Detalhe da pesquisa
1.
BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors.
Mol Cancer
; 22(1): 110, 2023 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37443114
2.
Challenges and Opportunities in Cancer Drug Resistance.
Chem Rev
; 121(6): 3297-3351, 2021 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32692162
3.
Simplification, not "tropicalization", of temperate marine ecosystems under ocean warming and acidification.
Glob Chang Biol
; 27(19): 4771-4784, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34268836
4.
Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.
PLoS Pathog
; 9(3): e1003234, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23555249
5.
Overcoming osimertinib resistance with AKT inhibition in EGFRm-driven Non-Small-Cell-Lung-Cancer with PIK3CA/PTEN alterations.
Clin Cancer Res
; 2024 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38630555
6.
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J Med Chem
; 2024 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38770784
7.
Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors.
J Hepatol
; 57(5): 1021-8, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22750466
8.
Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells.
Cancer Res Commun
; 2(10): 1312-1325, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36969743
9.
Anti-PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC.
JCI Insight
; 7(3)2022 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35132961
10.
The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells.
NPJ Precis Oncol
; 6(1): 95, 2022 Dec 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36575215
11.
Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance.
J Med Chem
; 64(18): 13704-13718, 2021 09 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34491761
12.
Cell shape and TGF-beta signaling define the choice of lineage during in vitro differentiation of mouse primary hepatic precursors.
J Cell Physiol
; 225(1): 186-95, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20458741
13.
Osimertinib, an Irreversible Next-Generation EGFR Tyrosine Kinase Inhibitor, Exerts Antitumor Activity in Various Preclinical NSCLC Models Harboring the Uncommon EGFR Mutations G719X or L861Q or S768I.
Mol Cancer Ther
; 19(11): 2298-2307, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32943544
14.
Modeling Dose and Schedule Effects of AZD2811 Nanoparticles Targeting Aurora B Kinase for Treatment of Diffuse Large B-cell Lymphoma.
Mol Cancer Ther
; 18(5): 909-919, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30872381
15.
Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors.
Cancer Res
; 78(12): 3267-3279, 2018 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29555874
16.
Optimizing the design of population-based patient-derived tumor xenograft studies to better predict clinical response.
Dis Model Mech
; 11(11)2018 10 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30254068
17.
Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions.
Mol Cancer Ther
; 17(5): 885-896, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29483211
18.
Optimizing Therapeutic Effect of Aurora B Inhibition in Acute Myeloid Leukemia with AZD2811 Nanoparticles.
Mol Cancer Ther
; 16(6): 1031-1040, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28292940
19.
Modulation of oxidative stress by twist oncoproteins.
PLoS One
; 8(8): e72490, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23967308
20.
Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.
Cancer Res
; 72(17): 4483-93, 2012 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22815528