Detalhe da pesquisa
1.
The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond-Blackfan anemia by targeting Nemo-like kinase.
J Biol Chem
; 297(3): 100988, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34298020
2.
Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector.
Haematologica
; 107(2): 446-456, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33440921
3.
Prospective isolation of radiation induced erythroid stress progenitors reveals unique transcriptomic and epigenetic signatures enabling increased erythroid output.
Haematologica
; 105(11): 2561-2571, 2020 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33131245
4.
The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis-Therapeutic Opportunities in Hemolytic Conditions.
Int J Mol Sci
; 21(19)2020 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33008134
5.
Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing.
J Cell Physiol
; 234(9): 16503-16516, 2019 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-30793301
6.
ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.
Nature
; 499(7456): 92-6, 2013 Jul 04.
Artigo
Inglês
| MEDLINE | ID: mdl-23748442
7.
Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation.
Genes Dev
; 25(24): 2573-8, 2011 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22155924
8.
miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.
Genes Dev
; 25(2): 119-24, 2011 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21196494
9.
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia.
Mol Ther
; 25(8): 1805-1814, 2017 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28434866
10.
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
Br J Haematol
; 171(4): 517-29, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26305041
11.
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
Blood
; 120(11): 2225-8, 2012 Sep 13.
Artigo
Inglês
| MEDLINE | ID: mdl-22791294
12.
Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia.
Haematologica
; 99(12): 1792-8, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25216681
13.
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications.
Blood
; 118(24): 6258-68, 2011 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-21998215
14.
HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal.
Blood
; 117(12): 3435-44, 2011 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-21177435
15.
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
Blood
; 118(23): 6087-96, 2011 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21989989
16.
Recombinant α1-Microglobulin (rA1M) Protects against Hematopoietic and Renal Toxicity, Alone and in Combination with Amino Acids, in a 177Lu-DOTATATE Mouse Radiation Model.
Biomolecules
; 13(6)2023 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37371508
17.
Progress towards mechanism-based treatment for Diamond-Blackfan anemia.
ScientificWorldJournal
; 2012: 184362, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22619618
18.
Small Molecules Pushing Erythroid/Megakaryocyte Cell Specification Boundaries.
Cell Reprogram
; 24(5): 225-227, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36219716
19.
Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia.
Exp Hematol
; 105: 50-61, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34757171
20.
Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway.
Cell Rep
; 41(5): 111571, 2022 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36323262