Detalhe da pesquisa
1.
Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore.
Cell
; 179(3): 736-749.e15, 2019 10 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31626772
2.
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity.
J Transl Med
; 21(1): 690, 2023 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37840136
3.
Applications of Genome Editing Technologies in CAD Research and Therapy with a Focus on Atherosclerosis.
Int J Mol Sci
; 24(18)2023 Sep 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37762360
4.
Genetic Admixture in the Culturally Unique Peranakan Chinese Population in Southeast Asia.
Mol Biol Evol
; 38(10): 4463-4474, 2021 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34152401
5.
Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype.
Circ Res
; 127(6): 761-777, 2020 08 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32529949
6.
Cardiac epigenetics: Driving signals to the cardiac epigenome in development and disease.
J Mol Cell Cardiol
; 151: 88, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33232681
7.
Hypertrophic signaling compensates for contractile and metabolic consequences of DNA methyltransferase 3A loss in human cardiomyocytes.
J Mol Cell Cardiol
; 154: 115-123, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33582159
8.
An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility.
Circulation
; 142(16): 1562-1578, 2020 10 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32885664
9.
Prioritizing Candidates of Post-Myocardial Infarction Heart Failure Using Plasma Proteomics and Single-Cell Transcriptomics.
Circulation
; 142(15): 1408-1421, 2020 10 13.
Artigo
Inglês
| MEDLINE | ID: mdl-32885678
10.
Transposable elements that have recently been mobile in the human genome.
BMC Genomics
; 22(1): 789, 2021 Nov 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34732136
11.
Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy.
Mol Ther
; 28(6): 1506-1517, 2020 06 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32304667
12.
Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling.
Circulation
; 137(23): 2497-2513, 2018 06 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29371215
13.
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
J Mol Cell Cardiol
; 120: 53-63, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29792884
14.
Erbin is a negative modulator of cardiac hypertrophy.
Proc Natl Acad Sci U S A
; 111(16): 5902-7, 2014 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24711380
15.
Alternative Hypothesis to Explain Disease Progression in Rheumatic Heart Disease.
Circulation
; 142(22): 2091-2094, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33253001
16.
Assigning Distal Genomic Enhancers to Cardiac Disease-Causing Genes.
Circulation
; 142(9): 910-912, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32866060
17.
Natriuretic peptide receptor 3 (NPR3) is regulated by microRNA-100.
J Mol Cell Cardiol
; 82: 13-21, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25736855
18.
Hypoxia-induced stabilization of HIF2A promotes cardiomyocyte proliferation by attenuating DNA damage.
J Cardiovasc Aging
; 4(1)2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38455514
19.
Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells.
Elife
; 132024 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38164941
20.
Foregut bypass vs. restrictive bariatric procedures for nonalcoholic fatty liver disease: a meta-analysis of 3,355 individuals.
Hepatobiliary Surg Nutr
; 12(5): 658-670, 2023 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37886204