Detalhe da pesquisa
1.
Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.
Cell
; 179(4): 984-1002.e36, 2019 10 31.
Artigo
Inglês
| MEDLINE | ID: mdl-31675503
2.
Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization.
Circulation
; 145(16): 1205-1217, 2022 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35300523
3.
Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases.
Hum Mol Genet
; 29(8): 1388-1395, 2020 05 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32219344
4.
Adiposity and grip strength: a Mendelian randomisation study in UK Biobank.
BMC Med
; 20(1): 201, 2022 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35650572
5.
Lipid lowering and Alzheimer disease risk: A mendelian randomization study.
Ann Neurol
; 87(1): 30-39, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31714636
6.
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
BMC Cardiovasc Disord
; 19(1): 240, 2019 10 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31664920
7.
Obesity causes cardiovascular diseases: adding to the weight of evidence.
Eur Heart J
; 41(2): 227-230, 2020 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31504435
8.
Mendelian randomization of blood lipids for coronary heart disease.
Eur Heart J
; 36(9): 539-50, 2015 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24474739
9.
HLA class II locus and susceptibility to podoconiosis.
N Engl J Med
; 366(13): 1200-8, 2012 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-22455414
10.
Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population.
Pharmacogenomics J
; 15(1): 101-108, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25069476
11.
Prioritising genetic findings for drug target identification and validation.
Atherosclerosis
; 390: 117462, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38325120
12.
Cardiac MRI to guide heart failure and atrial fibrillation drug discovery: a Mendelian randomization analysis.
Res Sq
; 2023 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36778476
13.
Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders.
medRxiv
; 2023 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37645746
14.
Exploring the Role of Plasma Lipids and Statin Interventions on Multiple Sclerosis Risk and Severity: A Mendelian Randomization Study.
Neurology
; 101(17): e1729-e1740, 2023 10 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37657941
15.
Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog.
BMJ Med
; 2(1): e000554, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37859783
16.
Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes.
Commun Med (Lond)
; 3(1): 9, 2023 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36670186
17.
Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity.
Sci Adv
; 9(17): eadd4984, 2023 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37126556
18.
Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.
Nat Genet
; 55(6): 964-972, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37248441
19.
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.
Nat Genet
; 55(10): 1651-1664, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37770635
20.
Homofermentative production of D-lactic acid from sucrose by a metabolically engineered Escherichia coli.
Biotechnol Lett
; 34(11): 2069-75, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22791225