Detalhe da pesquisa
1.
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
; 182(5): 1252-1270.e34, 2020 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32818467
2.
Therapeutic drug monitoring of osimertinib in non-small cell lung cancer and short bowel syndrome: A case report.
Br J Clin Pharmacol
; 90(1): 344-349, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37815301
3.
Time course of CYP3A activity during and after metamizole (dipyrone) in healthy volunteers.
Br J Clin Pharmacol
; 89(8): 2458-2464, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36946257
4.
Effect of Clarithromycin, a Strong CYP3A and P-glycoprotein Inhibitor, on the Pharmacokinetics of Edoxaban in Healthy Volunteers and the Evaluation of the Drug Interaction with Other Oral Factor Xa Inhibitors by a Microdose Cocktail Approach.
Cardiovasc Drugs Ther
; 2023 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36870039
5.
Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers.
Eur J Clin Pharmacol
; 78(12): 1965-1972, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36258053
6.
Treatment with Edoxaban Attenuates Acute Stroke Severity in Mice by Reducing Blood-Brain Barrier Damage and Inflammation.
Int J Mol Sci
; 22(18)2021 Sep 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34576055
7.
Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug-drug interactions with different perpetrator drugs.
Br J Clin Pharmacol
; 86(8): 1632-1641, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32159869
8.
Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers.
Br J Clin Pharmacol
; 85(7): 1528-1537, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30912163
9.
Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC-MS/MS-Based Assay.
Anal Chem
; 90(15): 9395-9402, 2018 08 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29985592
10.
Rivaroxaban and macitentan can be coadministered without dose adjustment but the combination of rivaroxaban and St John's wort should be avoided.
Br J Clin Pharmacol
; 84(12): 2903-2913, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30192025
11.
Given the Data of Hommers and Colleagues, Valproic Acid Is Not an Unequivocal Inducer of Clozapine Metabolism.
J Clin Psychopharmacol
; 39(4): 419-420, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31188239
12.
No alteration of voriconazole concentration by plasmapheresis in a critically ill patient.
Eur J Clin Pharmacol
; 75(2): 287-288, 2019 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-30349944
13.
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers.
Clin Pharmacokinet
; 63(4): 469-481, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38393578
14.
CYP3A and CYP2C19 Activity Determined by Microdosed Probe Drugs Accurately Predict Voriconazole Clearance in Healthy Adults.
Clin Pharmacokinet
; 62(9): 1305-1314, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37505445
15.
Frailty as a Marker for the Plasma Concentrations of Direct Oral Anticoagulants in Older Patients: Results of an Exploratory Study.
Drugs Aging
; 40(2): 153-164, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36637788
16.
The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Neuro Oncol
; 25(3): 566-579, 2023 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35882450
17.
Oral Drugs Against COVID-19.
Dtsch Arztebl Int
; 119(15): 263-269, 2022 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35302484
18.
Effect of Pantoprazole on the Absorption of Hydroxychloroquinea A Randomized Drug-Drug Interaction Trial in Healthy Adults.
Clin Pharmacol Drug Dev
; 11(2): 285-290, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34268908
19.
Low Exposure to Direct Oral Anticoagulants Is Associated with Ischemic Stroke and Its Severity.
J Stroke
; 24(1): 88-97, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-35135063
20.
Simultaneous Quantification and Pharmacokinetic Characterization of Doxapram and 2-Ketodoxapram in Porcine Plasma and Brain Tissue.
Pharmaceutics
; 14(4)2022 Mar 31.
Artigo
Inglês
| MEDLINE | ID: mdl-35456597