Detalhe da pesquisa
1.
Circadian rhythms govern cardiac repolarization and arrhythmogenesis.
Nature
; 483(7387): 96-9, 2012 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-22367544
2.
Ionic bases for electrical remodeling of the canine cardiac ventricle.
Am J Physiol Heart Circ Physiol
; 305(3): H410-9, 2013 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23709598
3.
Molecular determinants of pentamidine-induced hERG trafficking inhibition.
Mol Pharmacol
; 81(2): 198-209, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22046004
4.
Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.
J Biol Chem
; 286(39): 34413-25, 2011 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-21832094
5.
Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.
J Biol Chem
; 286(45): 39091-9, 2011 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-21908602
6.
Oxidative inactivation of the lipid phosphatase phosphatase and tensin homolog on chromosome ten (PTEN) as a novel mechanism of acquired long QT syndrome.
J Biol Chem
; 286(4): 2843-52, 2011 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21097842
7.
Phosphoinositide binding differentially regulates NHE1 Na+/H+ exchanger-dependent proximal tubule cell survival.
J Biol Chem
; 286(49): 42435-42445, 2011 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22020933
8.
Gap junction heterogeneity as mechanism for electrophysiologically distinct properties across the ventricular wall.
Am J Physiol Heart Circ Physiol
; 298(3): H787-94, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20035026
9.
Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum.
Mol Pharmacol
; 75(4): 927-37, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19139152
10.
Hypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS.
Biochem Biophys Res Commun
; 388(2): 212-6, 2009 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-19654002
11.
Mitochondrial reactive oxygen species mediate hypoxic down-regulation of hERG channel protein.
Biochem Biophys Res Commun
; 373(2): 309-14, 2008 Aug 22.
Artigo
Inglês
| MEDLINE | ID: mdl-18570888
12.
Doxazosin induces apoptosis of cells expressing hERG K+ channels.
Eur J Pharmacol
; 579(1-3): 98-103, 2008 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-18054910
13.
Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity.
J Clin Invest
; 128(3): 1043-1056, 2018 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29431731
14.
KChIP2 is a core transcriptional regulator of cardiac excitability.
Elife
; 62017 03 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28263709
15.
Voltage-gated sodium channels assemble and gate as dimers.
Nat Commun
; 8(1): 2077, 2017 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29233994
16.
Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.
Circ Res
; 92(12): e87-100, 2003 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-12775586
17.
HERG channel trafficking.
Novartis Found Symp
; 266: 57-69; discussion 70-4, 95-9, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-16050262
18.
HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk.
J Pharmacol Toxicol Methods
; 52(1): 136-45, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-15950494
19.
Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X).
Cardiovasc Res
; 64(3): 467-76, 2004 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15537500
20.
The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.
Br J Pharmacol
; 137(6): 892-900, 2002 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-12411421