Detalhe da pesquisa
1.
Incipient functional SARS-CoV-2 diversification identified through neural network haplotype maps.
Proc Natl Acad Sci U S A
; 121(10): e2317851121, 2024 Mar 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38416684
2.
Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
PLoS Pathog
; 19(5): e1011373, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37126532
3.
Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of Ribavirin.
Antimicrob Agents Chemother
; 67(1): e0131522, 2023 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36602354
4.
Amino Acid Substitutions Associated with Treatment Failure for Hepatitis C Virus Infection.
J Clin Microbiol
; 58(12)2020 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32999010
5.
Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc Natl Acad Sci U S A
; 114(27): E5343-E5351, 2017 07 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28634303
6.
Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J Virol
; 92(20)2018 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30068642
7.
Viral RNA-Dependent RNA Polymerases: A Structural Overview.
Subcell Biochem
; 88: 39-71, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29900492
8.
(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules
; 24(13)2019 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31247979
9.
Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J Virol
; 90(15): 6864-6883, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27194768
10.
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
PLoS Pathog
; 11(3): e1004733, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25799064
11.
Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J Virol
; 89(13): 6848-59, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25903341
12.
Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc Natl Acad Sci U S A
; 110(51): 20503-8, 2013 Dec 17.
Artigo
Inglês
| MEDLINE | ID: mdl-24302762
13.
The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site.
J Virol
; 88(10): 5595-607, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24600002
14.
Synergism between remdesivir and ribavirin leads to SARS-CoV-2 extinction in cell culture.
Br J Pharmacol
; 2024 Apr 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38616133
15.
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
PLoS Pathog
; 6(8): e1001072, 2010 Aug 26.
Artigo
Inglês
| MEDLINE | ID: mdl-20865120
16.
Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc Natl Acad Sci U S A
; 106(16): 6603-7, 2009 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-19346474
17.
SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations.
Pathogens
; 11(6)2022 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35745516
18.
SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes.
Microbiol Spectr
; 10(2): e0022122, 2022 04 27.
Artigo
Inglês
| MEDLINE | ID: mdl-35348367
19.
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin.
J Virol
; 84(12): 6188-99, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20392853
20.
Coupled sterol synthesis and transport machineries at ER-endocytic contact sites.
J Cell Biol
; 220(10)2021 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34283201