 2021 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33874740
4.
Comprehensive evaluation of electrophysiological and 3D structural features of human atrial myocardium with insights on atrial fibrillation maintenance mechanisms.
J Mol Cell Cardiol
; 151: 56-71, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33130148
5.
In silico investigation of the mechanisms underlying atrial fibrillation due to impaired Pitx2.
PLoS Comput Biol
; 16(2): e1007678, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32097431
6.
Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels.
Philos Trans A Math Phys Eng Sci
; 378(2173): 20190557, 2020 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32448059
7.
Increased cross-bridge recruitment contributes to transient increase in force generation beyond maximal capacity in human myocardium.
J Mol Cell Cardiol
; 114: 116-123, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29141185
8.
Etiology-dependent impairment of relaxation kinetics in right ventricular end-stage failing human myocardium.
J Mol Cell Cardiol
; 121: 81-93, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29981798
9.
SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Proc Natl Acad Sci U S A
; 112(40): 12528-33, 2015 Oct 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26392562
10.
Adenosine-Induced Atrial Fibrillation: Localized Reentrant Drivers in Lateral Right Atria due to Heterogeneous Expression of Adenosine A1 Receptors and GIRK4 Subunits in the Human Heart.
Circulation
; 134(6): 486-98, 2016 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27462069
11.
Eleven-year trends of inpatient pacemaker implantation in patients diagnosed with sick sinus syndrome.
J Cardiovasc Electrophysiol
; 28(8): 933-943, 2017 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-28471545
12.
Insights into length-dependent regulation of cardiac cross-bridge cycling kinetics in human myocardium.
Arch Biochem Biophys
; 601: 48-55, 2016 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26854725
13.
Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.
Proc Natl Acad Sci U S A
; 110(25): 10312-7, 2013 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23733959
14.
Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.
Eur Heart J
; 36(11): 686-97, 2015 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-24216388
15.
Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts.
Eur Heart J
; 36(35): 2390-401, 2015 Sep 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26059724
16.
Alternating membrane potential/calcium interplay underlies repetitive focal activity in a genetic model of calcium-dependent atrial arrhythmias.
J Physiol
; 593(6): 1443-58, 2015 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25384790
17.
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Circulation
; 130(4): 315-24, 2014 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24838362
18.
The Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium.
Am J Physiol Heart Circ Physiol
; 309(12): H2077-86, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26453335
19.
Optimization of catheter ablation of atrial fibrillation: insights gained from clinically-derived computer models.
Int J Mol Sci
; 16(5): 10834-54, 2015 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25984605
20.
Conduction remodeling in human end-stage nonischemic left ventricular cardiomyopathy.
Circulation
; 125(15): 1835-47, 2012 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22412072