Hybrid sensor based on a hollow square core fiber for temperature independent refractive index detection.

In this work, a hybrid sensor based on a section of hollow square core fiber (HSCF) spliced between two single mode fibers is proposed for the measurement of refractive index of liquids. The sensor, with a length of a few millimeters, operates in a transmission configuration. Due to the HSCF inner geometry, two different interferometers are generated. The first, a Mach-Zehnder interferometer, is insensitive to the external refractive index, and presents a sensitivity to temperature of (29.2 ± 1.1) pm/°C. The second one, a cladding modal interferometer, is highly sensitive to the external refractive index. An experimental resolution of 1.0 × 10-4 was achieved for this component. Due to the different responses of each interferometer to the parameters under study, a compensation method was developed to attain refractive index measurements that are temperature independent. The proposed sensor can find applications in areas where refractive index measurements are required and the control of room temperature is a challenge, such as in the food and beverage industry, as well as in biochemical or biomedical industries.

Simultaneous measurement of displacement and temperature using a balloon-like hybrid fiber sensor.

A fiber sensor based on a silica capillary in a balloon-like shape for simultaneous measurement of displacement and temperature is proposed and experimentally demonstrated. The sensor is fabricated by splicing a segment of a hollow-core fiber between two single-mode fibers (SMF) and by creating a balloon shape with the capillary at the top-center position. The SMF-capillary-SMF configuration excites an antiresonant (AR) guidance, and the balloon shape enhances the Mach-Zehnder interferometer (MZI). Experimental results show that, for a balloon length of 4.0 cm and a capillary length of 1.2 cm, the AR is insensitive to displacement and its sensitivity to temperature is 14.3 pm/°C, while the MZI has a sensitivity to displacement of 1.68 nm/mm in the range between 0 and 5 mm and a sensitivity to temperature of 28.6 pm/°C, twice the value of the AR. The proposed fiber sensor has only one sensing element in one configuration, which makes it simple to fabricate as well as low cost.

Optical Fiber Sensor for Monitoring the Evaporation of Ethanol-Water Mixtures.

An inline optical fiber sensor is proposed to monitor in real time the evaporation process of ethanol-water binary mixtures. The sensor presents two interferometers, a cladding modal interferometer (CMI) and a Mach-Zehnder interferometer (MZI). The CMI is used to acquire the variations in the external medium refractive index, presenting a maximum sensitivity of 387 nm/RIU, and to attain the variation in the sample concentration profile, while the MZI monitors temperature fluctuations. For comparison purposes, an image analysis is also conducted to obtain the droplet profile. The sensor proposed in this work is a promising alternative in applications where a rigorous measurement of volatile organic compound concentrations is required, and in the study of chemical and physical properties related to the evaporation process.

Real-Time Measurement of Refractive Index Using 3D-Printed Optofluidic Fiber Sensor.

This work describes a 3D-printed optofluidic fiber sensor to measure refractive index in real time, combining a microfluidic system with an optical fiber extrinsic Fabry-Perot interferometer. The microfluidic chip platform was developed for this purpose through 3D printing. The Fabry-Perot cavity was incorporated in the microfluidic chip perpendicularly to the sample flow, which was of approximately 3.7 µL/s. The optofluidic fiber sensor platform coupled with a low-cost optical power meter detector was characterized using different concentrations of glucose solutions. In the linear regression analysis, the optical power shift was correlated with the refractive index and a sensitivity of -86.6 dB/RIU (r2 = 0.996) was obtained. Good results were obtained in terms of stability with a maximum standard deviation of 0.03 dB and a sensor resolution of 5.2 × 10-4 RIU. The feasibility of the optofluidic fiber sensor for dynamic analyses of refractive index with low sample usage was confirmed through real-time measurements.

Sensitive skin: Active ingredients on the spotlight.

OBJECTIVE: Sensitive skin is characterized by self-reported sensory perceptions in response to stimuli that should not provoke unpleasant sensations. Cosmetic products for sensitive skin are designed to minimize these symptoms. This study aimed to unveil the most used active ingredients for sensitive skin in facial care products from the pharmacy and parapharmacy channel. METHODS: A pool of products from the pharmacy and parapharmacy channel whose label included the expressions 'sensitive skin', 'reactive skin' or 'intolerant skin' were analysed. The active ingredients were identified from product compositions and ranked in descending order of occurrence. The scientific evidence regarding the mechanism of action and efficacy of each ingredient was also compiled. RESULTS: Eighty-eight products from 19 multinational brands were included. Niacinamide leads the top, followed by Avena sativa, allantoin, glycyrrhetinic acid and derivatives and Laminaria ochroleuca. Ingredients that can reduce skin inflammation and act on the skin barrier were used in more than half of the products analysed. The clinical studies regarding the active ingredients used in these products remain sparse and lack methodological quality. Among the top ingredients, niacinamide, panthenol and acetyl dipeptide-1 cetyl ester were the only ones studied on volunteers having sensitive skin, while acetyl dipeptide-1 cetyl ester and palmitoyl tripeptide-8 were designed to act on the molecular targets involved in this condition. CONCLUSION: This study reveals the most used active ingredients in cosmetic products for sensitive skin, as well as the scientific evidence supporting their efficacy and the mechanisms of action. This insight is meaningful for dermatologists and other health professionals to provide customized advice based on the symptomatology of individuals with sensitive skin, and for the formulation of cosmetic products and design of new active ingredients.

OBJECTIF: La peau sensible se caractérise par des perceptions sensorielles autorapportées en réponse à des stimuli qui ne devraient pas provoquer de sensations désagréables. Les produits cosmétiques pour peaux sensibles sont conçus pour minimiser ces symptômes. Cette étude visait à dévoiler les principes actifs les plus utilisés pour les peaux sensibles dans les produits de soins du visage de la pharmacie et de la chaîne de parapharmacie. MÉTHODES: Un ensemble de produits de la chaîne pharmacie et parapharmacie, dont l'étiquette comportait les expressions « peau sensible ¼, « peau réactive ¼ ou « peau intolérante ¼ ont été analysés. Les principes actifs ont été identifiés à partir des compositions du produit et classés par ordre décroissant d'occurrence. Les preuves scientifiques concernant le mécanisme d'action et l'efficacité de chaque ingrédient ont également été compilées. RÉSULTATS: Quatre-vingt-huit produits provenant de 19 marques multinationales ont été inclus. Le niacinamide est en tête, suivi de l'Avena sativa, de l'allantoïne, de l'acide glycyrrhétinique et de ses dérivés et de Laminaria ochroleuca. Des ingrédients pouvant réduire l'inflammation cutanée et agir sur la barrière cutanée ont été utilisés dans plus de la moitié des produits analysés. Les études cliniques concernant les principes actifs utilisés dans ces produits restent rares et manquent de qualité méthodologique. Parmi les principaux ingrédients, le niacinamide, le panthénol et l'ester de dipeptide acétyl-1 ont été les seuls étudiés sur des volontaires ayant une peau sensible, tandis que l'ester de dipeptide acétyl-1 et le tripeptide palmitoyl-8 ont été conçus pour agir sur les cibles moléculaires qui interviennent dans cette affection. CONCLUSION: Cette étude révèle les principes actifs les plus utilisés dans les produits cosmétiques pour les peaux sensibles, ainsi que les preuves scientifiques étayant leur efficacité et les mécanismes d'action. Cet éclairage est important pour les dermatologues et autres professionnels de la santé pour apporter des conseils personnalisés basés sur la symptomatologie des personnes ayant la peau sensible, et pour la formulation de produits cosmétiques et la conception de nouveaux principes actifs.

Negative curvature hollow core fiber sensor for the measurement of strain and temperature.

Three different types of strain and temperature sensors based on negative curvature hollow core fiber (NCHCF) are proposed. Each sensor is produced by splicing a small section of the NCHCF between two sections of single mode fiber. Different types of interferometers are obtained simply by changing the splicing conditions. The first sensor consists on a single Fabry-Perot interferometer (FPI). The remaining two configurations are attained with the same sensing structure, depending on its position in relation to the interrogation setup. Thus, a double FPI or a hybrid sensor, the latter being composed by an FPI and a Michelson interferometer, are formed. The inline sensors are of submillimeter size, thus enabling nearly punctual measurements.

Double Antiresonance Fiber Sensor for the Simultaneous Measurement of Curvature and Temperature.

Antiresonant hollow core fibers (ARHCFs) have gained some attention due to their notoriously attractive characteristics on managing optical properties. In this work, an inline optical fiber sensor based on a hollow square core fiber (HSCF) is proposed. The sensor presents double antiresonance (AR), namely an internal AR and an external AR. The sensor was designed in a transmission configuration, where the sensing head was spliced between two single mode fibers (SMFs). A simulation was carried out to predict the behaviors of both resonances, and revealed a good agreement with the experimental observations and the theoretical model. The HSCF sensor presented curvature sensitivities of -0.22 nm/m-1 and -0.90 nm/m-1, in a curvature range of 0 m-1 to 1.87 m-1, and temperature sensitivities of 21.7 pm/°C and 16.6 pm/°C, in a temperature range of 50 °C to 500 °C, regarding the external resonance and internal resonance, respectively. The proposed sensor is promising for the implementation of several applications where simultaneous measurement of curvature and temperature are required.

Optical Harmonic Vernier Effect: A New Tool for High Performance Interferometric Fibre Sensors.

The optical Vernier effect magnifies the sensing capabilities of an interferometer, allowing for unprecedented sensitivities and resolutions to be achieved. Just like a caliper uses two different scales to achieve higher resolution measurements, the optical Vernier effect is based on the overlap in the responses of two interferometers with slightly detuned interference signals. Here, we present a novel approach in detail, which introduces optical harmonics to the Vernier effect through Fabry-Perot interferometers, where the two interferometers can have very different frequencies in the interferometric pattern. We demonstrate not only a considerable enhancement compared to current methods, but also better control of the sensitivity magnification factor, which scales up with the order of the harmonics, allowing us to surpass the limits of the conventional Vernier effect as used today. In addition, this novel concept opens also new ways of dimensioning the sensing structures, together with improved fabrication tolerances.

Fabry-Perot cavity based on silica tube for strain sensing at high temperatures.

In this work, a Fabry-Perot cavity based on a new silica tube design is proposed. The tube presents a cladding with a thickness of ~14 µm and a hollow core. The presence of four small rods, of ~20 µm diameter each, placed in diametrically opposite positions ensure the mechanical stability of the tube. The cavity, formed by splicing a section of the silica tube between two sections of single mode fiber, is characterized in strain and temperature (from room temperature to 900 °C). When the sensor is exposed to high temperatures, there is a change in the response to strain. The influence of the thermal annealing is investigated in order to improve the sensing head performance.

Silica microspheres array strain sensor.

An optical fiber sensor based on arrays of silica microspheres is proposed. The microspheres are produced separately using a fusion splicer and then also connected in series by fusion splicing. Three different sensors are presented, differing by the number of microspheres. Due to the geometry of the structures, different behaviors are obtained in strain measurements. Sensors with an odd number of microspheres are more sensitive to strain than the ones with an even number of microspheres. Additionally, the sensing heads are subjected to temperature where a sensitivity of 20.3 pm/°C is obtained in a range of 200°C.

How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies.

Skin repair encompasses epidermal barrier repair and wound healing which involves multiple cellular and molecular stages. Therefore, many skin repair strategies have been proposed. In order to characterize the usage frequency of skin repair ingredients in cosmetics, medicines, and medical devices, commercialized in Portuguese pharmacies and parapharmacies, a comprehensive analysis of the products' composition was performed. A total of 120 cosmetic products, collected from national pharmacies online platforms, 21 topical medicines, and 46 medical devices, collected from INFARMED database, were included in the study, revealing the top 10 most used skin repair ingredients in these categories. A critical review regarding the effectiveness of the top ingredients was performed and an in-depth analysis focused on the top three skin repair ingredients pursued. Results demonstrated that top three most used cosmetic ingredients were metal salts and oxides (78.3%), vitamin E and its derivatives (54.2%), and Centella asiatica (L.) Urb. extract and actives (35.8%). Regarding medicines, metal salts and oxides were also the most used (47.4%) followed by vitamin B5 and derivatives (23.8%), and vitamin A and derivatives (26.3%). Silicones and derivatives were the most common skin repair ingredients in medical devices (33%), followed by petrolatum and derivatives (22%) and alginate (15%). This work provides an overview of the most used skin repair ingredients, highlighting their different mechanisms of action, aiming to provide an up-to-date tool to support health professionals' decisions.

Towards the control of highly sensitive Fabry-Pérot strain sensor based on hollow-core ring photonic crystal fiber.

A high sensitivity Fabry-Pérot (FP) strain sensor based on hollow-core ring photonic crystal fiber was investigated. A low-finesse FP cavity was fabricated by splicing a section of hollow-core ring photonic crystal fiber between two standard single mode fibers. The geometry presents a low cross section area of silica enabling to achieve high strain sensitivity. Strain measurements were performed by considering the FP cavity length in a range of 1000 µm. The total length of the strain gauge at which strain was applied was also studied for a range of 900 mm. The FP cavity length variation highly influenced the strain sensitivity, and for a length of 13 µm a sensitivity of 15.4 pm/µÎµ was attained. Relatively to the strain gauge length, its dependence to strain sensitivity is low. Finally, the FP cavity presented residual temperature sensitivity (~0.81 pm/°C).

Spatial optical filter sensor based on hollow-core silica tube.

A spatial optical filter based on a hollow-core silica tube is proposed. Because of the hollow-core dimensions, it is possible to obtain a periodical spatial filter ranging from 1200 to 1700 nm with a channel spacing of 2.64 THz. The bandwidth is approximately 5.32 nm, and the isolation loss is ~30 dB. The optical losses are approximately ~0.67 dB/mm for a wavelength of 1500 nm. The 40 mm long spatial optical filter is tested as a sensing element and subjected to different physical parameters. The spatial optical filter is wavelength sensitive to strain and temperature, while for refractive-index variations there is an optical power dependency. This fiber structure can be used as a sensing element for extreme conditions, such as in very high temperature environments, where it presents a sensitivity of 27.5 pm °C(-1).

Fabry-Perot cavity based on a diaphragm-free hollow-core silica tube.

A Fabry-Perot (FP) cavity of simple design and based on a pure silica diaphragm-free hollow tube is proposed. Its operation is based on a first reflection of light at the end of the single-mode fiber that illuminates the silica rod and in a second reflection that takes place at the end of the rod. The FP cavity is characterized for high temperature, pressure and refractive index sensing, showing useful characteristics for the measurement of these three parameters. The diaphragm-free configuration simplifies the measurement of the refractive index of fluids.